Results 101 to 110 of about 3,451,157 (398)
Human Cytomegalovirus Congenital (cCMV) Infection Following Primary and Nonprimary Maternal Infection: Perspectives of Prevention through Vaccine Development [PDF]
, 2020 Giuseppe Gerna, Daniele Lilleri
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LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1
Advanced Science, EarlyView.LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li +12 more
wiley +1 more source
Prevalence of Human Cytomegalovirus Infection in Iranian Prostate Cancer Patients [PDF]
, 2023 Ehsan Alborzi +7 more
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Advanced Science, EarlyView.Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu +11 more
wiley +1 more source
Cytomegalovirus establishes a latent reservoir and triggers long-lasting inflammation in the eye.
PLoS Pathogens, 2018 Recent outbreaks of Ebola and Zika have highlighted the possibility that viruses may cause enduring infections in tissues like the eye, including the neural retina, which have been considered immune privileged.
Valentina Voigt +7 more
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Advanced Science, EarlyView.This study identifies a new viral mechanism by a viral protein σ3 that functions as a vTR to suppress NF‐κB gene expression via its direct interaction with the host helicase DHX9. Through their interaction, σ3 not only impairs the initial recruitment of Pol II but also affects Pol II pause‐release and ultimately suppresses NF‐κB gene expression ...
Xueyang Pang +12 more
wiley +1 more source
Ultrasound indications for maternal STORCH testing in pregnancy
Swiss Medical Weekly, 2017 AIMS OF THE STUDY Fetal abnormalities found on ultrasonography lead to a variety of diagnostic procedures, including a panel of serologies to detect possible maternal STORCH infections encompassing syphilis, Toxoplasma gondii, rubella ...
Cora Alexandra Voekt +4 more
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Early-life cytomegalovirus infection is associated with gut microbiota perturbations and increased risk of atopy [PDF]
, 2021 Hind Sbihi +10 more
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Advanced Science, EarlyView.Upregulated TRMT6 forms aberrant hypermethylation of a specific tRNA pool and serves as a predictor of poor prognosis in TNBC. This m1A modification in tRNAs enhances translation of FTH1 and FTL, reducing the pool of bioavailable Fe2⁺. Reduced Fe2+ availability impairs RSL3‐induced lipid peroxidation and tumor progression.
Yuqing Lei +12 more
wiley +1 more source
An Evidence Against the Effect of Chronic Cytomegalovirus Infection in Unstable Angina Pectoris [PDF]
Acta Medica Iranica, 2011 Recent reports have suggested that cytomegalovirus (CMV) infection may contribute to risk of cardiovascular disease. However, relationship between CMV infection and unstable angina (UA) is controversial and studies about this subject in Iran and even ...
Seyed Mohammad Alavi +2 more
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