Results 41 to 50 of about 15,699 (268)

Sustained gene expression in the retina by improved episomal vectors [PDF]

, 2014
Gene and cellular therapies are nowadays part of therapeutic strategies for the treatment of diverse pathologies. The drawbacks associated with gene therapy-low levels of transgene expression, vector loss during mitosis, and gene silencing-need to be ...
Ana V. Oliveira, Conley S.M., Davis A.A., Gabriela A. Silva, Reinisalo M., Rudolf Haase, Sofia M. Calado, Susana Machado   +7 more
core   +1 more source

CLINICAL MANIFESTATIONS AND CD4 COUNT CHARACTERISTICS OF PATIENTS WITH CYTOMEGALOVIRUS (CMV) RETINITIS

IJRETINA (International Journal of Retina), 2022
Introduction: To describe the clinical manifestations and CD4 count characteristics of patients with cytomegalovirus (CMV) retinitis. Methods: This is a retrospective study of patients diagnosed with CMV retinitis at the Ophthalmology Outpatient ...
Yunneke Renna Xaverina, Ovi Sofia
doaj   +1 more source

Acute Progressive Visual Loss in a Case of Acute Myeloid Leukemia: Challenges in the Utility of Molecular Tests in Early Diagnose of Cytomegalovirus Retinitis

Case Reports in Medicine, 2018
Cytomegalovirus (CMV) retinitis is one of the rare but debilitating presentations of the CMV infection in children with leukemia. Herein, we report a 12-year-old boy with acute myeloid leukemia complicated by rapid progressive visual loss during relapse ...
Ali Amanati, Nader Shakibazad, Bahman Pourabbas, Mohammad Hossein Nowroozzadeh, Soheila Zareifar, Omid Reza Zekavat   +5 more
doaj   +1 more source

AIDS-defining illnesses at initial diagnosis of HIV in a large Guatemalan cohort [PDF]

, 2017
BackgroundAnecdotal evidence suggests that a high proportion of patients diagnosed with HIV in Guatemala present with AIDS. There remain limited data on the epidemiology of AIDS-defining illnesses (ADIs) in Central America.MethodsWe conducted a ...
Cordon, Andrea Alonzo, Melendez, Johanna, Powderly, William G, Reinhardt, Samuel W, Ross, Ian, Spec, Andrej, Villatoro, Carlos Mejia   +6 more
core   +2 more sources

Long Term Therapy of Cytomegalovirus Retinitis with Ganciclovir in a Child with Acquired Immunodeficiency Syndrome

Canadian Journal of Infectious Diseases, 1993
Cytomegalovirus retinitis is the most severe ophthalmological complication of patients with acquired immune deficiency syndrome (aids). Ganciclovir must be given continuously to control progression of the disease or relapse typically occurs.
Scott A Halperin, G Robert La Roche
doaj   +1 more source

Bilateral extensive CMV retinitis in a sick child – Harbinger of severe combined immunodeficiency

Journal of Pediatric Critical Care, 2017
Cytomegalovirus (CMV) retinitis is a marker of severe cellular immunodeficiency. Severe combined immunodeficiency (SCID) must be considered in infants presenting with CMV retinitis in a non-HIV setting.
H S Vinayaka, Tummala Sujith Kumar, G V Basavaraj, Sagar Bhattad   +3 more
doaj   +1 more source

High ocular CMV copies and mismatched receipts may predict poor visual prognosis in CMV retinitis patients following allogeneic haematopoietic stem cell transplantation

BMC Ophthalmology, 2017
Background To summarize the clinical characteristics and potential factors affecting the visual outcomes in patients with cytomegalovirus retinitis following allogeneic haematopoietic stem cell transplantation (HSCT).
Yuehong Zhang, Xiangcai Ruan, Weizhong Yang, Ling Li, Zhuanhua Xian, Qiting Feng, Wenjian Mo   +6 more
doaj   +1 more source

Cytomegalovirus retinitis following dexamethasone intravitreal implant

American Journal of Ophthalmology Case Reports, 2021
Purpose: To describe a case of Cytomegalovirus (CMV) Retinitis in an immunocompetent patient following Dexamethasone Intravitreal Implant (DII). Observations: Retrospective chart review of a single patient.
Sarah G. Chaudhry, Adrian T. Fung
doaj   +1 more source

Posterior subhyaloid precipitates in cytomegalovirus retinitis [PDF]

, 2011
This study aims to report a novel finding of posterior subhyaloid precipitates (PSPs) in two patients with cytomegalovirus (CMV) retinitis. A small case series was conducted.
Raquel Goldhardt, Ninel Z. Gregori, Thomas Albini, Shalini Yalamanchi, Andres Emanuelli   +4 more
core   +1 more source

Bilateral acute necrotizing retinitis due to cytomegalovirus infection in an infant: Challenging case report

American Journal of Ophthalmology Case Reports, 2019
Purpose: To report a case of bilateral acute necrotising retinitis due to cytomegalovirus infection (CMV) in an Asian Indian infant. Observations: An Asian Indian infant born with a birth weight of 1000 g at 26 week of gestation acquired cytomegalovirus ...
Padmamalini Mahendradas, Shivani Sinha, Anand Vinekar, Maralusiddappa Pradeep, Bhujang K. Shetty   +4 more
doaj   +1 more source