Results 111 to 120 of about 1,309,246 (380)

Mad2, Bub3, and Mps1 regulate chromosome segregation and mitotic synchrony in Giardia intestinalis, a binucleate protist lacking an anaphase-promoting complex. [PDF]

, 2014
The binucleate pathogen Giardia intestinalis is a highly divergent eukaryote with a semiopen mitosis, lacking an anaphase-promoting complex/cyclosome (APC/C) and many of the mitotic checkpoint complex (MCC) proteins.
Cande, W Zacheus, Vicente, Juan-Jesus
core   +2 more sources

Influenza A Virus Assembly Intermediates Fuse in the Cytoplasm

PLoS Pathogens, 2014
Reassortment of influenza viral RNA (vRNA) segments in co-infected cells can lead to the emergence of viruses with pandemic potential. Replication of influenza vRNA occurs in the nucleus of infected cells, while progeny virions bud from the plasma ...
S. Lakdawala, Yicong Wu, Peter J Wawrzusin, J. Kabat, A. Broadbent, E. Lamirande, E. Fodor, N. Altan-Bonnet, H. Shroff, K. Subbarao   +9 more
semanticscholar   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Androgen receptor phosphorylation at serine 515 by Cdk1 predicts biochemical relapse in prostate cancer patients [PDF]

, 2013
<br>Background:Prostate cancer cell growth is dependent upon androgen receptor (AR) activation, which is regulated by specific kinases. The aim of the current study is to establish if AR phosphorylation by Cdk1 or ERK1/2 is of prognostic ...
BV Kallakury, C E Adams, C Tannahill, D Gioeli, D Gioeli, G Fyffe, GG Kuiper, H Y Leung, H Zong, HY Wong, J Edwards, J Ferlay, J M Willder, JC Obenauer, JS Diallo, K Shigemura, KS McCarty, LA Ponguta, LJ Blok, M A Underwood, M Mistry, M Roach, M Seywright, MS Cookson, NG Anderson, P Chymkowitch, P G Horgan, P McCall, R Mukherjee, RE Bakin, RK Tyagi, S Chen, S Chen, S J Heng, SM Powell, T Kirkegaard, T Ohta, WC Bell, Y Wen, Z Fu, ZX Zhou   +40 more
core   +1 more source

Differential and interactive effects of cytoplasmic substitution and seed ageing on submergence stress response in wheat (Triticum aestivum L.)

Biotechnology & Biotechnological Equipment, 2019
Cytoplasmic genomes affect various phenotypes, including abiotic stress responses, through interaction with nuclear genomes in plants. We focused on the effects of cytoplasmic substitution on germination and seedling growth in combinations with ...
Shotaro Takenaka, Ryohei Yamamoto, Chiharu Nakamura   +2 more
doaj   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source

Active colloidal particles in emulsion droplets: A model system for the cytoplasm

, 2018
In living cells, molecular motors create activity that enhances the diffusion of particles throughout the cytoplasm, and not just ones attached to the motors. We demonstrate initial steps toward creating artificial cells that mimic this phenomenon.
Chambers, Zachary C., Dimiduk, Thomas G., Gözen, İrep, Horowitz, Viva R., Manoharan, Vinothan N.   +4 more
core   +1 more source

Modelling the Establishment of PAR Protein Polarity in the One-Cell C. elegans Embryo [PDF]

, 2008
At the one-cell stage, the C. elegans embryo becomes polarized along the anterior-posterior axis. The PAR proteins form complementary anterior and posterior domains in a dynamic process driven by cytoskeletal rearrangement.
Aceto, Benton, Boyd, Cheeks, Cuenca, DeRenzo, Duncan, D’Agostino, Filipe Tostevin, Goldstein, Goldstein, Guo, Hao, Hird, Houchmandzadeh, Hung, Jenkins, Kemphues, Kemphues, Lipkow, Macara, Martin Howard, Morton, Munro, Nishimura, Ogura, Pagano, Rappleye, Schonegg, Schubert, Seydoux, Strome, Strome, Sulston, Suzuki, Tabuse, Watts   +36 more
core   +3 more sources

The Ether-soluble Substances of Cabbage Leaf Cytoplasm [PDF]

, 1927
Albert Charles Chibnall, Harold John Channon   +1 more
openalex   +3 more sources

Etymologia: Histoplasma capsulatum

Emerging Infectious Diseases, 2021
Monika Mahajan
doaj   +1 more source