Results 111 to 120 of about 1,653,701 (332)

Protein diffusion in mammalian cell cytoplasm.

open access: yesPLoS ONE, 2011
We introduce a new method for mesoscopic modeling of protein diffusion in an entire cell. This method is based on the construction of a three-dimensional digital model cell from confocal microscopy data.
Thomas Kühn   +7 more
doaj   +1 more source

A5 cytoplasm: way to three way forage pearl millet hybrids

open access: yesElectronic Journal of Plant Breeding, 2021
In the present study, two CMS lines viz., ICMA 03333 and ICMA 01777 based on A5 cytoplasm were used. These A5 lines were crossed with maintainers of different cytoplasmic sources during kharif 2016.
Sarabjeet Singh, R. Bhardwaj* and R. S. Sohu
doaj   +1 more source

Modeling reaction-diffusion of molecules on surface and in volume spaces with the E-Cell System [PDF]

open access: yes, 2009
The-Cell System is an advanced open-source simulation platform to model and analyze biochemical reaction networks. The present algorithm modules of the system assume that the reacting molecules are all homogeneously distributed in the reaction ...
Masaru Tomita, Satya N. V. Arjunan
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Differential and interactive effects of cytoplasmic substitution and seed ageing on submergence stress response in wheat (Triticum aestivum L.)

open access: yesBiotechnology & Biotechnological Equipment, 2019
Cytoplasmic genomes affect various phenotypes, including abiotic stress responses, through interaction with nuclear genomes in plants. We focused on the effects of cytoplasmic substitution on germination and seedling growth in combinations with ...
Shotaro Takenaka   +2 more
doaj   +1 more source

Dynamics of Bacteriophage Genome Ejection In Vitro and In Vivo

open access: yes, 2010
Bacteriophages, phages for short, are viruses of bacteria. The majority of phages contain a double-stranded DNA genome packaged in a capsid at a density of ~500 mg/ml. This high density requires substantial compression of the normal B form helix, leading
Molineux, Ian J., Panja, Debabrata
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

PCR identification of Petunia male sterile cytoplasm

open access: yesOrnamental Horticulture, 2019
Petunia is a very important ornamental plant with a broad range of flower colour and size, and most of the cultivars grown are propagated through seeds.
Noemí Colombo, Juan Carlos Hagiwara
doaj   +1 more source

The site of ribonucleic acid synthesis in the isolated nucleus [PDF]

open access: yes, 1961
There is still controversy concerning the primary site of RNA synthesis in the cell.(1) When tissues are radioautographed after administration of radioactive inorganic phosphorus or radioactive RNA(2) precursors such as tritiated uridine or cytidine, it ...
Bonner, James, Rho, Joon H.
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy