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Cytoplasmic dynein: advances in microtubule-based motility
Trends in Cell Biology, 1991It is four years since the discovery that a cytoplasmic form of dynein was able to produce force along microtubules in the opposite direction to kinesin. Recent evidence has supported a role for this cytoplasmic dynein in retrograde organelle transport, as well as other forms of intracellular motility.
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Single-molecule imaging of cytoplasmic dynein in vivo
2015While early fluorescence microscopy experiments employing fluorescent probes afforded snapshots of the cell, the power of live-cell microscopy is required to understand complex dynamics in biological processes. The first successful cloning of green fluorescent protein in the 1990s paved the way for development of approaches that we now utilize for ...
Ananthanarayanan, Vaishnavi +1 more
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Structure, function and regulation of cytoplasmic dynein
Current Opinion in Cell Biology, 1994Molecular cloning studies have provided valuable structural information about the different subunits of cytoplasmic dynein and their relationships to their axonemal dynein counterparts. Recent unexpected findings regarding the role of this enzyme in mitosis have emerged from mutational analyses and microinjection experiments, while studies of organelle
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Cytoplasmic dynein during mitosis
2018Edward H. Hinchcliffe, Kevin T. Vaughan
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Cytoplasmic dynein dysfunction and neurodegenerative disease
2012Armen J. Moughamian, Erika L.F. Holzbaur
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