Results 131 to 140 of about 60,691 (243)

LRRK2 as a Potential Disease‐Modifying Target in Sporadic Parkinson's Disease

Movement Disorders, EarlyView.
Abstract A growing understanding of the role that leucine‐rich repeat kinase 2 (LRRK2) plays in Parkinson's disease (PD) supports continued focus on this enzyme as a therapeutic target for PD. Accumulating evidence suggests that there are phenotypic, neuropathologic, and biological similarities between sporadic PD (sPD) and familial forms in which ...
Anthony E. Lang, Robert A. Hauser, Lorraine V. Kalia, Bonnie Hersh, Zdenek Berger, Roy Llorens Arenas, Coro Paisan‐Ruiz, Kyle Fraser, Danna Jennings, Jillian H. Kluss, Sarah Huntwork‐Rodriguez, Anastasia G. Henry, J. Timothy Greenamyre   +12 more
wiley   +1 more source

Respiratory Syncytial Virus (RSV): A Comprehensive Overview From Basic Biology to Clinical Prevention and Control

Medicinal Research Reviews, EarlyView.
ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi, Xiya Huang, Chunjun Ye, Yishan Lu, Yanyan Liu, Yuquan Wei, Xiawei Wei   +6 more
wiley   +1 more source

Recent Progress in Treating Airway Mucus Hypersecretion by Targeting the Epidermal Growth Factor Receptor Signaling Pathway

Pediatric Discovery, EarlyView.
ABSTRACT Asthma, chronic pulmonary obstructive disease (COPD), cystic fibrosis, and acute respiratory infections are severe respiratory conditions that significantly contribute to global morbidity and mortality. Airway mucus hypersecretion is an important common pathophysiological and clinical manifestation of these diseases and is closely associated ...
Yuanyuan Zhang, Fuping Yang, Chunyu Yan, Yu Deng, Enmei Liu   +4 more
wiley   +1 more source

GAG Protein of <i>Arabidopsis thaliana</i> LTR Retrotransposon Forms Retrosome-like Cytoplasmic Granules and Activates Stress Response Genes. [PDF]

Plants (Basel)
Polkhovskiy A, Komakhin R, Kirov I.
europepmc   +1 more source

Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity

, 2016
J. Gavin Daigle, Karthik Krishnamurthy, Nandini Ramesh, Ian Casci, John Monaghan, Kevin McAvoy, Earl W. Godfrey, Dianne C. Daniel, Edward M. Johnson, Zachary Monahan, Frank Shewmaker, Piera Pasinelli, Udai Bhan Pandey   +12 more
openalex   +1 more source

From flower buds to bolls: how cotton reproductive structures shape boll weevil development, reproduction and survival

Pest Management Science, EarlyView.
Female boll weevils feeding on flower buds promote reproduction regardless of their immature diet, whereas boll feeding increases lipid reserves and lifespan, revealing a nutrition‐driven trade‐off that sustains survival and reproduction in tropical boll weevil populations.
Roberta Ramos Coelho, Guilherme Gomes Rolim, Franklin Magliano da Cunha, Valéria Wanderley‐Teixeira, José Dijair Antonino, Jorge Braz Torres   +5 more
wiley   +1 more source

Interactions of cytoplasmic granules with microtubules in human neutrophils. [PDF]

, 1989
Stephen W. Rothwell, J Nath, Daniel G. Wright   +2 more
openalex   +1 more source

Plate tectonics in the microscopy realm: Molecular insights into morphological variability of Peridinium willei (Peridiniales, Dinophyceae)

TAXON, EarlyView.
Abstract Freshwater Peridinium willei (Peridiniaceae) is globally distributed, but reports linking its morphologies with DNA sequence data remain scarce. The taxonomy of the species, and its infraspecific taxa, remain ambiguous due to the lack of DNA sequence data for the original and type material.
Arwin Ahmadpur, Dana C. Eisenhöld, Eva Facher, Marc Gottschling, Selin Gürkan, Borislava P. Hristova, Johanna Knechtel, Paula M.E. Lehner, Hemingway Nyoka, Paweł M. Owsianny, Chiara Peters, Hélène Reich, Eva Reicheneder, Alexander Rockinger, Cecilia Teodora Satta, Marina Stark, F. Sara Uslu, Anže Žerdoner Čalasan   +17 more
wiley   +1 more source

Genetic Pigmentary Disorders: From Molecular Mechanisms to Clinical Manifestations

The Journal of Dermatology, EarlyView.
ABSTRACT Genetic pigmentary disorders represent a diverse group of genetic conditions characterized by alterations in melanin production and transport and melanocyte development, resulting from single‐gene pathological variants. These disorders encompass both hypopigmentary and hyperpigmentary phenotypes, affecting not only skin pigmentation but also ...
Ken Okamura, Tamio Suzuki
wiley   +1 more source

GROWTH AND DIFFERENTIATION OF CYTOPLASMIC MEMBRANES IN THE COURSE OF LIPOPROTEIN GRANULE SYNTHESIS IN THE HEPATIC CELL [PDF]

, 1970
Albert Claude
openalex   +1 more source