Results 151 to 160 of about 272,495 (294)
Developmental Dynamics, EarlyView.Abstract Background Fibrillins provide a scaffold for elastic fiber formation, which enables lung recoil and aortic compliance. Abnormal fibrillin microfibrils, as in Marfan syndrome, lead to enlarged alveoli, vascular stiffening, and aneurysms. Our earlier studies suggested that fibrillin function depends on O‐glucosylation of its epidermal growth ...
Sanjiv Neupane +4 more
wiley +1 more source
Hypergranular precursor B-cell acute lymphoblastic leukemia in a 16-year-old boy
Indian Journal of Pathology and Microbiology, 2009 Presence of cytoplasmic granules in the blasts is a well known feature of myeloid leukemia. ALL presenting with the numerous cytoplasmic granules in blasts is a rarity and may be misdiagnosed as acute myeloid leukemia.
Tembhare Prashant +5 more
doaj
FMRP Associates with Cytoplasmic Granules at the Onset of Meiosis in the Human Oocyte. [PDF]
PLoS One, 2016 Rosario R +6 more
europepmc +1 more source
β‐Hydroxybutyrate reduces neuronal excitability via GIRK channels
Epilepsia, EarlyView.β‐Hydroxybutyrate decreases neuronal excitability by activating GIRK channels through HCAR2 signaling, providing a cellular mechanism that may contribute to the antiseizure effects of the ketogenic diet. Abstract Objective The ketogenic diet is used to treat drug‐resistant epilepsy, yet the molecular mechanisms coupling metabolic state to seizure ...
Soudabeh Naderi +8 more
wiley +1 more source
Epilepsia Open, EarlyView.Abstract Objective Epilepsy affects approximately 50 million people worldwide and, although primarily attributed to neuronal dysfunction, increasing evidence highlights a critical role of glial cells, particularly astrocytes, in the pathophysiological mechanisms.
Chiara Lötzsch +5 more
wiley +1 more source
Grassland Research, EarlyView.Abstract Background Seed shattering limits the production of Elymus sibiricus L., and application of exogenous brassinosteroid significantly alleviates plant organ abscission. Methods To explore the potential regulatory network of brassinosteroid on seed shattering, the abscission zone of E. sibiricus cv. Lanyu No.
Huanhuan Lu +6 more
wiley +1 more source
International Journal of Aquatic Biology, 2016 The histological status of adrenocortical tissues and the correlated seasonal changes in ovarian activities in Mystus vittatus was performed. The tubules and nests of interrenal and chromaffin cells were located in cephalic kidney around the main ...
Padmanabha Chakrabarti, Mainak Banerjee
doaj
Epirubicin Alters Pancreatic Autophagy and Insulin Synthesis Through a Zinc‐Dependent Mechanism
Journal of Applied Toxicology, EarlyView.ABSTRACT Epirubicin (EPI) can cause metabolic side effects, including chemotherapy‐related diabetes, partly through oxidative stress that disrupts zinc (Zn) homeostasis and impairs autophagy. This study investigated the effects of EPI on Zn regulation and autophagy in the pancreas, as well as the modulatory role of N‐acetylcysteine (NAC). Rats received
Ebru Afşar, Işıl Eranıl
wiley +1 more source
, 1997 Transforming growth factor-alpha (TGF-alpha) exerts several effects on target cells, such as neovascularization promotion and mitogenic signalling. Using immunoelectron microscopy, we show that monocytes and neutrophils, store TGF-alpha in cytoplasmic ...
Knol, EF +5 more
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