Human FUS is toxic via association with RNA polymerase II in Drosophila. [PDF]
Moens TG +7 more
europepmc +1 more source
World Health Organization classification of tumours of the breast 6th edition 2026
The 6th edition of the World Health Organization Classification of Breast Tumours introduces changes based on recent advances in our understanding of breast biology, developments in diagnostic modalities, identification of specific molecular targets and new treatment regimes.
Cecily Quinn +47 more
wiley +1 more source
ABSTRACT Introduction Neutrophil‐extracellular traps are net‐like material released by triggered neutrophils and composed of decondensed chromatin linked to nuclear proteins. Elastase, one of the fourth most represented neutrophil‐specific serine proteases stored in azurophil granules of naïve neutrophils, exerts various actions, including degradation ...
Pasqualina Scala +14 more
wiley +1 more source
Cytochemical Characterization for Macrophages Engulf Cholesterol Crystals and Myeloperoxidase in Neutrophil Extracellular Traps (NETs) Sampled From Disrupted Aortic Plaques. [PDF]
Iwa N +7 more
europepmc +1 more source
RNA-protein complexes as key regulators of plant secondary metabolism: Biophysical interactions and functional significance. [PDF]
Ugwu OP +4 more
europepmc +1 more source
ABSTRACT Objectives Digital morphology (DM) systems assisted by artificial intelligence are increasingly being introduced into hematology laboratories; however, data on their performance in routine clinical practice for bone marrow aspirates (BMA) remain limited.
Gina Zini +6 more
wiley +1 more source
Phagocytic Mesothelial Cells in Pericardial Effusion Following Allogeneic Peripheral Blood Stem Cell Transplantation for Chronic Active Epstein-Barr Virus Infection: A Distinctive Cytomorphological and Immunocytochemical Case Study. [PDF]
Satomi H +5 more
europepmc +1 more source
Calcium oxalate monohydrate (COM) crystals cause changes in the secretion of 29 proteins from neutrophil‐like cells, including those involved in neutrophil immune activation and intracellular metabolic adaptation. The neutrophil secreted proteins (secretome) also inhibit calcium oxalate crystallisation and crystal growth, but promote crystal ...
Chanettee Lertprapai +2 more
wiley +1 more source
Understanding liquid-liquid phase separation through TDP-43: fundamental principles, subcellular compartmentalisation, and role of solid inclusion formation. [PDF]
Bigi A, Chiti F.
europepmc +1 more source
NAA10 and BTRC drive CREBRF degradation in endoplasmic reticulum stress and renal tubular injury
In diabetic kidney disease (DKD), the acetyltransferase NAA10 mediates the acetylation of CREBRF, promoting its recognition and binding by the E3 ubiquitin ligase BTRC, thereby enhancing the ubiquitination level of CREBRF and accelerating its degradation.
Sitian Fang +3 more
wiley +1 more source

