RNA Granules: A View from the RNA Perspective [PDF]
Molecules, 2020 RNA granules are ubiquitous. Composed of RNA-binding proteins and RNAs, they provide functional compartmentalization within cells. They are inextricably linked with RNA biology and as such are often referred to as the hubs for post-transcriptional ...
Siran Tian +2 more
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Plant RNA Regulatory Network and RNA Granules in Virus Infection [PDF]
Frontiers in Plant Science, 2017 Regulation of post-transcriptional gene expression on mRNA level in eukaryotic cells includes translocation, translation, translational repression, storage, mRNA decay, RNA silencing, and nonsense-mediated decay.
Kristiina Mäkinen +2 more
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Regulation of RNG105/caprin1 dynamics by pathogenic cytoplasmic FUS and TDP-43 in neuronal RNA granules modulates synaptic loss [PDF]
Heliyon, 2023 In neurodegenerative diseases, the condensation of FUS and TDP-43 with RNA granules in neurons is linked to pathology, including synaptic disorders. However, the effects of FUS and TDP-43 on RNA granule factors remain unclear.
Tomoyo Horio +3 more
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RNA Granules in Antiviral Innate Immunity: A Kaposi’s Sarcoma-Associated Herpesvirus Journey [PDF]
Frontiers in Microbiology, 2022 RNA granules are cytoplasmic, non-membranous ribonucleoprotein compartments that form ubiquitously and are often referred to as foci for post-transcriptional gene regulation.
Nishi R. Sharma, Zhi-Ming Zheng
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Cataloguing and Selection of mRNAs Localized to Dendrites in Neurons and Regulated by RNA-Binding Proteins in RNA Granules [PDF]
Biomolecules, 2020 Spatiotemporal translational regulation plays a key role in determining cell fate and function. Specifically, in neurons, local translation in dendrites is essential for synaptic plasticity and long-term memory formation.
Rie Ohashi, Nobuyuki Shiina
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Transcription arrest induces formation of RNA granules in mitochondria [PDF]
Life Science AllianceIn this study, the spatial distribution of mitochondrial-encoded RNAs is investigated and shows that upon transcription arrest, RNAs form granules that show protectivity for transcripts.
Katja G Hansen +4 more
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Who Regulates Whom? An Overview of RNA Granules and Viral Infections [PDF]
Viruses, 2016 After viral infection, host cells respond by mounting an anti-viral stress response in order to create a hostile atmosphere for viral replication, leading to the shut-off of mRNA translation (protein synthesis) and the assembly of RNA granules.
Natalia Poblete-Durán +4 more
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Silencing and translation in RNA granules: a tale of sand grains [PDF]
Frontiers in Molecular Neuroscience, 2014 The transcriptome at the synapse consists of thousands of messengers encoding a plethora of cellular functions, including an important number of receptors and ion channels and associated proteins.
Jerónimo ePimentel +3 more
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CGG Repeats in the 5'UTR of FMR1 RNA Regulate Translation of Other RNAs Localized in the Same RNA Granules. [PDF]
PLoS ONE, 2016 CGG repeats in the 5'UTR of Fragile X Mental Retardation 1 (FMR1) RNA mediate RNA localization and translation in granules. Large expansions of CGG repeats (> 200 repeats) in FMR1, referred to as full mutations, are associated with fragile X syndrome ...
René Rovozzo +6 more
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Localisation of RNAs into the germ plasm of vitellogenic xenopus oocytes [PDF]
, 2013 We have studied the localisation of mRNAs in full-grown Xenopus laevis oocytes by injecting fluorescent RNAs, followed by confocal microscopy of the oocyte cortex.
B Heinrich +66 more
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