Results 21 to 30 of about 874,898 (240)

EGFP-FMRP Granules Are Proto-Granules That Can Be Shunted to Stress Granules During a Stress Response [PDF]

open access: yes, 2010
Overexpressed EGFP-FMRP has been used as a substitute for endogenous fragile X mental retardation protein (FMRP) in protein-protein interaction studies, and in studies concerning the composition, the formation and the localization of neuronal granules ...
Robert Denman
core   +1 more source

Characterization of Fragile X Mental Retardation Protein granules formation and dynamics in Drosophila

open access: yesBiology Open, 2012
Summary FMRP is an evolutionarily conserved protein that is highly expressed in neurons and its deficiency causes fragile X mental retardation syndrome.
Cristina Gareau   +4 more
doaj   +1 more source

Intracellular and intercellular transport of RNA organelles in CXG repeat disorders: The strength of weak ties

open access: yesFrontiers in Molecular Biosciences, 2022
RNA is a vital biomolecule, the function of which is tightly spatiotemporally regulated. RNA organelles are biological structures that either membrane-less or surrounded by membrane.
Deepti Kailash Nabariya   +3 more
doaj   +1 more source

Germ Granules Allow Transmission of Small RNA-Based Parental Responses in the “Germ Plasm”

open access: yesiScience, 2020
Summary: In the recent decade small RNA-based inheritance has been implicated in a variety of transmitted physiological responses to the environment. In Caenorhabditis elegans, heritable small RNAs rely on RNA-dependent RNA polymerases, RNA-processing ...
Itamar Lev, Oded Rechavi
doaj   +1 more source

Mitochondrial RNA granules: Compartmentalizing mitochondrial gene expression [PDF]

open access: yesJournal of Cell Biology, 2016
Alexis A. Jourdain, Jean-Claude Martinou
exaly   +2 more sources

The influence of viral RNA secondary structure on interactions with innate host cell defences [PDF]

open access: yes, 2013
RNA viruses infecting vertebrates differ fundamentally in their ability to establish persistent infections with markedly different patterns of transmission, disease mechanisms and evolutionary relationships with their hosts.
Blundell, Richard   +13 more
core   +1 more source

RNA granules in neuronal plasticity and disease

open access: yes, 2023
International audienceRNA granules are dynamic entities controlling the spatiotemporal distribution and translation of RNA molecules. In neurons, a variety of RNA granules exist both in the soma and in cellular processes.
Karl E. Bauer   +7 more
core   +1 more source

Dynamics and Functions of Stress Granules and Processing Bodies in Plants

open access: yesPlants, 2020
RNA granules, such as stress granules and processing bodies, can balance the storage, degradation, and translation of mRNAs in diverse eukaryotic organisms.
Geng-Jen Jang   +2 more
doaj   +1 more source

Assay to Study the Phase-transition Behavior of Edc3, a Conserved Processing Body (P-body) Marker Protein

open access: yesBio-Protocol, 2022
RNA granules are conserved, non-membranous, biphasic structures predominantly composed of RNA and RNA-binding proteins. RNA granules often assemble as a result of cellular responses to a variety of stresses, including infection. Two types of RNA granules
Raju Roy, Purusharth Rajyaguru
doaj   +1 more source

Maf1-mediated repression of RNA polymerase III transcription inhibits tRNA degradation via RTD pathway [PDF]

open access: yes, 2012
tRNA precursors, which are transcribed by RNA polymerase III, undergo end-maturation, splicing and base modifications. Hypomodified tRNAs, such as tRNAVal(AAC), lacking 7-methylguanosine and 5-methylcytidine modifications, are subject to degradation by a
Boguta, Magdalena   +3 more
core   +1 more source

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