Results 31 to 40 of about 874,898 (240)

Interactome of Two Diverse RNA Granules Links mRNA Localization to Translational Repression in Neurons

open access: yesCell Reports, 2013
Transport of RNAs to dendrites occurs in neuronal RNA granules, which allows local synthesis of specific proteins at active synapses on demand, thereby contributing to learning and memory.
Renate Fritzsche   +20 more
doaj   +1 more source

Localisation of RNAs into the germ plasm of vitellogenic xenopus oocytes [PDF]

open access: yes, 2013
We have studied the localisation of mRNAs in full-grown Xenopus laevis oocytes by injecting fluorescent RNAs, followed by confocal microscopy of the oocyte cortex.
Nijjar, Sarbjit   +5 more
core   +2 more sources

Xp54 and related (DDX6-like) RNA helicases : roles in messenger RNP assembly, translation regulation and RNA degradation [PDF]

open access: yes, 2006
The DEAD-box RNA helicase Xp54 is an integral component of the messenger ribonucleoprotein (mRNP) particles of Xenopus oocytes. In oocytes, several abundant proteins bind pre-mRNA transcripts to modulate nuclear export, RNA stability and translational ...
Weston, A, Sommerville, John
core   +1 more source

Role of the RNA-binding protein Nrd1 in stress granule formation and its implication in the stress response in fission yeast. [PDF]

open access: yesPLoS ONE, 2012
We have previously identified the RNA recognition motif (RRM)-type RNA-binding protein Nrd1 as an important regulator of the posttranscriptional expression of myosin in fission yeast.
Ryosuke Satoh   +10 more
doaj   +1 more source

Stress granules in the spinal muscular atrophy and amyotrophic lateral sclerosis: The correlation and promising therapy

open access: yesNeurobiology of Disease, 2022
Increasing genetic and biochemical evidence has broadened our view of the pathomechanisms that lead to Spinal muscular atrophy (SMA) and Amyotrophic lateral sclerosis (ALS), two fatal neurodegenerative diseases with similar symptoms and causes.
LiDan Hu   +5 more
doaj   +1 more source

Spatial patterning of P granules by RNA-induced phase separation of the intrinsically-disordered protein MEG-3

open access: yeseLife, 2016
RNA granules are non-membrane bound cellular compartments that contain RNA and RNA binding proteins. The molecular mechanisms that regulate the spatial distribution of RNA granules in cells are poorly understood. During polarization of the C.
Jarrett Smith   +5 more
doaj   +1 more source

RNA-specific ribonucleotidyl transferases [PDF]

open access: yes, 2007
RNA-specific nucleotidyl transferases (rNTrs) are a diverse family of template-independent polymerases that add ribonucleotides to the 3'-ends of RNA molecules.
Keller, W.   +3 more
core   +1 more source

The deacetylase HDAC6 is an essential component of stress granules and plays a critical role in the cellular response to stress [PDF]

open access: yes, 2007
The reversible acetylation of histones has a critical role in transcriptional regulation. Likewise reversible acetylation of non-histones proteins is also important for other cellular processes.
Kwon, So Hee
core   +1 more source

Cytoplasmic RNA Granules and Viral Infection [PDF]

open access: yesAnnual Review of Virology, 2014
Richard E Lloyd
exaly   +2 more sources

An essential role of KREPB4 in RNA editing and structural integrity of the editosome in Trypanosoma brucei [PDF]

open access: yes, 2007
RNA editing in the sleeping sickness parasite Trypanosoma brucei remodels mitochondrial transcripts by the addition and deletion of uridylates as specified by guide RNAs.
Schnaufer, Achim; id_orcid   +4 more
core   +1 more source

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