Results 191 to 200 of about 62,398 (262)

From development to disease: the neuronal role of hnRNPs through the lens of <i>Drosophila</i>. [PDF]

open access: yesFront Cell Dev Biol
Stefanelli C   +3 more
europepmc   +1 more source

Assessment of the Performance of Siemens Scopio Digital Morphology on Bone Marrow Aspirates in Onco‐Hematology

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Objectives Digital morphology (DM) systems assisted by artificial intelligence are increasingly being introduced into hematology laboratories; however, data on their performance in routine clinical practice for bone marrow aspirates (BMA) remain limited.
Gina Zini   +6 more
wiley   +1 more source

Mast Cells Are a Reservoir of NLRP1 in Human Skin. [PDF]

open access: yesInt J Mol Sci
Dobre A   +14 more
europepmc   +1 more source

Mast Cells Selectively Deliver Extracellular Vesicle‐Encapsulated mRNA to Colorectal Cancer Cells

open access: yesImmunology &Cell Biology, EarlyView.
Schematic overview of mast cell‐colorectal cancer cell interactions. Mast cells bind to colorectal cancer cells through integrin‐mediated adhesion (1). Calcium influx arises in mast cells (2). Calcium signaling is required for the release of mRNA‐ and protein‐containing vesicles (3), resulting in the transfer of mast cell‐derived mRNA and proteins to ...
Rosie Lanzloth   +4 more
wiley   +1 more source

Myo1g Mediates NKR‐P1C Expression in Primary Mouse NK Cells and Participates in Cytotoxicity

open access: yesImmunology, EarlyView.
In this study we analysed the participation of Myosin 1g in the development and functions of murine natural killer (NK) cells; we found that Myosin 1g is expressed in murine‐activated primary NK cells from the spleen. Additionally, in the absence of Myosin 1g, correlates with a reduced expression of NKR‐P1C but not of CD49b or NKp46.
Héctor Romero‐Ramírez   +3 more
wiley   +1 more source

Targeting the miR‐224‐5p/PTEN pathway: A previously under‐characterized strategy to attenuate mesangial cell injury and predict prognosis in diabetic nephropathy

open access: yesJournal of Diabetes Investigation, EarlyView.
Serum miR‐224‐5p levels are progressively elevated in diabetic nephropathy (DN) and serve as an independent predictor of a decline in eGFR of ≥30% over 2 years. Mechanistically, miR‐224‐5p directly targets PTEN 3’‐UTR, suppressing PTEN and the activation of the AKT pathway in high‐glucose‐stimulated mesangial cells.
Yanxia Gao   +3 more
wiley   +1 more source

Melanoma and Other Melanistic Lesions in Brown Bullhead Ameiurus nebulosus From Waterbodies in the Northeastern United States and Canada: Identification of Risk Factors

open access: yesJournal of Fish Diseases, EarlyView.
ABSTRACT Melanistic lesions, including non‐raised black areas due to proliferations of melanocytes and melanomacrophages in the dermis and epidermis, as well as raised black areas consistent with melanoma, are described in brown bullhead (BBH) Ameiurus nebulosus from three water bodies in the northeastern United States and Quebec, Canada.
Vicki S. Blazer   +9 more
wiley   +1 more source

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