Results 81 to 90 of about 469,945 (221)

The effect of PRMT1-mediated arginine methylation on the subcellular localization, stress granules, and detergent-insoluble aggregates of FUS/TLS. [PDF]

open access: yesPLoS ONE, 2012
Fused in sarcoma/translocated in liposarcoma (FUS/TLS) is one of causative genes for familial amyotrophic lateral sclerosis (ALS). In order to identify binding partners for FUS/TLS, we performed a yeast two-hybrid screening and found that protein ...
Atsushi Yamaguchi, Keiko Kitajo
doaj   +1 more source

Immunofluorescence visualization of germ-line-specific cytoplasmic granules in embryos, larvae, and adults of Caenorhabditis elegans.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1982
By using fluorescent antibody staining, we have followed cytoplasmic granules unique to germ-line cells throughout the life cycle of Caenorhabditis elegans.
S. Strome, W. Wood
semanticscholar   +1 more source

Mislocalization of pathogenic RBM20 variants in dilated cardiomyopathy is caused by loss-of-interaction with Transportin-3

open access: yesNature Communications, 2023
Severe forms of dilated cardiomyopathy (DCM) are associated with point mutations in the alternative splicing regulator RBM20 that are frequently located in the arginine/serine-rich domain (RS-domain).
Julia Kornienko   +18 more
doaj   +1 more source

Superdiffusion dominates intracellular particle motion in the supercrowded space of pathogenic Acanthamoeba castellanii [PDF]

open access: yesScientific Reports 5, 11690 (2015), 2015
Acanthamoebae are free-living protists and human pathogens, whose cellular functions and pathogenicity strongly depend on the transport of intracellular vesicles and granules through the cytosol. Using high-speed live cell imaging in combination with single-particle tracking analysis, we show here that the motion of endogenous intracellular particles ...
arxiv  

Rock mechanics modeling based on soft granulation theory [PDF]

open access: yes, 2008
This paper describes application of information granulation theory, on the design of rock engineering flowcharts. Firstly, an overall flowchart, based on information granulation theory has been highlighted. Information granulation theory, in crisp (non-fuzzy) or fuzzy format, can take into account engineering experiences (especially in fuzzy shape ...
arxiv   +1 more source

Purification and properties of cytoplasmic granules from cytotoxic rat LGL tumors.

open access: yesJournal of Immunology, 1984
To evaluate the role of NK cell granules in the lytic activity of NK cells, cytoplasmic granules of rat NK tumors were purified by centrifugation of the cell homogenates in a Percoll gradient.
P. Millard   +3 more
semanticscholar   +1 more source

Nab3's localization to a nuclear granule in response to nutrient deprivation is determined by its essential prion-like domain.

open access: yesPLoS ONE, 2018
Ribonucleoprotein (RNP) granules are higher order assemblies of RNA, RNA-binding proteins, and other proteins, that regulate the transcriptome and protect RNAs from environmental challenge.
Travis J Loya   +4 more
doaj   +1 more source

Constrained Multi-shape Evolution for Overlapping Cytoplasm Segmentation [PDF]

open access: yesarXiv, 2020
Segmenting overlapping cytoplasm of cells in cervical smear images is a clinically essential task, for quantitatively measuring cell-level features in order to diagnose cervical cancer. This task, however, remains rather challenging, mainly due to the deficiency of intensity (or color) information in the overlapping region.
arxiv  

Differences in the behavior of cytoplasmic granules and lipid bodies during human lung mast cell degranulation

open access: yesJournal of Cell Biology, 1984
We used a morphometric and autoradiographic approach to analyze changes in specific cytoplasmic granules and cytoplasmic lipid bodies associated with human lung mast cell degranulation.
Ilan Hammel   +9 more
semanticscholar   +1 more source

Kinetics of fusion of the cytoplasmic granules with phagocytic vacuoles in human polymorphonuclear leukocytes. Biochemical and morphological studies

open access: yesJournal of Cell Biology, 1980
This study on human neutrophils was conducted to measure the kinetics of degranulation of the different cytoplasmic granules into phagocytic vacuoles, and to relate the timing of these events to the burst of respiration that accompanies phagocytosis by ...
A. Segal, J. Dorling, S. Coade
semanticscholar   +1 more source

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