Results 191 to 200 of about 136,619 (315)

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto, Samaneh Ghadami, Kristen Dellinger   +2 more
wiley   +1 more source

Methyliertes Cytosin [PDF]

, 2019
openaire   +1 more source

RNA degradomics and proteomics reveal the mechanism of dsProsβ1‐mediated proteasome targeting in Psylliodes chrysocephala

Pest Management Science, EarlyView.
RNA degradomics revealed dsProsβ1‐derived siRNA‐mediated mRNA cleavage events, mainly at uracil‐guanine and adenine‐adenine pairs. Proteasome inhibition via dsProsβ1 increased mitochondrial and cytoskeletal proteins while reducing translation‐related and mRNA‐binding proteins.
Doga Cedden, Gözde Güney, Michael Rostás, Stefan Scholten   +3 more
wiley   +1 more source

Carboxymethylcytosine is a natural base modification and a handle for bacteriophage DNA hypermodification. [PDF]

Nat Commun
Yang Q, Zhang L, Liang Y, Ma H, Song L, Luo L, Tan J, Hu Y, Ma K, Chen Y, Tong Y, Zhang C, Zhao S, Wang M, Zhang L, Wei Y, Zhang Y.   +16 more
europepmc   +1 more source

Potential of endophytic Beauveria bassiana against Coraebus (Coleoptera: Buprestidae) oak borers

Pest Management Science, EarlyView.
This study demonstrates that an endophytic, oak‐associated strain of Beauveria bassiana exhibits adaptations to Quercus plants and potential against Coraebus boring beetles, supported by distinctive biological traits. Abstract BACKGROUND Oak borers in the genus Coraebus, including the bark‐ and the wood‐boring beetles C. florentinus and C. undatus, are
Walaa Morda, Alessia Vinci, Andrea Lentini, Roberto Mannu, Maurizio Olivieri, Luca Ruiu   +5 more
wiley   +1 more source

An engineered yeast cytosine deaminase with improved catalytic activity and stability for macrophage-mediated enzyme/prodrug therapy. [PDF]

Commun Biol
Zheng J, Zhou J, Yung KWY, Hu Q, Lee MM, Chan MK.   +5 more
europepmc   +1 more source

Exploring the Fragmentation of Sodiated Species Involving Covalent‐Bond Cleavages for Metabolite Characterization

Rapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale Electrospray (ESI), the most popular desorption/ionization technique used in mass spectrometry‐based metabolomics, generates both protonated and deprotonated molecules, as well as adduct ions, sodium being the most frequent monoatomic cation entering their composition.
Annelaure Damont, Ekaterina Darii, Chenqin Cao, Anaïs Legrand, Alain Perret, Sylvain Dechaumet, Amina S. Woods, Christophe Junot, Jean‐Claude Tabet, François Fenaille   +9 more
wiley   +1 more source

Uncovering dormancy stage predictors in sweet cherry through DNA methylation and machine learning integration. [PDF]

Front Plant Sci
Saavedra GM, Povea P, Urra C, Gaete-Loyola J, Maldonado C, Almeida AM.   +5 more
europepmc   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Correction to 'mRNA turnover dynamics are affected by cell differentiation and loss of the cytosine methyltransferase Nsun2'. [PDF]

Nucleic Acids Res
europepmc   +1 more source