Metabolomic profiling of patients with lupus nephritis reveals unique metabolites that are modulated through type I interferon inhibition by anifrolumab treatment in a phase 2 trial. [PDF]
Gavin PG +18 more
europepmc +1 more source
This study explored a combined therapy of Brassica rapa L. polysaccharides and dexamethasone with an improved anti‐rheumatic and immunomodulatory effects, which also altered gut microbiome and gut barrier disruption in regulation of rheumatoid arthritis.
Hongkang Zhu +3 more
wiley +1 more source
Uncovering dormancy stage predictors in sweet cherry through DNA methylation and machine learning integration. [PDF]
Saavedra GM +5 more
europepmc +1 more source
Studies on Intermolecular Complex Formation. IV. Crystal Structure of Cytosine-Resorcylic acid 2:1 Complex monohydrate [PDF]
Chihiro Tamura, Sadao Sato, Tadashi Hata
openalex +1 more source
Advances in Detecting RNA Modifications Using Direct RNA Nanopore Sequencing
This review examines recent advances in Oxford Nanopore Technologies direct RNA sequencing, highlighting its expanding capacity to detect RNA modifications beyond m6A. It discusses computational frameworks and basecalling innovations that enable single‐nucleotide and single‐molecule resolution, explores co‐occurring modifications and their regulatory ...
Yaran Liu, Yang Li, Qiang Sun
wiley +1 more source
A ternary-code DNA methylome atlas of mouse tissues. [PDF]
Lee SM +12 more
europepmc +1 more source
Treatment of acute myeloid leukemia of adults with cytosine arabinoside in combination with 6-mercaptopurine [PDF]
John G. Buchanan +4 more
openalex +1 more source
Established a C9ORF72 ALS microglia and motor neuron coculture model. Identified an altered inflammatory signature in C9ORF72 ALS microglia. Single‐cell RNA sequencing detected the removal of an LPS responsive microglia subpopulation. ABSTRACT Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disorder involving multiple cell types in ...
Yujing Gao +9 more
wiley +1 more source
Global DNA-methylation in quantitative epigenetics: orbitrap mass spectrometry. [PDF]
Otto JFM +5 more
europepmc +1 more source

