Results 21 to 30 of about 136,619 (315)
Enzymatic approaches for profiling cytosine methylation and hydroxymethylation
Molecular Metabolism, 2022 Background: In mammals, modifications to cytosine bases, particularly in cytosine-guanine (CpG) dinucleotide contexts, play a major role in shaping the epigenome.
Tong Wang +2 more
doaj +1 more source
Ureido cytosine and cytosine-containing acrylic copolymers
Polymer Chemistry, 2016 Ureido-cytosine pendant groups contributed to random acrylic copolymers with enhanced thermomechanical performance, well-defined morphologies, and reduced water uptake.
Keren Zhang +6 more
openaire +2 more sources
Consecutive Silver(I) Ion Incorporation into Oligonucleotides containing Cytosine‐Cytosine Mispairs [PDF]
ChemPlusChem, 2020 AbstractInvited for this month's cover is the group of Prof. Heinz‐Bernhard Kraatz from the University of Toronto, Canada. The cover picture shows the consecutive incorporation of AgI ions into a DNA duplex containing adjacent C−C mispairs. Read the full text of the article at 10.1002/cplu.202000607.
M. Nur Hossain +2 more
openaire +3 more sources
Evaluating Relative Retention of Polar Stationary Phases in Hydrophilic Interaction Chromatography
Separations, 2019 A large number of polar stationary phases with diverse chemistry have been developed for various applications in hydrophilic interaction chromatography (HILIC).
Yong Guo, Nidhi Bhalodia, Bassel Fattal
doaj +1 more source
A mutant of uracil DNA glycosylase that distinguishes between cytosine and 5-methylcytosine. [PDF]
PLoS ONE, 2014 We demonstrate that a mutant of uracil DNA glycosylase (N123D:L191A) distinguishes between cytosine and methylcytosine. Uracil DNA glycosylase (UDG) efficiently removes uracil from DNA in a reaction in which the base is flipped into the enzyme's active ...
Scott T Kimber, Tom Brown, Keith R Fox
doaj +1 more source
Factors Influencing the Nitrogen-Source Dependent Flucytosine Resistance in Cryptococcus Species
mBio, 2023 Flucytosine (5-FC) is an antifungal agent commonly used for treatment of cryptococcosis and several other systemic mycoses. In fungi, cytosine permease and cytosine deaminase are known major players in flucytosine resistance by regulating uptake and ...
Dong-Hoon Yang +3 more
doaj +1 more source
eLife, 2021 Shotgun metagenomic sequencing is a powerful approach to study microbiomes in an unbiased manner and of increasing relevance for identifying novel enzymatic functions.
Weiwei Yang +9 more
doaj +1 more source
South Asian Journal of Cancer, 2016 Aim: Lung cancer is considered to be the most common cancer in the world. In humans, about 50% or more cancers have a mutated tumor suppressor p53 gene thereby resulting in accumulation of p53 protein and losing its function to activate the target genes ...
Rashid Mir +9 more
doaj +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Frontiers in Genetics, 2015 DNA cytosine methylation is a widespread epigenetic mechanism in eukaryotes, and plant genomes commonly are densely methylated. Genomic methylation can be associated with functional consequences such as mutational events, genomic instability or altered ...
Conchita eAlonso +3 more
doaj +1 more source