Results 141 to 150 of about 62,191 (286)

The Role of Oxidative Stress in Periodontitis

Journal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon, Francesca Giampieri, Beatriz Bullon, Maurizio Battino   +3 more
wiley   +1 more source

Histone deacetylation and cytosine methylation compartmentalize heterochromatic regions in the genome organization of <i>Neurospora crassa</i>. [PDF]

Proc Natl Acad Sci U S A, 2023
Scadden AW, Graybill AS, Hull-Crew C, Lundberg TJ, Lande NM, Klocko AD.   +5 more
europepmc   +1 more source

Epigenetic Regulation in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
The aim of this narrative literature review was to identify epigenetic marks associated with periodontitis and to place them in a biological context. The literature was reviewed based on pre‐defined criteria. Cell type specific chromatin and mRNA modifications were included.
Henrik Dommisch, Arne Sönke Schäfer, Denica Kuzmanova, Dominique S. Michaud   +3 more
wiley   +1 more source

Cytosine methylation flags mitochondrial RNA for degradation

Trends in Biochemical Sciences
Mitochondrial double-stranded RNA (dsRNA) can form spontaneously in mitochondria, blocking mitochondrial gene expression and triggering an immune response. A recent study by Kim, Tan, et al. identified a safeguard mechanism in which NOP2/Sun RNA methyltransferase 4 (NSUN4)-mediated RNA methylation (m5C) recruits the RNA degradation machinery to prevent
Emeline Recazens, Alexis A. Jourdain
openaire   +3 more sources

Accurate Detection of Methylated Cytosine in Complex Methylation Landscapes

, 2016
Monitoring DNA methylation can be a useful biomarker for disease diagnosis and prognosis. However, monitoring the methylation status of a specific cytosine biomarker is often confounded by heterogeneous peripheral DNA methylation.
Ramkumar Palanisamy (649144), Ashley R. Connolly (1935241), Matt Trau (472531)   +2 more
core   +1 more source

Beyond Deterministic Fetal Programming: Intrauterine Exposures and the Multifactorial Origins of Adiposity

Obesity Reviews, EarlyView.
ABSTRACT Excess adiposity is not a recently developed problem but has existed since at least the upper Paleolithic, allowing evolutionary selection pressures to adapt the physiology of the pregnant woman and the feto‐placental unit for maternal and fetal protection.
Gernot Desoye, Ursula Hiden, Evelyn Jantscher‐Krenn, Herbert Fluhr, Jonathan C. Wells, Sonja Entringer, Mireille N. M. van Poppel   +6 more
wiley   +1 more source

G-quadruplex formation at human DAT1 gene promoter: Effect of cytosine methylation. [PDF]

Biochem Biophys Rep, 2023
Nain N, Singh A, Khan S, Kukreti S.
europepmc   +1 more source

DNA Methylation Shapes Seed‐Borne Microbiome and Proteome Responses During Early Maize‐Beneficial Bacteria Interactions

Plant, Cell &Environment, EarlyView.
ABSTRACT Microorganism and plant interactions are crucial for development and environmental adaptation. Plant growth promoting bacteria enhance agricultural productivity in a sustainable manner, while epigenetic modifications such as DNA methylation regulate gene expression and adaptive responses.
Pedro Igor Zocateli, Geovanna Vitória Olímpio, Felipe Astolpho de Almeida, Letícia Oliveira da Rocha, Diego Vinicius de Sena Martins, Sara Sangi, Fábio Lopes Olivares, Elyabe Monteiro de Matos, Juliana Siqueira, Lyderson Facio Viccini, Roberta Pena da Paschoa, Vanildo Silveira, Clícia Grativol   +12 more
wiley   +1 more source

Single-cytosine methylation at W-boxes repels binding of WRKY transcription factors through steric hindrance. [PDF]

Plant Physiol, 2023
Charvin M, Halter T, Blanc-Mathieu R, Barraud P, Aumont-Nicaise M, Parcy F, Navarro L.   +6 more
europepmc   +1 more source

DNA Cytosine Methylation and Hydroxymethylation at the Borders [PDF]

Epigenomics, 2014
Melanie, Ehrlich, Kenneth C, Ehrlich
openaire   +2 more sources