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Cytosine methylation mediates sexual conflict
Trends in Genetics, 2003Transposons are infectious agents in sexual populations and can go to fixation even if they reduce the fitness of the host. Sexual hosts are therefore under selective pressure to evolve defensive functions that relieve the fitness penalty imposed by transposons.
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Methylation of cytosine influences the DNA structure
1993In the past decade it has become increasingly clear that DNA has the potential to adopt a variety of unusual secondary structures which deviate from the classical right-handed B-DNA form. Intrinsic properties of the DNA molecule (primary base sequence and base modifications, degree of supercoiling) determine whether such an unusual structure is ...
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Biochemistry, 1993
Previous spectroscopic studies demonstrated that the oligodeoxynucleotide d(CGC G3 GCG) undergoes a reversible cation-dependent transition between Watson-Crick (WC) hairpin and parallel-stranded "G-DNA" quadruplex structures [Hardin, C.C., Watson, T., Corregan, M., & Bailey, C. (1992) Biochemistry 31, 833-841].
C C, Hardin +3 more
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Previous spectroscopic studies demonstrated that the oligodeoxynucleotide d(CGC G3 GCG) undergoes a reversible cation-dependent transition between Watson-Crick (WC) hairpin and parallel-stranded "G-DNA" quadruplex structures [Hardin, C.C., Watson, T., Corregan, M., & Bailey, C. (1992) Biochemistry 31, 833-841].
C C, Hardin +3 more
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The Expanding View of Cytosine Methylation
2008We are currently in an era of increased interest in the role of the epigenome in normal cellular physiology and its role in human disease. Part of this increased interest is driven by new technologies that have allowed us to gain insights never previously possible.
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Biological aspects of cytosine methylation in eukaryotic cells
Experientia, 1991The existence in eukaryotes of a fifth base, 5-methylcytosine, and of tissue-specific methylation patterns have been known for many years, but except for a general association with inactive genes and chromatin the exact function of this DNA modification has remained elusive.
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Cytosine methylation The pros and cons of DNA methylation
Current Biology, 1993T H, Bestor, A, Coxon
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Inheritance of Cytosine Methylation
Journal of Cellular Physiology, 2016Desiree Tillo +2 more
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