Results 161 to 170 of about 62,191 (286)

Enzymatic approaches for profiling cytosine methylation and hydroxymethylation. [PDF]

Mol Metab, 2022
Wang T, Loo CE, Kohli RM.
europepmc   +1 more source

BDNF gene methylation in brain of suicide subjects

, 2009
: Brain-derived neurotrophic factor (BDNF) plays a pivotal role in the pathophysiology of suicidal behaviour and BDNF levels are decreased in brain and plasma of suicide subjects.
Keller, Simona
core  

Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing

The Journal of Physiology, EarlyView.
Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda, Julijana Ivanovska, Dwayne Mascarenhas, Jeffrey Antwi, Atefeh Mohammadi, Bonny Jasani   +5 more
wiley   +1 more source

DNA Methylation: Its Role and Interaction with Epigenetic Modifications in Cancer

Progress in Microbes and Molecular Biology
DNA methylation is an epigenetic mark involving the addition of a methyl group to DNA, particularly at cytosine residues. This methylation plays an important role in regulating gene expression through direct gene repression or through the control of ...
Nasreddine El Omari, Saad Bakrim, Mohamed Bakha, Abdelaali Balahbib, Abdelhakim Bouyahya, Chrismawan Ardianto, Long Chiau Ming, Hooi Leng Ser   +7 more
doaj  

Rapid and Efficient Spatiotemporal Monitoring of Normal and Aberrant Cytosine Methylation within Intact Zebrafish Embryos. [PDF]

J Vis Exp, 2022
Avila-Barnard S, Volz DC.
europepmc   +1 more source

Identification of Crucial Drug Targets and Pathways to Reprogram Drug Resistance Through Epigenetic Modulation in Advanced Lung Cancer Using Integrated Bioinformatics Approach

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Resistance to chemotherapy, which is demonstrated in almost every patient with advanced‐stage lung cancer (ALC), underscores an urgent need to unravel the underlying molecular mechanisms and identify novel strategies to overcome drug resistance. In the present study, an attempt was made to identify epigenetic targets and modulators that can be
Okibur Rahman, Mossammat Rima Akter, Nur Alam   +2 more
wiley   +1 more source

Toward a base-resolution panorama of the in vivo impact of cytosine methylation on transcription factor binding. [PDF]

Genome Biol, 2022
Hernandez-Corchado A, Najafabadi HS.
europepmc   +1 more source

Changes in DNA methylation–based aging predicts brain damage and dementia and reflects life‐course cardiovascular risk

Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract INTRODUCTION There is well‐established evidence showing an association between accelerated biological aging (BA) and brain pathology. However, it remains unclear whether dynamic change in BA during adulthood is directly associated with brain health or primarily reflects cumulative life‐course environmental and lifestyle exposures.
Nigus Gebremedhin Asefa, Jorge Martinez Romero, Yi‐Han Hu, Zhiguang Li, Osorio Meirelles, Djassinabaye Mbangdadji, May A. Beydoun, Sigurdur Sigurdsson, Valborg Gudmundsdottir, Thor Aspelund, Vilmundur Gudnason, Lenore Launer   +11 more
wiley   +1 more source

DNA cytosine methylation at the lexA promoter of Escherichia coli is stationary phase specific. [PDF]

G3 (Bethesda), 2022
Lewis EB, Chen E, Culyba MJ.
europepmc   +1 more source

RNA Modifications in Tumor Microenvironment: A New Dimension for Cancer Treatment

MedComm, Volume 7, Issue 7, July 2026.
Tumor initiation and progression depend on a supportive and highly heterogeneous tumor microenvironment (TME). RNA modifications regulate signaling pathways and cytokine networks that shape TME dynamics, facilitating interactions between cancer cells and noncancerous stromal cells, and ultimately promoting immune evasion and tumor progression ...
Qiwen Li, Yating Sun, Shuibin Lin, Quan Yuan   +3 more
wiley   +1 more source