DMRU: generative deep learning to unravel condition-specific cytosine methylation in plants. [PDF]
Gupta S +4 more
europepmc +1 more source
Epigenetic Aging in Brain Tissue of the Self‐Fertilizing Vertebrate, Kryptolebias marmoratus
Using the self‐fertilizing vertebrate Kryptolebias marmoratus, we developed an epigenetic clock from brain tissue that predicts chronological age with high accuracy, demonstrating that DNA methylation changes consistently with age even in the near absence of genetic variation. The 40 age‐associated CpG sites identified map to genes with conserved roles
Justine Bélik, Frédéric Silvestre
wiley +1 more source
Repressive Cytosine Methylation is a Marker of Viral Gene Transfer Across Divergent Eukaryotes. [PDF]
Sarre LA +4 more
europepmc +1 more source
Streptomyces coelicolor: DNA cytosine methylation and differentiation [PDF]
DNA methylation is an epigenetic modification regulating many aspects of biological processes. DNA cytosine methylation plays mainly a regulatory role in chromatin organization, genome maintenance and gene expression in eukaryotes, while its role in ...
PISCIOTTA, Annalisa
core
Site-Specific Changes in Cytosine Methylation in Promoters of the Genes Encoding the Membrane Subunits of Succinate Dehydrogenase During Germination of Maize Seeds. [PDF]
Fedorin DN +2 more
europepmc +1 more source
Mechanisms underlying epigenetic gene silencing in maize [PDF]
Higher organisms can regulate gene expression through changes in epigenetic marks present on the genome. However, how this regulation takes place in organisms with highly repetitive/complex genomes is not well understood.
Schafer, David Gerald
core
Roles of histone lysine methylation in neurodevelopment and related disorders
This graphical abstract centers on the theme of dynamic balance and systematically outlines the role of histone lysine methylation in neurodevelopment and related disorders. The figure first presents two key classes of regulators that control this balance—“writers” and “erasers”—and then indicates how interactions among different epigenetic ...
Yun Chen +3 more
wiley +1 more source
Label-Free Surface-Enhanced Raman Scattering for Genomic DNA Cytosine Methylation Reading. [PDF]
Alom KM +4 more
europepmc +1 more source
Integrating polygenic and methylation risk scores for pleural mesothelioma risk stratification
What's new? Asbestos exposure is a major risk factor for pleural mesothelioma (PM). Most asbestos‐exposed individuals do not develop PM, suggesting that it arises from a complex interplay between environmental and genetic factors. This study examined the utility of polygenic risk scores (PRS) and methylation risk scores (MRS) in incorporating genetic ...
Khadija Sana Hafeez +26 more
wiley +1 more source

