Results 221 to 230 of about 42,535 (254)
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Oligomerization of cytosine-containing nucleotide analogs in aqueous solution
Journal of Molecular Evolution, 1990Bisphosphoimidazolides of 2'-deoxycytidine and of its acyclic analog C can be oligomerized in aqueous solution in the presence of Mn(II). Under certain conditions, a range of products extending to at least the 20mer can be obtained. These products are of interest as possible templates for oligomerization of the complementary monomers.
J, Visscher, A W, Schwartz
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Modification of cytosine nucleotides: preparation and metalation of a furyl derivative
Bioinorganic Chemistry, 1978Abstract O-Furfurylhydroxylamine (FHA) was synthesized and found to react with cytosine derivatives in the presence of sodium bisulfite. Conversion of cytidine to sodiumN4-furfuryloxy-5,6-dihydrocytidine-6-sulfonate by 1 M FHA in aqueous methanolic or ethanolic sodium bisulfite took place with a half-life of 11 min at pH 5 and room temperature ...
Seth D. Rose, Michael Beer
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Org. Biomol. Chem., 2004
A new series of cytosine-substituted metalloporphyrin conjugates (containing Co(II) and Zn(II) as the coordinated metals) were designed and investigated as nucleotide receptors in PVC-membrane-based ion-selective electrodes under neutral conditions. The potentiometric results indicate that these systems, in particular the Co(II)-containing complex, may
Vladimír, Král +3 more
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A new series of cytosine-substituted metalloporphyrin conjugates (containing Co(II) and Zn(II) as the coordinated metals) were designed and investigated as nucleotide receptors in PVC-membrane-based ion-selective electrodes under neutral conditions. The potentiometric results indicate that these systems, in particular the Co(II)-containing complex, may
Vladimír, Král +3 more
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The effect of cytosine- and guanine nucleotides on the isolated frog heart
Pfl�gers Archiv f�r die Gesamte Physiologie des Menschen und der Tiere, 19641. The effect of the cytosine- and guanine nucleotides on hypodynamic frog hearts was investigated. 2.
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Major oxidative products of cytosine are substrates for the nucleotide incision repair pathway
DNA Repair, 2007Most common point mutations occurring spontaneously or induced by ionizing radiation are C-->T transitions implicating cytosine as the target. Oxidative cytosine derivatives are the most abundant and mutagenic DNA damage induced by oxidative stress. Base excision repair (BER) pathway initiated by DNA glycosylases is thought to be the major pathway for ...
Stéphane, Daviet +6 more
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Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1980
An azo pyrimidine that induces the polymerization of 1-glyceryl methacrylate has been prepared. 1-Glyceryl methacrylate contains substituent glycol groups for binding heavy atoms for subsequent electron microscopic studies. Oxodation of 1-methyl N4-ureidocytosine (compound 1A) with N-bromosuccinimide produced 4-aminocarbonylazo-2-pyrimidinone (compound
G L, Brown, R F, Hartman, S D, Rose
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An azo pyrimidine that induces the polymerization of 1-glyceryl methacrylate has been prepared. 1-Glyceryl methacrylate contains substituent glycol groups for binding heavy atoms for subsequent electron microscopic studies. Oxodation of 1-methyl N4-ureidocytosine (compound 1A) with N-bromosuccinimide produced 4-aminocarbonylazo-2-pyrimidinone (compound
G L, Brown, R F, Hartman, S D, Rose
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ChemBioChem, 2006
AbstractBiosynthesis of the antifungal agent blasticidin S in Streptomyces griseochromogenes requires the formation of free cytosine. The blsM gene in the blasticidin S gene cluster is predicted to encode a protein that has sequence homology with several nucleoside transferases.
Laura L, Grochowski, T Mark, Zabriskie
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AbstractBiosynthesis of the antifungal agent blasticidin S in Streptomyces griseochromogenes requires the formation of free cytosine. The blsM gene in the blasticidin S gene cluster is predicted to encode a protein that has sequence homology with several nucleoside transferases.
Laura L, Grochowski, T Mark, Zabriskie
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Single Nucleotide Analysis of Cytosine Methylation by Whole‐Genome Shotgun Bisulfite Sequencing
Current Protocols in Molecular Biology, 2012AbstractUnlike other methods to assess methylation, whole‐genome shotgun bisulfite sequencing is used to generate quantitative genome‐wide methylation profiles at single‐nucleotide resolution. As described in this unit, this method allows for the quantitative measurement of methylation at each cytosine base by treatment of genomic DNA with sodium ...
Michelle D, Johnson +3 more
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Nanotechnology, 2004
Langmuir monolayers of diacetylene lipids with a cytosinyl head-group (PDC), mixed with an alcohol derivative of the same lipid (PDOH), were formed on water and on guanosine solution, and were UV polymerized in situ. Brewster angle microscopy (BAM), atomic force microscopy (AFM) and visible light absorption spectroscopy were performed on the monolayers.
Jie Chen, Amir Berman
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Langmuir monolayers of diacetylene lipids with a cytosinyl head-group (PDC), mixed with an alcohol derivative of the same lipid (PDOH), were formed on water and on guanosine solution, and were UV polymerized in situ. Brewster angle microscopy (BAM), atomic force microscopy (AFM) and visible light absorption spectroscopy were performed on the monolayers.
Jie Chen, Amir Berman
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PHOTOCHEMISTRY OF CYTOSINE NUCLEOSIDES AND NUCLEOTIDES—III. MONO‐ AND DI‐ METHYLAMINO ANALOGUES
Photochemistry and Photobiology, 1962SummaryAn investigation has been made of the photochemical (2537 A) behaviour in aqueous medium of mono‐ and dialkylamino substituted cytosines, their nucleosides and nucleotides. The principal reaction in all instances is photohydration, the photoproducts being the 5‐hydro‐6‐hydroxy derivatives of the parent compounds, as for cytosine analogues with a
M. Fikus, K. L. Wierzchowski, D. Shugar
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