Results 51 to 60 of about 196,328 (291)

Cytoskeletal proteins and resident flora

, 2002
Recent observations demonstrate that enteropathogenetic and enterohaemorrhagic bacteria, as well as other non enteropathogenetic bacteria (Listeria, Coxiella Burnetii), may subvert the host cell cytoskeleton.
PALLONE, FRANCESCO, PALMIERI, GIAMPIERO, Del Vecchio Blanco, G, Colantoni, A, DEL VECCHIO BLANCO, GIOVANNA, BIANCONE, LIVIA, MONTELEONE, IVAN, SPAGNOLI, LUIGI GIUSTO, Palmieri, G, COLANTONI, ALFREDO, Tonelli, F, Monteleone, I, Biancone, L, Lombardi, A, Pallone, F, Vavassori, P, Spagnoli, L   +16 more
core   +1 more source

Special issue on 'Cytoskeletal proteins in health and neurodegenerative disease' [PDF]

, 2016
The cytoskeleton is the major intracellular structure that determines the morphology of neurons and maintains their structural integrity. It is therefore not surprising that a disturbance of cytoskeletal structure and functionunderlies many ...
Goetz, Juergen, Brandt, Roland
core   +1 more source

SHIP2 interaction with the cytoskeletal protein Vinexin [PDF]

The FEBS Journal, 2005
The src homology 2 (SH2) domain‐containing inositol 5‐phosphatase 2 (SHIP2) catalyses the dephosphorylation of phosphatidylinositol 3,4,5‐trisphosphate [PtdIns(3,4,5)P3] to phosphatidylinositol 3,4‐bisphosphate [PtdIns(3,4)P2]. We report the identification of the cytoskeletal protein Vinexin as a protein interacting with SHIP2.
Paternotte, Nathalie, Zhang, Jing, Vandenbroere, Isabelle, Backers, Katrien, Blero, Daniel, Kioka, Noriyuki, Vanderwinden, Jean-Marie, Pirson, Isabelle, Erneux, Christophe   +8 more
openaire   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

IQGAP1 interacts with components of the slit diaphragm complex in podocytes and is involved in podocyte migration and permeability in vitro.

PLoS ONE, 2012
IQGAP1 is a scaffold protein that interacts with proteins of the cytoskeleton and the intercellular adhesion complex. In podocytes, IQGAP1 is associated with nephrin in the glomerular slit diaphragm (SD) complex, but its role remains ill-defined. In this
Claire Rigothier, Patrick Auguste, Gavin I Welsh, Sébastien Lepreux, Colette Deminière, Peter W Mathieson, Moin A Saleem, Jean Ripoche, Christian Combe   +8 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Autoantibodies against cytoskeletal proteins in rheumatoid arthritis

, 2002
We determined the prevalence and antigenic specificity of autoantibodies against cytoskeletal proteins in patients affected with various autoimmune diseases.
Aggarwal, A., Shrivastav, M., Mittal, B., Misra, R.   +3 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

RNA-dependent association with myosin IIA promotes F-actin-guided trafficking of the ELAV-like protein HuR to polysomes

, 2013
The role of the mRNA-binding protein human antigen R (HuR) in stabilization and translation of AU-rich elements (ARE) containing mRNAs is well established.
Eberhardt, Wolfgang, Schulz, Sebastian, Pfeilschifter, Josef, Doller, Anke   +3 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source