Results 31 to 40 of about 196,328 (291)
New Frontiers for the Cytoskeletal Protein LASP1 [PDF]
Frontiers in Oncology, 2018 In the recent two decades, LIM and SH3 protein 1 (LASP1) has been developed from a simple actin-binding structural protein to a tumor biomarker and subsequently to a complex, nuclear transcriptional regulator. Starting with a brief historical perspective, this review will mainly compare and contrast LASP1 and LASP2 from the angle of the newest data and
Butt, Elke, Raman, Dayanidhi
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An ongoing role for structural sarcomeric components in maintaining Drosophila melanogaster muscle function and structure. [PDF]
PLoS ONE, 2014 Animal muscles must maintain their function while bearing substantial mechanical loads. How muscles withstand persistent mechanical strain is presently not well understood.
Alexander D Perkins, Guy Tanentzapf
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The spectrin cytoskeleton is crucial for adherent and invasive bacterial pathogenesis. [PDF]
PLoS ONE, 2011 Various enteric bacterial pathogens target the host cell cytoskeletal machinery as a crucial event in their pathogenesis. Despite thorough studies detailing strategies microbes use to exploit these components of the host cell, the role of the spectrin ...
Tyson Ruetz +2 more
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The Plasma Membrane Potential and the Organization of the Actin Cytoskeleton of Epithelial Cells
International Journal of Cell Biology, 2012 The establishment and maintenance of the polarized epithelial phenotype require a characteristic organization of the cytoskeletal components. There are many cellular effectors involved in the regulation of the cytoskeleton of epithelial cells.
Silvia Chifflet, Julio A. Hernández
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Catching a Walker in the Act—DNA Partitioning by ParA Family of Proteins
Frontiers in Microbiology, 2022 Partitioning the replicated genetic material is a crucial process in the cell cycle program of any life form. In bacteria, many plasmids utilize cytoskeletal proteins that include ParM and TubZ, the ancestors of the eukaryotic actin and tubulin ...
Dipika Mishra +3 more
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Connecting two arrays: The emerging role of actin-microtubule cross-linking motor proteins
Frontiers in Plant Science, 2015 The cytoskeleton of plant cells, consisting of actin filaments (AFs) and microtubules (MTs), is a central structure for various intracellular processes, such as cell division, isotropic and polar growth, vesicle transport, cell shape and morphogenesis ...
René eSchneider, Staffan ePersson
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Biomedicines, 2022 Glioblastoma is the deadliest malignant brain tumor. Its location behind the blood–brain barrier (BBB) presents a therapeutic challenge by preventing effective delivery of most chemotherapeutics.
Brittanie R. Partridge +10 more
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Cytoskeletal proteins: The evolution of cell division [PDF]
Current Biology, 1998 The prokaryotic cell division protein FtsZ and eukaryotic tubulin have been shown to have very similar structures and are most likely homologs. The evolutionary transition from FtsZ to tubulin could provide a window into the transition from prokaryotic cells to eukaryotic cells.
Faguy, David M., Doolittle, W.Ford
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Regulation of store-operated Ca2+ entry by Septins
Frontiers in Cell and Developmental Biology, 2016 The mechanism of store-operated Ca2+entry (SOCE) brings extracellular Ca2+ into cells after depletion of intracellular Ca2+ stores. Regulation of Ca2+ homeostasis by SOCE helps control various intracellular signaling functions in both non-excitable and ...
Bipan Kumar Deb, Gaiti Hasan
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Cytoskeletal Protein Variants Driving Atrial Fibrillation: Potential Mechanisms of Action
Cells, 2022 The most common clinical tachyarrhythmia, atrial fibrillation (AF), is present in 1–2% of the population. Although common risk factors, including hypertension, diabetes, and obesity, frequently underlie AF onset, it has been recognized that in 15% of the
Stan W. van Wijk +4 more
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