The Emerging Role of the Cytoskeleton in Chromosome Dynamics
Chromosomes underlie a dynamic organization that fulfills functional roles in processes like transcription, DNA repair, nuclear envelope stability, and cell division.
Maya Spichal, Emmanuelle Fabre
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Sensor potency of the moonlighting enzyme-decorated cytoskeleton [PDF]
Background: There is extensive evidence for the interaction of metabolic enzymes with the eukaryotic cytoskeleton. The significance of these interactions is far from clear.
Amar Patrick +5 more
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Vimentin filaments are assembled from a soluble precursor in avian erythroid cells [PDF]
The synthesis and assembly of vimentin was studied in erythroid cells from 10-d-old chicken embryos. After various periods of [35S]methionine incorporation, cells were lysed in a Triton X-100-containing buffer and separated into a soluble and an ...
Blikstad, Ingrid, Lazarides, Elias
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Myofibroblasts, specialized cells that play important roles in wound healing and fibrosis, can develop from epithelial cells through an epithelial-mesenchymal transition (EMT).
Joseph W O'Connor, Esther W Gomez
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Cytoskeletal disorganization underlies PABPN1-mediated myogenic disability
Muscle wasting and atrophy are regulated by multiple molecular processes, including mRNA processing. Reduced levels of the polyadenylation binding protein nucleus 1 (PABPN1), a multifactorial regulator of mRNA processing, cause muscle atrophy.
Cyriel Sebastiaan Olie +10 more
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NEURONIC SYSTEM INSIDE NEURONS: MOLECULAR BIOLOGY AND BIOPHYSICS OF NEURONAL MICROTUBULES [PDF]
Neurons are highly specialized cells that input, process, store and output information. Interneuronal communication is achieved in four basic ways: (i) Ca2+ evoked exocytosis with chemical neurotransmission, (ii) gap junction electrotonic coupling, (iii)
Georgiev, Danko +2 more
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Processes underlying the nutritional programming of embryonic development by iron deficiency in the rat [PDF]
Peer reviewedPublisher ...
Gambling, Lorraine +5 more
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An ongoing role for structural sarcomeric components in maintaining Drosophila melanogaster muscle function and structure. [PDF]
Animal muscles must maintain their function while bearing substantial mechanical loads. How muscles withstand persistent mechanical strain is presently not well understood.
Alexander D Perkins, Guy Tanentzapf
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The spectrin cytoskeleton is crucial for adherent and invasive bacterial pathogenesis. [PDF]
Various enteric bacterial pathogens target the host cell cytoskeletal machinery as a crucial event in their pathogenesis. Despite thorough studies detailing strategies microbes use to exploit these components of the host cell, the role of the spectrin ...
Tyson Ruetz +2 more
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The Plasma Membrane Potential and the Organization of the Actin Cytoskeleton of Epithelial Cells
The establishment and maintenance of the polarized epithelial phenotype require a characteristic organization of the cytoskeletal components. There are many cellular effectors involved in the regulation of the cytoskeleton of epithelial cells.
Silvia Chifflet, Julio A. Hernández
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