Results 21 to 30 of about 291,933 (344)

The Emerging Role of the Cytoskeleton in Chromosome Dynamics

open access: yesFrontiers in Genetics, 2017
Chromosomes underlie a dynamic organization that fulfills functional roles in processes like transcription, DNA repair, nuclear envelope stability, and cell division.
Maya Spichal, Emmanuelle Fabre
doaj   +1 more source

Sensor potency of the moonlighting enzyme-decorated cytoskeleton [PDF]

open access: yes, 2013
Background: There is extensive evidence for the interaction of metabolic enzymes with the eukaryotic cytoskeleton. The significance of these interactions is far from clear.
Amar Patrick   +5 more
core   +4 more sources

Vimentin filaments are assembled from a soluble precursor in avian erythroid cells [PDF]

open access: yes, 1983
The synthesis and assembly of vimentin was studied in erythroid cells from 10-d-old chicken embryos. After various periods of [35S]methionine incorporation, cells were lysed in a Triton X-100-containing buffer and separated into a soluble and an ...
Blikstad, Ingrid, Lazarides, Elias
core   +3 more sources

Cell adhesion and shape regulate TGF-beta1-induced epithelial-myofibroblast transition via MRTF-A signaling.

open access: yesPLoS ONE, 2013
Myofibroblasts, specialized cells that play important roles in wound healing and fibrosis, can develop from epithelial cells through an epithelial-mesenchymal transition (EMT).
Joseph W O'Connor, Esther W Gomez
doaj   +1 more source

Cytoskeletal disorganization underlies PABPN1-mediated myogenic disability

open access: yesScientific Reports, 2020
Muscle wasting and atrophy are regulated by multiple molecular processes, including mRNA processing. Reduced levels of the polyadenylation binding protein nucleus 1 (PABPN1), a multifactorial regulator of mRNA processing, cause muscle atrophy.
Cyriel Sebastiaan Olie   +10 more
doaj   +1 more source

NEURONIC SYSTEM INSIDE NEURONS: MOLECULAR BIOLOGY AND BIOPHYSICS OF NEURONAL MICROTUBULES [PDF]

open access: yes, 2004
Neurons are highly specialized cells that input, process, store and output information. Interneuronal communication is achieved in four basic ways: (i) Ca2+ evoked exocytosis with chemical neurotransmission, (ii) gap junction electrotonic coupling, (iii)
Georgiev, Danko   +2 more
core   +1 more source

An ongoing role for structural sarcomeric components in maintaining Drosophila melanogaster muscle function and structure. [PDF]

open access: yesPLoS ONE, 2014
Animal muscles must maintain their function while bearing substantial mechanical loads. How muscles withstand persistent mechanical strain is presently not well understood.
Alexander D Perkins, Guy Tanentzapf
doaj   +1 more source

The spectrin cytoskeleton is crucial for adherent and invasive bacterial pathogenesis. [PDF]

open access: yesPLoS ONE, 2011
Various enteric bacterial pathogens target the host cell cytoskeletal machinery as a crucial event in their pathogenesis. Despite thorough studies detailing strategies microbes use to exploit these components of the host cell, the role of the spectrin ...
Tyson Ruetz   +2 more
doaj   +1 more source

The Plasma Membrane Potential and the Organization of the Actin Cytoskeleton of Epithelial Cells

open access: yesInternational Journal of Cell Biology, 2012
The establishment and maintenance of the polarized epithelial phenotype require a characteristic organization of the cytoskeletal components. There are many cellular effectors involved in the regulation of the cytoskeleton of epithelial cells.
Silvia Chifflet, Julio A. Hernández
doaj   +1 more source

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