New Frontiers for the Cytoskeletal Protein LASP1 [PDF]
Frontiers in Oncology, 2018 In the recent two decades, LIM and SH3 protein 1 (LASP1) has been developed from a simple actin-binding structural protein to a tumor biomarker and subsequently to a complex, nuclear transcriptional regulator. Starting with a brief historical perspective, this review will mainly compare and contrast LASP1 and LASP2 from the angle of the newest data and
Butt, Elke, Raman, Dayanidhi
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The apical submembrane cytoskeleton participates in the organization of the apical pole in epithelial cells [PDF]
, 1997 In a previous publication (Rodriguez, M.L., M. Brignoni, and P.J.I. Salas. 1994. J. Cell Sci. 107: 3145-3151), we described the existence of a terminal web-like structure in nonbrush border cells, which comprises a specifically apical cytokeratin ...
Ana L. Viciana +14 more
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The Emerging Role of the Cytoskeleton in Chromosome Dynamics
Frontiers in Genetics, 2017 Chromosomes underlie a dynamic organization that fulfills functional roles in processes like transcription, DNA repair, nuclear envelope stability, and cell division.
Maya Spichal, Emmanuelle Fabre
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SILAC-based proteomic quantification of chemoattractant-induced cytoskeleton dynamics on a second to minute timescale [PDF]
, 2014 Cytoskeletal dynamics during cell behaviours ranging from endocytosis and exocytosis to cell division and movement is controlled by a complex network of signalling pathways, the full details of which are as yet unresolved.
Sobczyk, Grzegorz J. +2 more
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PLoS ONE, 2013 Myofibroblasts, specialized cells that play important roles in wound healing and fibrosis, can develop from epithelial cells through an epithelial-mesenchymal transition (EMT).
Joseph W O'Connor, Esther W Gomez
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Cytoskeletal disorganization underlies PABPN1-mediated myogenic disability
Scientific Reports, 2020 Muscle wasting and atrophy are regulated by multiple molecular processes, including mRNA processing. Reduced levels of the polyadenylation binding protein nucleus 1 (PABPN1), a multifactorial regulator of mRNA processing, cause muscle atrophy.
Cyriel Sebastiaan Olie +10 more
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An ongoing role for structural sarcomeric components in maintaining Drosophila melanogaster muscle function and structure. [PDF]
PLoS ONE, 2014 Animal muscles must maintain their function while bearing substantial mechanical loads. How muscles withstand persistent mechanical strain is presently not well understood.
Alexander D Perkins, Guy Tanentzapf
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RNA-dependent association with myosin IIA promotes F-actin-guided trafficking of the ELAV-like protein HuR to polysomes [PDF]
, 2013 The role of the mRNA-binding protein human antigen R (HuR) in stabilization and translation of AU-rich elements (ARE) containing mRNAs is well established.
Eberhardt, Wolfgang +3 more
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The spectrin cytoskeleton is crucial for adherent and invasive bacterial pathogenesis. [PDF]
PLoS ONE, 2011 Various enteric bacterial pathogens target the host cell cytoskeletal machinery as a crucial event in their pathogenesis. Despite thorough studies detailing strategies microbes use to exploit these components of the host cell, the role of the spectrin ...
Tyson Ruetz +2 more
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Plasmid Segregation: A New Class of Cytoskeletal Proteins Emerges [PDF]
, 2006 The discovery that a plasmid-partitioning ATPase forms astral cytoskeletal structures both unveils a new family of cytoskeletal proteins and suggests that cytoskeletal involvement is a universal feature of DNA ...
Gitai, Zemer
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