Results 41 to 50 of about 197,265 (291)
Inositol 1,4,5-trisphosphate receptor associated with focal contact cytoskeletal proteins [PDF]
The linkage between inositol 1,4,5-trisphosphate (IP3) receptors (IP3Rs) and cytoskeletal proteins is considered to be important in cell function. In the present study, the association of IP3R subtypes with cytoskeletal proteins was examined using ...
Sugiyama, Tomoyasu +5 more
core +1 more source
Connecting two arrays: The emerging role of actin-microtubule cross-linking motor proteins
The cytoskeleton of plant cells, consisting of actin filaments (AFs) and microtubules (MTs), is a central structure for various intracellular processes, such as cell division, isotropic and polar growth, vesicle transport, cell shape and morphogenesis ...
René eSchneider, Staffan ePersson
doaj +1 more source
Glioblastoma is the deadliest malignant brain tumor. Its location behind the blood–brain barrier (BBB) presents a therapeutic challenge by preventing effective delivery of most chemotherapeutics.
Brittanie R. Partridge +10 more
doaj +1 more source
Modulation of phosphorylation of neuronal cytoskeletal proteins by neuronal depolarization. [PDF]
1. The neuronal cytoskeletal protein tau and the carboxy tails of cytoskeletal proteins neurofilament-M (NF-M) and neurofilament-H (NF-H) are phosphorylated on serine residues by the cyclin-dependent kinase cdk-5. 2.
Honegger, P., Mata, M., Fink, D.J.
core +1 more source
Cytoskeletal proteins: The evolution of cell division [PDF]
The prokaryotic cell division protein FtsZ and eukaryotic tubulin have been shown to have very similar structures and are most likely homologs. The evolutionary transition from FtsZ to tubulin could provide a window into the transition from prokaryotic cells to eukaryotic cells.
Faguy, David M., Doolittle, W.Ford
openaire +2 more sources
Regulation of store-operated Ca2+ entry by Septins
The mechanism of store-operated Ca2+entry (SOCE) brings extracellular Ca2+ into cells after depletion of intracellular Ca2+ stores. Regulation of Ca2+ homeostasis by SOCE helps control various intracellular signaling functions in both non-excitable and ...
Bipan Kumar Deb, Gaiti Hasan
doaj +1 more source
Cytoskeletal Protein Variants Driving Atrial Fibrillation: Potential Mechanisms of Action
The most common clinical tachyarrhythmia, atrial fibrillation (AF), is present in 1–2% of the population. Although common risk factors, including hypertension, diabetes, and obesity, frequently underlie AF onset, it has been recognized that in 15% of the
Stan W. van Wijk +4 more
doaj +1 more source
SHIP2 interaction with the cytoskeletal protein Vinexin [PDF]
The src homology 2 (SH2) domain‐containing inositol 5‐phosphatase 2 (SHIP2) catalyses the dephosphorylation of phosphatidylinositol 3,4,5‐trisphosphate [PtdIns(3,4,5)P3] to phosphatidylinositol 3,4‐bisphosphate [PtdIns(3,4)P2]. We report the identification of the cytoskeletal protein Vinexin as a protein interacting with SHIP2.
Paternotte, Nathalie +8 more
openaire +3 more sources
Cellular levels of Grb2 and cytoskeleton stability are correlated in a neurodegenerative scenario
Alzheimer's disease (AD) manifests as neuronal loss. On the premise of Grb2 overexpression in AD mouse brain and brain tissues of AD patients, our study primarily focuses on the stability of cytoskeletal proteins in the context of degenerative AD-like ...
Piyali Majumder +4 more
doaj +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source

