Results 41 to 50 of about 1,756,170 (285)

Shigella flexneri utilize the spectrin cytoskeleton during invasion and comet tail generation

BMC Microbiology, 2012
Background The spectrin cytoskeleton is emerging as an important host cell target of enteric bacterial pathogens. Recent studies have identified a crucial role for spectrin and its associated proteins during key pathogenic processes of Listeria ...
Ruetz Tyson J, Lin Ann E, Guttman Julian A   +2 more
doaj   +1 more source

Crosstalk between Mitochondria and Cytoskeleton in Cardiac Cells

Cells, 2020
Elucidation of the mitochondrial regulatory mechanisms for the understanding of muscle bioenergetics and the role of mitochondria is a fundamental problem in cellular physiology and pathophysiology. The cytoskeleton (microtubules, intermediate filaments,
Andrey V. Kuznetsov, Sabzali Javadov, Michael Grimm, Raimund Margreiter, Michael J. Ausserlechner, Judith Hagenbuchner   +5 more
doaj   +1 more source

Novel keratins identified by quantitative proteomic analysis as the major cytoskeletal proteins of equine (Equus caballus) hoof lamellar tissue

, 2010
The dermo-epidermal interface that connects the equine distal phalanx to the cornified hoof wall withstands great biomechanical demands, but is also a region where structural failure often ensues as a result of laminitis.
R. A. Carter, Shekk, V., Galantino-Homer, H.L., M. A. de Laat, Pollitt, C.C., V. Shekk, Carter, R.A., C. C. Pollitt, de Laat, M.A., H. L. Galantino-Homer   +9 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Quantifying cytoskeletal protein interactions with far Western blotting

Frontiers in Molecular Biosciences
The study of cytoskeletal proteins has been limited by some of their intrinsic properties, such as fixed intracellular localization and insolubility, which limit the implementation of many protein–protein interaction assays.
Marcelo M. Melo, Elizabeth S. Phillippi, Mark L. Schultz, Susan Q. Shen, Hatem El-Shanti   +4 more
doaj   +1 more source

Neural stem cells over-expressing brain-derived neurotrophic factor promote neuronal survival and cytoskeletal protein expression in traumatic brain injury sites

Neural Regeneration Research, 2017
Cytoskeletal proteins are involved in neuronal survival. Brain-derived neurotrophic factor can increase expression of cytoskeletal proteins during regeneration after axonal injury.
Tao Chen, Yan Yu, Liu-jiu Tang, Li Kong, Cheng-hong Zhang, Hai-ying Chu, Liang-wei Yin, Hai-ying Ma   +7 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

IQGAP1 interacts with components of the slit diaphragm complex in podocytes and is involved in podocyte migration and permeability in vitro.

PLoS ONE, 2012
IQGAP1 is a scaffold protein that interacts with proteins of the cytoskeleton and the intercellular adhesion complex. In podocytes, IQGAP1 is associated with nephrin in the glomerular slit diaphragm (SD) complex, but its role remains ill-defined. In this
Claire Rigothier, Patrick Auguste, Gavin I Welsh, Sébastien Lepreux, Colette Deminière, Peter W Mathieson, Moin A Saleem, Jean Ripoche, Christian Combe   +8 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Sex hormones regulate cytoskeletal proteins involved in brain plasticity

Frontiers in Psychiatry, 2015
In the brain of female mammals, including humans, a number of physiological and behavioral changes occur as a result of sex hormone exposure. Estradiol and progesterone regulate several brain functions including learning and memory.
VALERIA eHANSBERG-PASTOR, ALIESHA eGONZÁLEZ-ARENAS, ANA GABRIELA PIÑA-MEDINA, IGNACIO eCAMACHO-ARROYO, IGNACIO eCAMACHO-ARROYO   +4 more
doaj   +1 more source