Results 11 to 20 of about 197,265 (291)
Intrinsic Structural Disorder in Cytoskeletal Proteins [PDF]
Cytoskeleton, 2013 Cytoskeleton, the internal scaffold of the cell, displays an exceptional combination of stability and dynamics. It is composed of three major filamentous networks, microfilaments (actin filaments), intermediate filaments (neurofilaments), and microtubules.
Guha Roy, Mainak +4 more
openaire +6 more sources
Targeting cytoskeletal phosphorylation in cancer [PDF]
Exploration of Targeted Anti-tumor Therapy, 2021 Phosphorylation of cytoskeletal proteins regulates the dynamics of polymerization, stability, and disassembly of the different types of cytoskeletal polymers. These control the ability of cells to migrate and divide.
Clara Llorente-González +2 more
doaj +3 more sources
Nucleocytoplasmic Shuttling of Cytoskeletal Proteins: Molecular Mechanism and Biological Significance [PDF]
International Journal of Cell Biology, 2012 Various nuclear functional complexes contain cytoskeletal proteins as regulatory subunits; for example, nuclear actin participates in transcriptional complexes, and actin-related proteins are integral to chromatin remodeling complexes.
Masahiro Kumeta +3 more
doaj +2 more sources
Interactions between β-arrestin proteins and the cytoskeletal system, and their relevance to neurodegenerative disorders [PDF]
Frontiers in Endocrinology, 2023 β-arrestins, which have multiple cellular functions, were initially described as proteins that desensitize rhodopsin and other G protein-coupled receptors.
Tibor Szénási +4 more
doaj +2 more sources
Transcriptomic Characteristics Associated With Aging in the Thyroid Gland
Frontiers in Nutrition, 2022 The aging thyroid is associated with a plethora of morphological and functional changes. Limited studies have addressed the gene expression signature in the aging thyroid, except for sporadic reports using data from postmortem samples in the Genotype ...
Chien-Liang Liu +5 more
doaj +1 more source
Shaping neurodevelopment: distinct contributions of cytoskeletal proteins. [PDF]
Curr Opin Neurobiol, 2018 Development of a neuron critically depends on the organization of its cytoskeleton. Cytoskeletal components, such as tubulins and actins, have the remarkable ability to organize themselves into filaments and networks to support specialized and ...
Tang NH, Jin Y.
europepmc +3 more sources
S‐nitrosylation of cytoskeletal proteins [PDF]
Cytoskeleton, 2019 AbstractNitric oxide has pronounced effects on cellular functions normally associated with the cytoskeleton, including cell motility, shape, contraction, and mitosis. Protein S‐nitrosylation, the covalent addition of a NO group to a cysteine sulfur, is a signaling pathway for nitric oxide that acts in parallel to cyclic guanosine monophosphate (cGMP ...
Allison L. Horenberg +4 more
openaire +2 more sources
Cell Reports, 2023 Summary: Appropriate cytoskeletal organization is essential for vascular smooth muscle cell (VSMC) conditions such as hypertension. This study identifies FXR1 as a key protein linking cytoskeletal dynamics with mRNA stability.
Amanda St. Paul +8 more
doaj +1 more source
Cytoskeletal Expression and Remodeling in Pluripotent Stem Cells. [PDF]
PLoS ONE, 2016 Many emerging cell-based therapies are based on pluripotent stem cells, though complete understanding of the properties of these cells is lacking. In these cells, much is still unknown about the cytoskeletal network, which governs the mechanoresponse ...
Liana C Boraas +3 more
doaj +1 more source
Specific integrin alpha and beta chain phosphorylations regulate LFA-1 activation through affinity-dependent and -independent mechanisms [PDF]
, 2005 Integrins are adhesion receptors that are crucial to the functions of multicellular organisms. Integrin-mediated adhesion is a complex process that involves both affinity regulation and cytoskeletal coupling, but the molecular mechanisms behind this ...
Susanna C. Fagerholm +11 more
core +1 more source