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A Large and Intact Viral Particle Penetrates the Endoplasmic Reticulum Membrane to Reach the Cytosol
Non-enveloped viruses penetrate host membranes to infect cells. A cell-based assay was used to probe the endoplasmic reticulum (ER)-to-cytosol membrane transport of the non-enveloped SV40.
Takamasa Inoue, Billy Tsai
exaly +3 more sources
Co-cultured methanogen improved the metabolism in the hydrogenosome of anaerobic fungus as revealed by gas chromatography-mass spectrometry analysis [PDF]
Objective The purpose of this study was to reveal the metabolic shift in the fungus co-cultured with the methanogen (Methanobrevibacter thaueri). Methods Gas chromatography-mass spectrometry was used to investigate the metabolites in anaerobic fungal ...
Yuqi Li+4 more
doaj +1 more source
Voltage-dependent anion-selective channels (VDAC) maintain the bidirectional flow of small metabolites across the mitochondrial outer membrane and participate in the regulation of multiple cellular processes.
Sabbir R. Shuvo+4 more
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Direct injury of mitochondrial respiratory chain (RC) complex I by Ndufs4 subunit mutations results in complex I deficiency (CID) and a progressive encephalomyopathy, known as Leigh syndrome.
Gunter van der Walt+3 more
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Size of the protein-protein energy funnel in crowded environment
Association of proteins to a significant extent is determined by their geometric complementarity. Large-scale recognition factors, which directly relate to the funnel-like intermolecular energy landscape, provide important insights into the basic rules ...
Nathan W. Jenkins+3 more
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Simple and Efficient Protocol for Subcellular Fractionation of Normal and Apoptotic Cells
Subcellular fractionation approaches remain an indispensable tool among a large number of biochemical methods to facilitate the study of specific intracellular events and characterization of protein functions.
Viacheslav V. Senichkin+3 more
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Ser-Thr phosphatases in the rat brain that dephosphorylate phospho-Ser(1291)-GluN2A subunit of glutamate receptor [PDF]
N-methyl-D-aspartate receptors (NMDARs), are one of the major ionotropic glutamate receptors found in excitatory synapses which play a key role in glutamatergic synaptic transmission.
R. R. Prabhu
doaj +1 more source
Long noncoding RNAs (lncRNAs) play crucial roles in cardiovascular diseases. To date, only limited studies have reported the role of mitochondria-derived lncRNAs in heart failure (HF).
Xudong Zhang+12 more
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A colloidal particle placed inside the cell cytoplasm is enmeshed within a network of cytoskeletal fibres immersed in the cytosolic fluid. The translational mode is believed to yield different rheological parameters than the rotational mode, given that ...
Srestha Roy+6 more
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IntroductionDespite the critical role of programmed cell death (PCD) in plant development and defense responses, its regulation is not fully understood.
Johanna Schwarze+4 more
doaj +1 more source