Results 1 to 10 of about 322,139 (355)

A Large and Intact Viral Particle Penetrates the Endoplasmic Reticulum Membrane to Reach the Cytosol

open access: yesPLoS Pathogens, 2011
Non-enveloped viruses penetrate host membranes to infect cells. A cell-based assay was used to probe the endoplasmic reticulum (ER)-to-cytosol membrane transport of the non-enveloped SV40.
Takamasa Inoue, Billy Tsai
exaly   +3 more sources

Co-cultured methanogen improved the metabolism in the hydrogenosome of anaerobic fungus as revealed by gas chromatography-mass spectrometry analysis [PDF]

open access: yesAsian-Australasian Journal of Animal Sciences, 2020
Objective The purpose of this study was to reveal the metabolic shift in the fungus co-cultured with the methanogen (Methanobrevibacter thaueri). Methods Gas chromatography-mass spectrometry was used to investigate the metabolites in anaerobic fungal ...
Yuqi Li   +4 more
doaj   +1 more source

Proteomic Shifts Reflecting Oxidative Stress and Reduced Capacity for Protein Synthesis, and Alterations to Mitochondrial Membranes in Neurospora crassa Lacking VDAC

open access: yesMicroorganisms, 2022
Voltage-dependent anion-selective channels (VDAC) maintain the bidirectional flow of small metabolites across the mitochondrial outer membrane and participate in the regulation of multiple cellular processes.
Sabbir R. Shuvo   +4 more
doaj   +1 more source

Sub-Cellular Metabolomics Contributes Mitochondria-Specific Metabolic Insights to a Mouse Model of Leigh Syndrome

open access: yesMetabolites, 2021
Direct injury of mitochondrial respiratory chain (RC) complex I by Ndufs4 subunit mutations results in complex I deficiency (CID) and a progressive encephalomyopathy, known as Leigh syndrome.
Gunter van der Walt   +3 more
doaj   +1 more source

Size of the protein-protein energy funnel in crowded environment

open access: yesFrontiers in Molecular Biosciences, 2022
Association of proteins to a significant extent is determined by their geometric complementarity. Large-scale recognition factors, which directly relate to the funnel-like intermolecular energy landscape, provide important insights into the basic rules ...
Nathan W. Jenkins   +3 more
doaj   +1 more source

Simple and Efficient Protocol for Subcellular Fractionation of Normal and Apoptotic Cells

open access: yesCells, 2021
Subcellular fractionation approaches remain an indispensable tool among a large number of biochemical methods to facilitate the study of specific intracellular events and characterization of protein functions.
Viacheslav V. Senichkin   +3 more
doaj   +1 more source

Ser-Thr phosphatases in the rat brain that dephosphorylate phospho-Ser(1291)-GluN2A subunit of glutamate receptor [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2023
N-methyl-D-aspartate receptors (NMDARs), are one of the major ionotropic glutamate receptors found in excitatory synapses which play a key role in glutamatergic synaptic transmission.
R. R. Prabhu
doaj   +1 more source

Overexpression of cytosolic long noncoding RNA cytb protects against pressure-overload-induced heart failure via sponging microRNA-103-3p

open access: yesMolecular Therapy: Nucleic Acids, 2022
Long noncoding RNAs (lncRNAs) play crucial roles in cardiovascular diseases. To date, only limited studies have reported the role of mitochondria-derived lncRNAs in heart failure (HF).
Xudong Zhang   +12 more
doaj   +1 more source

Comparison of translational and rotational modes towards passive rheology of the cytoplasm of MCF-7 cells using optical tweezers

open access: yesFrontiers in Physics, 2023
A colloidal particle placed inside the cell cytoplasm is enmeshed within a network of cytoskeletal fibres immersed in the cytosolic fluid. The translational mode is believed to yield different rheological parameters than the rotational mode, given that ...
Srestha Roy   +6 more
doaj   +1 more source

The boundary of life and death: changes in mitochondrial and cytosolic proteomes associated with programmed cell death of Arabidopsis thaliana suspension culture cells

open access: yesFrontiers in Plant Science, 2023
IntroductionDespite the critical role of programmed cell death (PCD) in plant development and defense responses, its regulation is not fully understood.
Johanna Schwarze   +4 more
doaj   +1 more source

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