Results 1 to 10 of about 453,295 (313)

Proteomic Shifts Reflecting Oxidative Stress and Reduced Capacity for Protein Synthesis, and Alterations to Mitochondrial Membranes in Neurospora crassa Lacking VDAC

open access: yesMicroorganisms, 2022
Voltage-dependent anion-selective channels (VDAC) maintain the bidirectional flow of small metabolites across the mitochondrial outer membrane and participate in the regulation of multiple cellular processes.
Sabbir R. Shuvo   +4 more
doaj   +1 more source

Sub-Cellular Metabolomics Contributes Mitochondria-Specific Metabolic Insights to a Mouse Model of Leigh Syndrome

open access: yesMetabolites, 2021
Direct injury of mitochondrial respiratory chain (RC) complex I by Ndufs4 subunit mutations results in complex I deficiency (CID) and a progressive encephalomyopathy, known as Leigh syndrome.
Gunter van der Walt   +3 more
doaj   +1 more source

Overexpression of cytosolic long noncoding RNA cytb protects against pressure-overload-induced heart failure via sponging microRNA-103-3p

open access: yesMolecular Therapy: Nucleic Acids, 2022
Long noncoding RNAs (lncRNAs) play crucial roles in cardiovascular diseases. To date, only limited studies have reported the role of mitochondria-derived lncRNAs in heart failure (HF).
Xudong Zhang   +12 more
doaj   +1 more source

Comparison of translational and rotational modes towards passive rheology of the cytoplasm of MCF-7 cells using optical tweezers

open access: yesFrontiers in Physics, 2023
A colloidal particle placed inside the cell cytoplasm is enmeshed within a network of cytoskeletal fibres immersed in the cytosolic fluid. The translational mode is believed to yield different rheological parameters than the rotational mode, given that ...
Srestha Roy   +6 more
doaj   +1 more source

Co-cultured methanogen improved the metabolism in the hydrogenosome of anaerobic fungus as revealed by gas chromatography-mass spectrometry analysis [PDF]

open access: yesAsian-Australasian Journal of Animal Sciences, 2020
Objective The purpose of this study was to reveal the metabolic shift in the fungus co-cultured with the methanogen (Methanobrevibacter thaueri). Methods Gas chromatography-mass spectrometry was used to investigate the metabolites in anaerobic fungal ...
Yuqi Li   +4 more
doaj   +1 more source

Ser-Thr phosphatases in the rat brain that dephosphorylate phospho-Ser(1291)-GluN2A subunit of glutamate receptor [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2023
N-methyl-D-aspartate receptors (NMDARs), are one of the major ionotropic glutamate receptors found in excitatory synapses which play a key role in glutamatergic synaptic transmission.
R. R. Prabhu
doaj   +1 more source

Size of the protein-protein energy funnel in crowded environment

open access: yesFrontiers in Molecular Biosciences, 2022
Association of proteins to a significant extent is determined by their geometric complementarity. Large-scale recognition factors, which directly relate to the funnel-like intermolecular energy landscape, provide important insights into the basic rules ...
Nathan W. Jenkins   +3 more
doaj   +1 more source

Simple and Efficient Protocol for Subcellular Fractionation of Normal and Apoptotic Cells

open access: yesCells, 2021
Subcellular fractionation approaches remain an indispensable tool among a large number of biochemical methods to facilitate the study of specific intracellular events and characterization of protein functions.
Viacheslav V. Senichkin   +3 more
doaj   +1 more source

The boundary of life and death: changes in mitochondrial and cytosolic proteomes associated with programmed cell death of Arabidopsis thaliana suspension culture cells

open access: yesFrontiers in Plant Science, 2023
IntroductionDespite the critical role of programmed cell death (PCD) in plant development and defense responses, its regulation is not fully understood.
Johanna Schwarze   +4 more
doaj   +1 more source

Trehalose as a Stabilizer of the Lipid Composition of Membranes and the Composition of the Cytosol of Frozen/Thawed Rooster Spermatozoa

open access: yesAgriculture, 2023
Low-temperature semen storage technologies are already being used in poultry conservation programs, but the quality of reproductive material stored in cryobanks varies greatly and cannot always be successfully used for practical purposes.
Olga Stanishevskaya   +6 more
doaj   +1 more source

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