This study uncovers a novel mechanism in which p300‑catalyzed lactylation of HMGB1 triggers nuclear export of the HMGB1‐TIAR complex, driving TIAR‐dependent SGs formation in the cytoplasm. Mass spectrometry and mutagenesis reveals that K177 lactylation is essential for this export and subsequent SGs formation.
Chengyu Li+8 more
wiley +1 more source
Transcriptomics and trans-organellar complementation reveal limited signaling of 12-cis-oxo-phytodienoic acid during early wound response in Arabidopsis. [PDF]
Mekkaoui K+5 more
europepmc +1 more source
The Binding of Tritiated Aldosterone in the Rat Liver Cytosol1
Dominique Duval, John W. Funder
openalex +1 more source
M. tuberculosis and M. leprae Translocate from the Phagolysosome to the Cytosol in Myeloid Cells
N. Wel+7 more
semanticscholar +1 more source
Targeting Kupffer cells (KC) with a single intravenous infusion of the oncolytic virus VSV‐M51R rather than VSV‐WT induces effective tumor regression in various types of liver metastatic cancers in mice. VSV‐M51R promotes KC proliferation and enhances their antigen cross‐presentation capacity without compromising viability, leading to the induction of ...
Chen Chen+8 more
wiley +1 more source
Cytoplasmic physicochemical factors drive malignant transformation by adapting bioenergetic settings. [PDF]
Shaiken TE.
europepmc +1 more source
Cell‐free synthesis of rat liver δ‐aminolevulinate synthase and possible occurrence of processing of the enzyme protein in the course of its translocation from the cytosol into the mitochondrial matrix [PDF]
Kohei Yamauchi+2 more
openalex +1 more source
This review first summarizes the complex pathogenesis of atherosclerosis and outlines the limitations of conventional therapies. It then explores innovative nanoparticle drug delivery system (NDDS) developments, detailing their precision targeting strategies, responsiveness to plaque‐specific stimuli, modulation of key pathological processes, and ...
Yunqi Zhang+13 more
wiley +1 more source
Induction of cyclic AMP‐dependent phosphorylation in cytosol of differentiating mouse erythroleukemia cell line 179 [PDF]
Carol A. Emler+2 more
openalex +1 more source