Results 221 to 230 of about 256,621 (293)

Mitochondrial DNA in Exercise-Mediated Innate Immune Responses. [PDF]

open access: yesInt J Mol Sci
Wen X   +5 more
europepmc   +1 more source

Structure and mechanism of human vesicular polyamine transporter. [PDF]

open access: yesNat Commun
Guo Y   +8 more
europepmc   +1 more source

Intracellular Delivery of Native Proteins by BioReversible Arginine Modification (BioRAM) on Amino Groups

open access: yesAngewandte Chemie International Edition, EarlyView.
Bioreversible Arginine Modification of amine‐containing protein residues (termed BioRAM) allows the serum‐compatible, readily accessible, and efficient delivery of native proteins into live cells. Combined with cell‐penetrating peptide (CPP) additives, BioRAM results in intracellular RNase A activity at nanomolar concentrations, thus enabling the ...
Jonathan Franke   +3 more
wiley   +1 more source

Unsaturated Phosphine Oxides for Modular Antibody Rebridging and Single Reagent Peptide‐Cyclisation‐Bioconjugation

open access: yesAngewandte Chemie International Edition, Accepted Article.
Achieving modular, selective and homogeneous protein modifications is of utmost importance for the design of next generation biopharmaceuticals; especially in the context of antibody‐drug conjugates (ADCs). Here, we introduce unsaturated phosphine oxides as versatile triple‐reactive reagents, allowing orthogonal chemoselective bioconjugation schemes ...
Christian E. Stieger   +5 more
wiley   +1 more source

Arabidopsis SGS3 is recruited to chromatin by CHR11 to select RNA that initiate siRNA production. [PDF]

open access: yesNat Commun
Elmayan T   +7 more
europepmc   +1 more source

Cytosolic Delivery of Functional Ubiquitin. [PDF]

open access: yesJ Pept Sci
Giancola JB   +4 more
europepmc   +1 more source

Embracing Complexity: Peptides as Tuneable Scaffolds in the Construction of Discrete Supramolecular Systems

open access: yesAngewandte Chemie International Edition, Accepted Article.
Supramolecular chemistry has advanced rapidly, with scientists using fundamental understanding to generate function from simple building blocks. However, synthetic systems are still in their infancy when compared to biology. The increasing use of peptides in supramolecular structures provides a clear roadmap to more complex function; introducing chiral,
Ben E. Barber   +3 more
wiley   +1 more source

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