Results 221 to 230 of about 336,446 (348)

Interplay of Mg2+, ADP, and ATP in the cytosol and mitochondria: Unravelling the role of Mg2+ in cell respiration

Proceedings of the National Academy of Sciences of the United States of America, 2014
E. Gout, F. Rébeillé, R. Douce, R. Bligny   +3 more
semanticscholar   +1 more source

Leucine‐Dependent SLC7A5–PGAM5 Interaction Promotes Advanced Atherosclerosis Through Hindering Mitochondrial Function of Macrophages

Advanced Science, EarlyView.
Higher plasma leucine is associated with increased risk of new‐onset myocardial infarction. Leucine deprivation alleviates advanced atherosclerosis in mice. Tumor‐induced leucine deprivation reprograms macrophage metabolism and increases CD5Lhi macrophages in mouse plaques. Mechanistically, leucine deficiency reduced SLC7A5‐PGAM5 binding in macrophages,
Shan Zhong, Xueyu Wang, Qingsong Li, Siqi Wang, Bin Sun, Wenjun Ni, Gengyu Zhou, Fan Wang, Xianwei Xie, Cheng Jin, Gang Xu, Peng Zhao, Xiang Peng, Feiyuan Han, Xiangwen Xi, Yidan Wang, Juan Xu, Yue Wang, Xia Gu, Shuo Li, Jian Zhang, Shuijie Li, Jinwei Tian   +22 more
wiley   +1 more source

Uncovering cargo clients and accessory factors of AP-1 and AP-4 through vesicle proteomics. [PDF]

Proc Natl Acad Sci U S A
Peng Z, Fan J, Liu Y, Jia Q, An J, Wang J, Huang Y, Yao ZP, Guo Y.   +8 more
europepmc   +1 more source

The nuclear export signal-dependent localization of oligonucleopeptides enhances the inhibition of the protein expression from a gene transcribed in cytosol [PDF]

, 1999
Laurence Meunier, Roger Mayer, Michel Monsigny, A. C. Roche   +3 more
openalex   +1 more source

SIRT5–RAC2 Axis Drives Monocyte‐to‐Macrophage Differentiation to Promote Inflammatory Injury in Premature Ovarian Insufficiency

Advanced Science, EarlyView.
SIRT5 desuccinylates and stabilizes RAC2, activating CSF1R‐dependent signaling to drive monocyte differentiation into M0 macrophages and their polarization toward pro‐inflammatory M1 phenotypes in CTX‐induced premature ovarian insufficiency. Inhibiting the SIRT5‐RAC2 axis attenuates inflammation, reduces granulosa cell apoptosis, and preserves ...
Wenjing TanTai, Yaqi Li, Shengnan Liu, Minjuan Wu, Zhixiao Liu, Junfeng Jiang, Jingjing Chen, Xiaoding Xu, Li Li, Chaoqun Li, Fang Zhao, Ye Liu, Haitao Ni, Tengfei Zhang, Mingjuan Xu, Chaofeng Han   +15 more
wiley   +1 more source

Non-genetic inactivation of caspase-3 and P53 increases cancer cell fitness by PDIA4 redistribution. [PDF]

Oncogene
Twito G, Abu Abayed FA, Gilad A, Biadsy S, Gavriel N, Sheikh Suliman S, Mizrahi Y, Megged H, Tenenboim M, Abu-Freha N, Igbaria A.   +10 more
europepmc   +1 more source

Transcription of genomic bovine and Xenopus laevis DNA species by RNA polymerase III in HeLa-cell cytosol extracts [PDF]

, 1986
J. Fürth, Chun-Yeh Su
openalex   +1 more source

Biomimetic Iridium‐Based Photothermal Nanozyme to Trigger Ferroptosis and Pyroptosis and Activate the cGAS‐STING Pathway for Improved Tumor Immunotherapy

Advanced Science, EarlyView.
This study develops an iridium‐based nanozyme (IIN@M) with superior enzyme‐like activity and photothermal performance. It disrupts intracellular redox balance by generating reactive oxygen species and depleting glutathione, which synergistically induces ferroptosis, pyroptosis, and immunogenic cell death.
Lijun Ding, Zhongxiong Fan, Guoyu Xia, Fukai Zhu, Nan Yang, Shujie Yu, Longlong Yuan, Jinyao Li   +7 more
wiley   +1 more source

ARTS Confers Chemoresistance of Breast Cancer by Inducing Apoptosis-Dependent Autophagy via Livin-MDM2-p53 Pathway. [PDF]

Research (Wash D C)
Wang H, Guo Q, Shen Y, Ding K, Chen Y, Wang X, Huang X, Wu Z.   +7 more
europepmc   +1 more source

Signaling in the plant cytosol: cysteine or sulfide?

Amino Acids, 2014
C. Gotor, Ana M. Laureano-Marín, I. Moreno, Á. Aroca, I. García, L. Romero   +5 more
semanticscholar   +1 more source