Results 251 to 260 of about 322,139 (355)

Biochemistry of Heat Shock Proteins From Human Intracellular Protozoan Parasites as Diagnostic and Therapeutic Biomarkers. [PDF]

Biochemistry
Chakafana G, Zininga T.
europepmc   +1 more source

CALMODULIN STIMULATES DEPHOSPHORYLATION OF A 90 kDa PROTEIN IN THE HUMAN INSULINOMA CYTOSOL

, 1983
Akira Matsutani, Kohei Kaku, Toshio Kaneko   +2 more
openalex   +2 more sources

In Vitro Monitoring of Babesia microti Infection Dynamics in Whole Blood Microenvironments

Advanced Science, EarlyView.
Here, an open microfluidic platform termed “µ‐Blood” is reported for real‐time, continuous monitoring of Babesia microti infection dynamics in vitro. µ‐Blood allows direct interrogation of whole blood with preserved integrity of the original whole blood microenvironment through an extended period (e.g., 72 h with mouse red blood cells) ex vivo. µ‐Blood
Chao Li, Emily G. Bache, Amy L. Apgar, Danielle M. Tufts, Tagbo H. R. Niepa   +4 more
wiley   +1 more source

Hsa_circ_0026782 Acts as a “Molecular Break” of CREB1‐Mediated Transcription by Promoting Its Phosphorylation at Ser142 That Prevents Keloid Progression

Advanced Science, EarlyView.
Model for the role of hsa_circ_0026782/p‐CREB1 (Ser142) played in keloid. Hsa_circ_0026782 is derived from back‐splicing of ITGA7 exon 4. When hsa_circ_0026782 binds to CREB1, the exposure of the bZIP domain and dimerization of CREB1 are promoted (upper left).
Xin‐Cao Zhong, Chun‐Ye Chen, Zi‐Xuan Feng, Yong Wang, Tao Zhang, Ze‐Ming Zhuang, Zhang‐Rui Wu, Yong‐Zhong Du, Jun Chen, Xiao‐Ying Lin, Wei‐Qiang Tan   +10 more
wiley   +1 more source

Hastened Fusion-Dependent Endosomal Escape Improves Activity of Delivered Enzyme Cargo. [PDF]

ACS Cent Sci
Vázquez-Maldonado AL, Chen T, Rodriguez D, Zoltek M, Schepartz A.   +4 more
europepmc   +1 more source

Enhancing the β‐Oxidation‐Like Pathway for the Optimal Production of the Immunosuppressant Mycophenolic Acid

Advanced Science, EarlyView.
The most elaborate known example of β‐oxidation‐like pathway recruitment in fungi is reported, involving a 10‐step oxidative chain‐shortening cascade catalyzed by five dedicated enzymes to generate the pharmacophore of mycophenolic acid (MPA)—a novel clinical immunosuppressant. Our findings illustrate how nature repurposes catabolic enzymes for complex
Baoqiang Fan, Yinuo Liu, Lu‐ping Chi, Chaofan Yang, Shengying Li, Wei Zhang   +5 more
wiley   +1 more source

Breaking the cellular delivery bottleneck: recent developments in direct cytosolic delivery of biologics.

RSC Pharm
Nagaraj H, Lehot V, Nasim N, Cicek YA, Goswami R, Jeon T, Rotello VM.   +6 more
europepmc   +1 more source

Cytosolic and endoplasmic reticulum chaperones inhibit wt-p53 to increase cancer cells' survival by refluxing ER-proteins to the cytosol. [PDF]

Elife
Dabsan S, Zur G, Abu-Freha N, Sofer S, Grossman-Haham I, Gilad A, Igbaria A.   +6 more
europepmc   +1 more source

Structure and function of the Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Species difference in molecular properties of the receptors from mouse and rat hepatic cytosols.

, 1986
Michael S. Denison, Lynn M. Vella, Allan B. Okey   +2 more
openalex   +1 more source

Impact of reconstituted cytosol on protein stability

Proceedings of the National Academy of Sciences of the United States of America, 2013
Mohona Sarkar, Austin E. Smith, G. Pielak   +2 more
semanticscholar   +1 more source