Results 51 to 60 of about 1,890 (188)

Hemoadsorption by CytoSorb in septic patients: a case series [PDF]

open access: yesCritical Care, 2017
Septic shock, defined as life-threatening organ dysfunction caused by a dysregulated host response to infection, is a highly lethal condition that causes substantial morbidity and mortality among critically ill patients. One of the hallmarks of sepsis is the excessive release of cytokines and other inflammatory mediators causing refractory hypotension,
Klaus Kogelmann   +3 more
openaire   +3 more sources

Immunomodulation by Hemoadsorption—Changes in Hepatic Biotransformation Capacity in Sepsis and Septic Shock: A Prospective Study

open access: yesBiomedicines, 2022
Background: Sepsis is often associated with liver dysfunction, which is an indicator of poor outcomes. Specific diagnostic tools that detect hepatic dysfunction in its early stages are scarce.
Janina Praxenthaler   +6 more
doaj   +1 more source

Hemoadsorption eliminates remdesivir from the circulation: Implications for the treatment of COVID‐19

open access: yesPharmacology Research & Perspectives, 2021
Both antiviral treatment with remdesivir and hemoadsorption using a CytoSorb® adsorption device are applied in the treatment of severe COVID‐19. The CytoSorb® adsorber consists of porous polymer beads that adsorb a broad range of molecules, including ...
Paul Biever   +7 more
doaj   +1 more source

CytoSorb-friend or foe!!

open access: yesIndian Journal of Critical Care Medicine, 2015
Sir, We read the case report “use of a novel hemadsorption device for cytokine removal as adjuvant therapy in a patient with septic shock with multi-organ dysfunction: A case study” by Basu et al.[1] with great interest. We would like to share our experiences with a similar patient in our Intensive Care Unit and discuss some of the intriguing ...
Pattnaik, Saroj Kumar   +1 more
openaire   +3 more sources

CytoSorb hemoperfusion markedly attenuates circulating cytokine concentrations during systemic inflammation in humans in vivo

open access: yesCritical Care, 2023
Background The CytoSorb hemoadsorption device has been demonstrated to be capable of clearing inflammatory cytokines, but has not yet been shown to attenuate plasma cytokine concentrations.
Aron Jansen   +4 more
doaj   +1 more source

CytoSorb® usage in a dual antiplatelet agent treated patient during CABG and broken guidewire retrieval from right coronary artery ostium [PDF]

open access: yesInternational Journal of Medical Device and Adjuvant Treatments, 2022
Objective: We report a case of a patient undergoing Open Coronary Artery Bypass Graft Surgery (CABG) with CytoSorb® under dual antiplatelet therapy (DAPT) with a broken guidewire in RCA ostium.
N. Kumar, V. Keshri, R. Bhuyan
doaj   +1 more source

Opportunities, controversies, and challenges of extracorporeal hemoadsorption with CytoSorb during ECMO [PDF]

open access: yesArtificial Organs, 2021
AbstractExtracorporeal membrane oxygenation (ECMO) is frequently used in many centers around the globe for various indications. However, prognosis is often poor even with all supportive therapies, and in many cases, clinical deterioration is associated with inflammation.
Napp, L. Christian   +4 more
openaire   +3 more sources

Haemoadsorption reduces the inflammatory response and improves blood flow during ex vivo renal perfusion in an experimental model

open access: yesJournal of Translational Medicine, 2017
Background Ex-vivo normothermic perfusion strategies are a promising new instrument in organ transplantation. The perfusion conditions are designed to be protective however the artificial environment can induce a local inflammatory response.
Sarah A. Hosgood   +4 more
doaj   +1 more source

Supplementary Material for: Extracorporeal blood purification with CytoSorb in 359 critically ill patients

open access: yes, 2023
Introduction. Critically ill patients with inflammatory dysregulation and organ disfunction may benefit from blood purification, although the use of this technique has not been described in large case series.
Belletti A. (16875384)   +7 more
core   +1 more source

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