Results 41 to 50 of about 1,890 (188)

Severe Clozapine Poisoning Treated by Extracorporeal Blood Purification Therapy

Case Reports in Nephrology and Dialysis, 2023
Clozapine is a frequently used antipsychotic that, in case of overdose, can cause severe adverse side effects, such as hematological, cardiovascular, and neurological complications.
Andreas Hartjes, Matthaeus Machnik, Christa Kubasta, Karl Schrattbauer   +3 more
doaj   +1 more source

Excessive Apixaban Concentrations in a Bleeding Patient Treated With Pharmacological Reversal and Extracorporal Removal-A Case Report. [PDF]

Pharmacol Res Perspect
Excessive apixaban concentrations in a bleeding patient leading to impaired coagulation and treatment with pharmacological reversal and extracorporal removal. ABSTRACT In trauma, even therapeutic apixaban levels can significantly exacerbate bleeding.
Kraus RF, Rosenberger J, Dejaco A, Paal M, Hart C, Burkhardt R, Kees MG.   +6 more
europepmc   +2 more sources

Hemoadsorption in the critically ill—Final results of the International CytoSorb Registry [PDF]

PLOS ONE, 2022
The aim of the current paper is to summarize the results of the International CytoSorb Registry. Data were collected on patients of the intensive care unit. The primary endpoint was actual in-hospital mortality compared to the mortality predicted by APACHE II score.
Fatime Hawchar, Dana Tomescu, Karl Träger, Dominik Joskowiak, Klaus Kogelmann, Jens Soukup, Singrun Friesecke, David Jacob, Jan Gummert, Andreas Faltlhauser, Filippo Aucella, Martijn van Tellingen, Manu L. N. G. Malbrain, Ralph Bogdanski, Günter Weiss, Andreas Herbrich, Stefan Utzolino, Axel Nierhaus, Andreas Baumann, Andreas Hartjes, Dietrich Henzler, Evgeny Grigoryev, Harald Fritz, Friedhelm Bach, Stefan Schröder, Andreas Weyland, Udo Gottschaldt, Matthias Menzel, Olivier Zachariae, Radovan Novak, Jernej Berden, Hendrik Haake, Michael Quintel, Stephan Kloesel, Andreas Kortgen, Stephanie Stecher, Patricia Torti, Frieder Nestler, Markus Nitsch, Detlef Olboeter, Philip Muck, Michael Findeisen, Diane Bitzinger, Jens Kraßler, Martin Benad, Martin Schott, Ulrike Schumacher, Zsolt Molnar, Frank Martin Brunkhorst   +48 more
openaire   +6 more sources

Cytosorb® haemoadsorption: a potential game changer for patients needing myocardial surgical revascularisation [PDF]

, 2021
Cytosorb, an extracorporeal blood purification system, utilises the principles of haemoadsorption to remove low molecular weight substances from the blood, including multiple cytokines such as interleukin (IL)-1b, IL-6, IL-8, and tumour necrosis factor-α,
Marczin, Nandor, Stock, Ulrich A, Umakumar, Kabeer, Ng Yin Ling, Clarissa, Raja, Shahzad G, de Waal, Eric EC, Moss, Louise, Shahzad G. Raja, Nandor Marczin, Ulrich A. Stock, Clarissa Ng Yin Ling, Louise Moss, Eric E.C. de Waal, Kabeer Umakumar   +13 more
core   +1 more source

CytoSorb use in critically ill patients with hyperbilirubinemia

, 2021
CytoSorb, a relatively new blood purification technique is gaining popularity with different indications in critically ill patients. Our aim is to summarize currently available data on CytoSorb use in critically ill patients with acquired hepatic injury ...
Klementina Ocskay
core   +1 more source

Strategies to mitigate inflammation in management of complex congenital heart disease complicated by “multisystem inflammatory syndrome in children”

Annals of Pediatric Cardiology, 2022
A 6-month-old boy, a case of Shone's complex, presented in decompensated state was found to have severe mitral stenosis along with multisystem inflammatory syndrome in children (MISC) warranting urgent surgical intervention.
Anil Kumar, Reena K Joshi, Neeraj Aggarwal, Mily Ray, Raja Joshi   +4 more
doaj   +1 more source

Drug Clearance and Dosing During CytoSorb Hemoadsorption: A Systematic Review. [PDF]

Crit Care Explor
OBJECTIVE: CytoSorb (CS) hemoadsorption is increasingly used in critical care and cardiac surgery to remove inflammatory mediators and select drugs. This systematic review aimed to summarize available evidence on intentional drug removal as well as unintentional drug removal during CS therapy.
Klaus T, Honoré PM, Bottari G, De Rosa S, Kindgen-Milles D, Schneider A, Marczin N, Adamson H, Scheier J, Deliargyris EN, Nolin TD.   +10 more
europepmc   +5 more sources

Artificial Liver Support with CytoSorb and MARS in Liver Failure: A Retrospective Propensity Matched Analysis

, 2023
Background: Liver failure represents a life-threatening organ dysfunction with liver transplantation as the only proven curable therapy to date. Liver assist devices have been extensively researched to either bridge such patients to transplantation or ...
Alexandra Marcu, Mihaela Roxana Olita, Corina David, Mariana Mihaila, Mihai Popescu, Dana Tomescu   +5 more
core   +1 more source

Efficacy of CytoSorb® - A Metaanalysis

, 2022
Abstract Cytokine adsorption using the CytoSorb® device has been proposed in various clinical settings including sepsis, ARDS, hyperinflammatory syndromes, cardiac surgery or recovery after cardiac arrest. The aim of this analysis is to provide evidence for the efficacy of the CytoSorb® device with regard to mortality in various settings ...
Sören Becker, Hannah Lang, Clara Vollmer Barbosa, Zhejia Tian, Anette Melk, Bernhard M.W. Schmidt   +5 more
openaire   +1 more source

Pancreatitis cytosorbents (CytoSorb) inflammatory cytokine removal

Medicine, 2019
Abstract Background: Acute pancreatitis (AP) usually has a mild course with a mortality rate below 1%. However, around 10% of patients develop severe AP (SAP) involving extra-pancreatic tissues and other organ systems. The mortality of SAP is around 42%.
Huber, Wolfgang, Algül, Hana, Lahmer, Tobias, Mayr, Ulrich, Lehmann, Miriam, Schmid, Roland M., Faltlhauser, Andreas   +6 more
openaire   +2 more sources