Critical Care, 2023 Background The CytoSorb hemoadsorption device has been demonstrated to be capable of clearing inflammatory cytokines, but has not yet been shown to attenuate plasma cytokine concentrations.
Aron Jansen +4 more
doaj +2 more sources
The Effects of CytoSorb in Critically Ill Adult Patients on Vasopressor Support: A Systematic Review and Meta-Analysis [PDF]
LifeBackground: The impact of CytoSorb hemoadsorption on hemodynamic stability, mortality, and intensive care unit length of stay in critically ill adult patients requiring vasopressor support is unclear.
Martina Giacco +4 more
doaj +2 more sources
Artificial liver support with Cytosorb and continuous veno-venous hemodiafiltration versus advanced organ support (ADVOS) for critically ill patients with hyperbilirubinemia and acute-on-chronic liver failure (ACLF) [PDF]
BMC NephrologyBackground As many as 30% of critically ill patients in intensive care units experience acute liver dysfunction with hyperbilirubinemia as a part of multiorgan failure that is associated with poor outcome.
Kristina Schönfelder +5 more
doaj +2 more sources
Early CytoSorb Hemoadsorption in a Neutropenic Acute Myeloid Leukemia Patient with Carbapenem-Resistant Pseudomonas Septic Shock and ARDS [PDF]
DiseasesNeutropenic patients with acute myeloid leukemia (AML) are at high risk for severe, multidrug-resistant infections. Sepsis due to carbapenem-resistant Pseudomonas aeruginosa (CRPA) in this population often leads to septic shock and acute respiratory ...
Wei-Hung Chang, Ting-Yu Hu, Li-Kuo Kuo
doaj +2 more sources
Hemoadsorption with CytoSorb shows a decreased observed versus expected 28-day all-cause mortality in ICU patients with septic shock: a propensity-score-weighted retrospective study [PDF]
Critical Care, 2019 Background and aims Innovative treatment modalities have not yet shown a clinical benefit in patients with septic shock. To reduce severe cytokinaemia, CytoSorb as an add-on to continuous renal replacement therapy (CRRT) showed promising results in case ...
Willem Pieter Brouwer +3 more
doaj +2 more sources
Hemoadsorption by CytoSorb in septic patients: a case series [PDF]
Critical Care, 2017 Septic shock, defined as life-threatening organ dysfunction caused by a dysregulated host response to infection, is a highly lethal condition that causes substantial morbidity and mortality among critically ill patients. One of the hallmarks of sepsis is the excessive release of cytokines and other inflammatory mediators causing refractory hypotension,
Klaus Kogelmann +3 more
openaire +5 more sources
Annals of Cardiac AnaesthesiaWe describe the case of a 72-year-old male with a history of systemic mastocytosis scheduled for on-pump aortic valve replacement for severe aortic insufficiency.
Adrien Gross +3 more
doaj +2 more sources
Hemadsorption with CytoSorb in Infants with Sepsis: Non-Systematic Review of Cases
Journal of Clinical MedicineSepsis is a severe and potentially life-threatening condition that occurs when the body’s response to an infection damages its own tissues and organs. It can lead to organ failure and death if not treated. Cytosorb is a promising medical device for hemadsorption in pediatric septic patients (under 18 years old).
Aruzhan Borankulova, Vitaliy Sazonov
openaire +3 more sources
Evaluation of Hemoadsorption Capacity of the CytoSorb Adsorber for Toxic Doses of Diclofenac and Meloxicam in Porcine Plasma. [PDF]
J Clin ApherABSTRACT The objective of this in vitro experimental was to determine the utility of hemoadsorption (HA) using the CytoSorb adsorber to remove meloxicam and diclofenac from porcine plasma. For this purpose 12 1‐L aliquots of porcine plasma, 6 units were spiked with 293 μg/mL (262–320 μg/mL) diclofenac and 6 with 42.8 μg/mL (41.4–44.7 μg/mL) meloxicam ...
Giani B +3 more
europepmc +2 more sources
Cytokine clearance with CytoSorb® during cardiac surgery: a pilot randomized controlled trial
Critical Care, 2019 Background Cardiopulmonary bypass (CPB) is often associated with degrees of complex inflammatory response mediated by various cytokines. This response can, in severe cases, lead to systemic hypotension and organ dysfunction.
Elettra C Poli +8 more
doaj +2 more sources