Results 11 to 20 of about 1,696 (185)

Efficacy of CytoSorb®: a systematic review and meta-analysis

Critical Care, 2023
Introduction Cytokine adsorption using the CytoSorb® adsorber has been proposed in various clinical settings including sepsis, ARDS, hyperinflammatory syndromes, cardiac surgery or recovery after cardiac arrest.
Sören Becker, Hannah Lang, Clara Vollmer Barbosa, Zhejia Tian, Anette Melk, Bernhard M. W. Schmidt   +5 more
doaj   +4 more sources

Use of the CytoSorb adsorber in patients with acute-on-chronic liver failure

Scientific Reports
CytoSorb is a hemoadsorptive column used to remove high concentrations of proinflammatory cytokines in septic shock. Data on CytoSorb application in acute-on-chronic liver failure (ACLF) is lacking. This retrospective observational study analyzed 21 ACLF
Patrick Haselwanter, Bernhard Scheiner, Lorenz Balcar, Georg Semmler, Marlene Riedl-Wewalka, Monika Schmid, Thomas Reiberger, Christian Zauner, Mathias Schneeweiss-Gleixner   +8 more
doaj   +4 more sources

Prevention of vasoplegia with CytoSorb in heart failure patients undergoing cardiac surgery (CytoSorb-HF trial): protocol for a randomised controlled trial [PDF]

BMJ Open, 2022
Introduction Vasoplegia is a common complication after cardiac surgery and is associated with poor prognosis. It is characterised by refractory hypotension despite normal or even increased cardiac output. The pathophysiology is complex and includes the systemic inflammatory response caused by cardiopulmonary ...
Papazisi, O., Bruggemans, E.F., Berendsen, R.R., Hugo, J.D.V., Lindeman, J.H.N., Beeres, S.L.M.A., Arbous, M.S., Hout, W.B. van den, Mertens, B.J.A., Ince, C., Klautz, R.J.M., Palmen, M.   +11 more
core   +8 more sources

Mechanistic Considerations and Pharmacokinetic Implications on Concomitant Drug Administration During CytoSorb Therapy

Critical Care Explorations, 2022
OBJECTIVE:. The CytoSorb hemoadsorption device (CytoSorbents Inc, Monmouth Junction, NJ) is increasingly used in many critical disease states. The potential impact on the pharmacokinetic (PK) of concomitantly administered drugs must be considered in ...
Joerg Scheier, MD, Peter J. Nelson, MD, FASN, Antoine Schneider, MD, PhD, Sébastien Colombier, MD, Detlef Kindgen-Milles, MD, PhD, Efthymios N. Deliargyris, MD, FACC, FESC, FSCAI, Thomas D. Nolin, PharmD, PhD   +6 more
doaj   +2 more sources

Hemadsorption with Adult CytoSorb® in a Low Weight Pediatric Case [PDF]

Case Reports in Critical Care, 2017
Cytokine adsorber (CytoSorb) has been used successfully as adjunctive treatment for adult patients with elevated cytokine levels in the setting with severe sepsis and septic shock and to reduce blood myoglobin, unconjugated bilirubin, and conjugated ...
Catalin Gabriel Cirstoveanu, Ileana Barascu, Samantha Mc Kenzie Stancu   +2 more
doaj   +4 more sources

Applications of Cytosorb in clinical practice

Journal of Pre-Clinical and Clinical Research, 2019
Introduction and objective. Cytososorb is haemadsorption device approved in the European Union in 2011 for cytokine adsorption. Recently, in 2018, new indications for the device use have been added, including bilirubin and myoglobin removal.
Paweł Kutnik, Michał Borys
openaire   +3 more sources

Does the cytokine adsorber CytoSorb® reduce vancomycin exposure in critically ill patients with sepsis or septic shock? a prospective observational study [PDF]

Annals of Intensive Care, 2022
Background Hemadsorption of cytokines is used in critically ill patients with sepsis or septic shock. Concerns have been raised that the cytokine adsorber CytoSorb® unintentionally adsorbs vancomycin.
Christina Scharf, Ferdinand Weinelt, Ines Schroeder, Michael Paal, Michael Weigand, Michael Zoller, Michael Irlbeck, Charlotte Kloft, Josef Briegel, Uwe Liebchen   +9 more
doaj   +2 more sources

Feasibility and Safety of Cytosorb Application in Patients With Acute Liver Failure. [PDF]

Liver Int
ABSTRACT Background and Aims Acute liver failure (ALF) is a rare, life‐threatening condition with high mortality and limited therapeutic options beyond liver transplantation. Cytosorb adsorber can be easily applied to continuous renal replacement therapy (CRRT) and potentially support liver ...
Haselwanter P, Fairfield S, Reinhold R, Riedl-Wewalka M, Schmid M, Balcar L, Stättermayer AF, Reiberger T, Trauner M, Zauner C, Schneeweiss-Gleixner M.   +10 more
europepmc   +5 more sources

CytoSorb removes MDMA in vitro, but is it an effective therapy in vivo?

Intensive Care Medicine Experimental, 2020
Background 3,4-Methylenedioxymethamphetamine intoxication can result in potentially lethal multi-organ failure, for which the current treatment is largely supportive.
Patrick M. Honore, Sebastien Redant, Thomas Datzmann   +2 more
doaj   +2 more sources

A single centre experience with CytoSorb® as an adjunct therapy in critically ill patients with sepsis: a case series [PDF]

International Journal of Medical Device and Adjuvant Treatments, 2023
Objective: Sepsis is an immune response to infections that are caused by bacteria, viruses, fungi, or parasites. This potentially life-threatening condition is associated with high mortality and morbidity that causes a major global health burden and ...
H. Gajera, S. Gohil, A. Chhatravala
doaj   +2 more sources