Results 31 to 40 of about 1,696 (185)

To Hemoadsorb or Not to Hemoadsorb—Do We Have the Answer Yet? An Updated Meta-Analysis on the Use of CytoSorb in Sepsis and Septic Shock

Biomedicines
Severe inflammation leading to organ dysfunction is the cornerstone of the pathophysiology of sepsis. Thus, from a theoretical point of view, rebalancing inflammation has the potential to improve patient outcomes.
Tudor Borjog, Romina-Marina Sima, Mihai Popescu   +2 more
exaly   +3 more sources

Potential Clinical Use of CytoSorb^® for Ticagrelor and Rivaroxaban Elimination Prior to Emergency Orthopedic Surgery in Trauma Patients [PDF]

Life
Background: Major orthopedic trauma in patients receiving anticoagulants such as ticagrelor or rivaroxaban poses a significant perioperative challenge, particularly in emergency contexts where bleeding risks are heightened and specific reversal agents ...
Gabriele Melegari, Fabio Gazzotti, Federica Arturi, Elisabetta Bertellini, Andrea Tognù, Domenico Pietro Santonastaso, Matteo Villani, Francesca Coppi, Fabrizio Fattorini, Fabio Catani, Alberto Barbieri   +10 more
doaj   +2 more sources

The COSMOS Registry of CytoSorb Hemoadsorption Therapy in Critically Ill Patients: Protocol for an International, Prospective Registry [PDF]

JMIR Research Protocols
BackgroundExtracorporeal blood purification with CytoSorb has been increasingly used as an adjunctive therapy in several hyperinflammatory critical care conditions, as well as to remove elevated levels of myoglobin or bilirubin in
Fabio Silvio Taccone, Frank Martin Brunkhorst, Gabriella Bottari, Jorge Hidalgo, Andreas Kribben, Jean-Louis Teboul, Dana Tomescu, Teresa Klaus, Joerg Scheier, Efthymios Deliargyris, Ricard Ferrer   +10 more
doaj   +2 more sources

Excessive Apixaban Concentrations in a Bleeding Patient Treated With Pharmacological Reversal and Extracorporal Removal-A Case Report. [PDF]

Pharmacol Res Perspect
Excessive apixaban concentrations in a bleeding patient leading to impaired coagulation and treatment with pharmacological reversal and extracorporal removal. ABSTRACT In trauma, even therapeutic apixaban levels can significantly exacerbate bleeding.
Kraus RF, Rosenberger J, Dejaco A, Paal M, Hart C, Burkhardt R, Kees MG.   +6 more
europepmc   +2 more sources

COVID-19: Hyperinflammatory Syndrome and Hemoadsorption with CytoSorb [PDF]

Blood Purification, 2020
Following the emergence of a novel coronavirus from Wuhan, China, the world faced a major problem, so many countries were shocked by the outbreak of this virus. Unlike the rest of its dangerous family, it has a higher reproductive number than Middle East respiratory syndrome, which is estimated to be approximately 3.28 with a median of 2.79 and IQR of ...
Behnam, Masmouei, Mehdi, Harorani, Mohammad-Rafi, Bazrafshan, Zahra, Karimi   +3 more
openaire   +2 more sources

Pharmacokinetics of anti-infective agents during CytoSorb hemoadsorption [PDF]

Scientific Reports, 2021
AbstractCytokine hemoadsorption might be beneficial in patients with sepsis. However, its effect on anti-infective agents' disposition remains largely unknown. We sought to determine the influence of hemoadsorption on the pharmacokinetics of common anti-infective agents.
Schneider, A.G., André, P., Scheier, J., Schmidt, M., Ziervogel, H., Buclin, T., Kindgen-Milles, D.   +6 more
openaire   +4 more sources

Cytosorb® haemoadsorption: a potential game changer for patients needing myocardial surgical revascularisation [PDF]

, 2021
Cytosorb, an extracorporeal blood purification system, utilises the principles of haemoadsorption to remove low molecular weight substances from the blood, including multiple cytokines such as interleukin (IL)-1b, IL-6, IL-8, and tumour necrosis factor-α,
Marczin, Nandor, Stock, Ulrich A, Umakumar, Kabeer, Ng Yin Ling, Clarissa, Raja, Shahzad G, de Waal, Eric EC, Moss, Louise   +6 more
core   +1 more source

A case report to highlight the impact of extracorporeal cytokine elimination therapy in viper snakebite induced septic shock with acute kidney injury [PDF]

International Journal of Medical Device and Adjuvant Treatments, 2020
Introduction: Snakebite envenomation can lead to prolonged disruption of hemostasis, neuromuscular paralysis, myolysis (muscle degeneration) followed by release of damage associated molecular patterns, acute kidney injury and hypovolaemic shock due to ...
K. Parikh, H. Patel, M. Kothari, L. Maheshwari, V. Shetty, S. Khadke   +5 more
doaj   +1 more source

Hemoadsorption in the critically ill—Final results of the International CytoSorb Registry [PDF]

PLOS ONE, 2022
The aim of the current paper is to summarize the results of the International CytoSorb Registry. Data were collected on patients of the intensive care unit. The primary endpoint was actual in-hospital mortality compared to the mortality predicted by APACHE II score.
Fatime Hawchar, Dana Tomescu, Karl Träger, Dominik Joskowiak, Klaus Kogelmann, Jens Soukup, Singrun Friesecke, David Jacob, Jan Gummert, Andreas Faltlhauser, Filippo Aucella, Martijn van Tellingen, Manu L. N. G. Malbrain, Ralph Bogdanski, Günter Weiss, Andreas Herbrich, Stefan Utzolino, Axel Nierhaus, Andreas Baumann, Andreas Hartjes, Dietrich Henzler, Evgeny Grigoryev, Harald Fritz, Friedhelm Bach, Stefan Schröder, Andreas Weyland, Udo Gottschaldt, Matthias Menzel, Olivier Zachariae, Radovan Novak, Jernej Berden, Hendrik Haake, Michael Quintel, Stephan Kloesel, Andreas Kortgen, Stephanie Stecher, Patricia Torti, Frieder Nestler, Markus Nitsch, Detlef Olboeter, Philip Muck, Michael Findeisen, Diane Bitzinger, Jens Kraßler, Martin Benad, Martin Schott, Ulrike Schumacher, Zsolt Molnar, Frank Martin Brunkhorst   +48 more
openaire   +6 more sources

Impact of Cytosorb hemofilter on heart transplant outcomes

, 2023
Cilj istraživanja. Istraživanje ispituje hipotezu da Cytosorb hemofilter smanjuje potrebu za transfuzijama krvnih derivata tijekom i nakon transplantacije srca.
Singer, Sarah
core   +2 more sources