Downregulation of Tumor Necrosis Factor Expression in the Human Mono-Mac-6 Cell Line [PDF]
Mono-Mac-6 cells, but not U937 cells, can be Induced to rapidly express tumor necrosis factor (TNF) mRNA and protein when triggered with Ilpopolysaccharlde (LPS) at 1 pg/mI. Preincubatlon of the cells for 3 d with low amounts of LPS (10 ng/mI) results In
Blömer, Kathi +5 more
core +1 more source
ABSTRACT Background Folate receptor‐⍺ (FR‐⍺) is an attractive target for targeted therapy. Mirvetuximab soravtansine (MIRV) has been approved by the United States Food and Drug Administration (FDA) for treating adult patients with FR‐⍺ positive, platinum‐resistant epithelial ovarian cancer, fallopian tube cancer, or primary peritoneal cancer. Therefore,
Yadan Ma +5 more
wiley +1 more source
A novel method for sample preparation of fresh lung cancer tissue for proteomics analysis by tumor cell enrichment and removal of blood contaminants [PDF]
Background In-depth proteomics analyses of tumors are frequently biased by the presence of blood components and stromal contamination, which leads to large experimental variation and decreases the proteome coverage.
Luigi De Petris +6 more
core +2 more sources
Induced sputum is a reproducible method to assess airway inflammation in asthma
To evaluate the reproducibility of induced sputum analysis, and to estimate the sample size required to obtained reliable results, sputum was induced by hypertonic saline inhalation in 29 asthmatic subjects on two different days.
Elena Bacci +8 more
doaj +1 more source
Neutrophils are known to perform a series of effector functions that are crucial for the innate and adaptive responses, including the synthesis and secretion of a variety of cytokines.
Nicola Tamassia +14 more
doaj +1 more source
IL‐33 Elicits LTC4 Synthesis in Allergic Inflammation via ST2‐Mediated Activation of Eosinophils
Allergic reaction‐derived IL‐33 activates ST2 to trigger selective eosinophil activation. IL‐33 in a type 2 immune response environment induces biogenesis of lipid bodies in eosinophils, platforms for the generation of lipid mediators, and selectively triggers LTC4 production.
Vitória F. Rosário‐Garcia +11 more
wiley +1 more source
Citologías cérvico vaginales procesadas en medio líquido: Comparación con las convencionales
Objetivo: evaluar la calidad de la muestra procesada en medio líquido en comparación al método convencional. Métodos: se realizó un análisis observacional descriptivo en el cual fueron estudiadas 32 citologías cérvico vaginales (CCV) de pacientes que ...
Juan Pablo Blanco +3 more
doaj +1 more source
Immunocytochemical Analysis of Human Pluripotent Stem Cells using a Self-Made Cytospin Apparatus [PDF]
Human pluripotent stem cells (hPSCs) that include human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs) are exciting cell sources due to their limitless self-renewal capabilities and their potential to differentiate into multiple cell types.
Enrique Y, Pascual +2 more
openaire +2 more sources
ABSTRACT Human parainfluenza viruses (HPIVs) commonly cause croup and lower respiratory tract infections in young children. Despite typically self‐limiting with mild symptoms, the innate immune responses to HPIVs remain poorly understood, especially across all four types in human nasal epithelial cells (hNECs), the primary infection site.
Hsiao Hui Ong +6 more
wiley +1 more source
Ibrutinib impairs the phagocytosis of rituximab-coated leukemic cells from chronic lymphocytic leukemia patients by human macrophages [PDF]
We have read with great interest the recent article of Kohrt, H.E. et al1 showing that Ibrutinib prevented NK cell mediated cytotoxicity of antibody-coated CLL cells in vitro.
Almejún, María Belén +8 more
core +2 more sources

