Results 41 to 50 of about 685,272 (267)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Blinatumomab, a CD19xCD3 bispecific T‐cell engager, has become standard therapy for children with de novo B‐cell acute lymphoblastic leukemia (B‐ALL). This retrospective review describes the experience of blinatumomab administration in pediatric patients.
Julia M. Hurley +6 more
wiley +1 more source
Indonesian Journal of ChemistryMangrove-associated endophytic fungi are producers of secondary metabolites in unique and diverse structures with interesting biological activities such as antiviral, antifungal, antibacterial, anti-inflammatory, and cytotoxic agents.
Yeni Mulyani +10 more
doaj +1 more source
Synthesis of New Cytotoxic Aminoanthraquinone Derivatives via Nucleophilic Substitution Reactions
Molecules, 2013 Aminoanthraquinones were successfully synthesized via two reaction steps. 1,4-Dihydroxyanthraquinone (1) was first subjected to methylation, reduction and acylation to give an excellent yield of anthracene-1,4-dione (3), 1,4-dimethoxyanthracene-9,10 ...
Hasimah Alimon +5 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT We report a retrospective single‐center analysis of pediatric patients with relapsed or refractory B‐cell precursor acute lymphoblastic leukemia focusing on relapses outside of the typical locations, bone marrow, central nervous system, or testes.
Johanna Kunz +7 more
wiley +1 more source
Cytotoxic activity of Isatis campylocarpa, an Iranian endemic plant, on human cancer cell lines [PDF]
Journal of Cell and Molecular Research, 2009 The antineoplastic activities of alcoholic and aqueous extracts of the roots, stems and leaves of Isatis campylocarpa an endemic species of the Brassicaceae family from Iran, investigated on the growth of Jurkat as an acute lymphocytic leukemia cell line,
Sasan Mohsenzadeh +3 more
doaj +1 more source
Hog plums: Its importance, potentials and future prospects
Notulae Scientia Biologicae, 2021 Hog plums, scientifically known as Spondias mombin are medicinal plants that are rich in nutrients and antioxidants, and are of great importance in the food/agricultural industries and the health sector.
Hilda A. EMMANUEL-AKERELE +2 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Molecules, 2014 For many years, several studies have been employing lectin from vegetables in order to prove its toxic effect on various cell lines. In this work, we analyzed the cytotoxic, antiproliferative, and post-incubatory effect of pure tepary bean lectins on ...
Carmen Valadez-Vega +7 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Molecules, 2014 The present work describes the phytochemical study on Ferula lutea flowers. Total phenolics and flavonoids of the n-butanol and ethyl acetate extracts were quantified (phenolics [40.68–52.29 mg gallic acid equivalent/g of dry weight], flavonoids [12.38 ...
Mansour Znati +3 more
doaj +1 more source