Results 21 to 30 of about 685,272 (267)
Granzymes in health and diseases: the good, the bad and the ugly
Frontiers in ImmunologyGranzymes are a family of serine proteases, composed of five human members: GA, B, H, M and K. They were first discovered in the 1980s within cytotoxic granules released during NK cell- and T cell-mediated killing.
Lavinia Cigalotto +3 more
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Biomolecules, 2020 Lauraceae species are known as excellent essential oil (EO) producers, and their taxa are distributed throughout the territory of Brazil. This study presents a systematic review of chemical composition, seasonal studies, occurrence of chemical profiles ...
Júlia Karla A. M. Xavier +3 more
doaj +1 more source
Mechanism of cytotoxicity of paraquat [PDF]
Environmental Health and Preventive Medicine, 2002 Acute paraquat poisoning seems to be very complex because many possible mechanisms of paraquat cytotoxicity have been reported. Some may not be the cause of paraquat poisoning but the result or an accompanying phenomenon of paraquat action. The mechanism critical for cell damage is still unknown.
FUKUSHIMA, Tetsuhito +3 more
openaire +2 more sources
Frontiers in Chemistry, 2021 A series of bis-thiazoles 5a–g were synthesized from bis-thiosemicarbazone 3 with hydrazonoyl chlorides 4a–g. Reaction of 3 with two equivalents of α-halocarbonyl compounds 6–8, 10, and 12a–d afforded the corresponding bis-thiazolidines 9, 11, and 13a–d,
Kamal M. Dawood +7 more
doaj +1 more source
Acute cyanide Intoxication: A rare case of survival
Indian Journal of Anaesthesia, 2014 A 30-year-old male jewellery factory worker accidentally ingested silver potassium cyanide and was brought to the emergency department in a state of shock and profound metabolic acidosis.
Durga Jethava +4 more
doaj +1 more source
Antioxidant, antibacterial, and cytotoxic activities of different parts of Salsola vermiculata
Biomedical and Biotechnology Research Journal, 2021 Background: Salsola vermiculata is an annual plant which is broadly distributed in southwest of Asia. Due to the lack of data regarding the biological properties of different parts of S.
Saeed Mollaei +4 more
doaj +1 more source
ToxicsBackground/Objectives: The leakage of 5-fluorouracil (5-FU) from elastomeric infusion pumps used in cancer therapy poses a potential risk of unintentional exposure to multiple individuals, including patients’ relatives and healthcare professionals, and ...
Andreia Cardoso +7 more
doaj +1 more source
β-Elemene: Mechanistic Studies on Cancer Cell Interaction and Its Chemosensitization Effect
Frontiers in Pharmacology, 2017 Over the past decade, screening and identifying novel compounds for their biomedical applications has become an upcoming area of research. Identifying the molecular mechanisms of these compounds has become an integral part of anticancer research.
Ziyu Jiang +5 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger +7 more
wiley +1 more source
A cytotoxic ribonuclease. Study of the mechanism of onconase cytotoxicity
Journal of Biological Chemistry, 1993 Onconase, or P-30, is a protein initially purified from extracts of Rana pipiens oocytes and early embryos based upon its anticancer activity both in vitro and in vivo. It is a basic single-chain protein with an apparent molecular mass of 12,000 daltons and is homologous to RNase A.
Y, Wu +4 more
openaire +2 more sources