Results 1 to 10 of about 685,272 (267)

OVX836 Heptameric Nucleoprotein Vaccine Generates Lung Tissue-Resident Memory CD8+ T-Cells for Cross-Protection Against Influenza

Frontiers in Immunology, 2021
Tissue-resident memory (TRM) CD8+ T-cells play a crucial role in the protection against influenza infection but remain difficult to elicit using recombinant protein vaccines.
Judith Del Campo, Julien Bouley, Marion Chevandier, Carine Rousset, Marjorie Haller, Alice Indalecio, Delphine Guyon-Gellin, Alexandre Le Vert, Fergal Hill, Sophia Djebali, Yann Leverrier, Jacqueline Marvel, Béhazine Combadière, Florence Nicolas   +13 more
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Bioactive Secondary Metabolites from the Endophytic Fungi Alternaria sp.

Indonesian Journal of Chemistry, 2022
Shifting the drug discovery from plants to microorganisms due to minimizing the ecological effects has led to the increasing work on finding bioactive metabolites from endophytic fungi, especially those isolated from medicinal plants growing in arid and ...
Antonius Rolling Basa Ola, Dodi Darmakusuma, Luther Kadang, Amor Tresna Karyawati, Sherly Monitha Febriani Ledoh, Imanuel Gauru, Pius Dore Ola, Suwari Suwari, Henderiana Laura Loiusa Belli   +8 more
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Estimation of US patients with cancer who may respond to cytotoxic chemotherapy

Future Science OA, 2020
Aims, patients & methods: In this retrospective review, we sought to estimate the proportion of patients in the USA with advanced or metastatic cancer who are eligible for and may respond to recommended first-line cytotoxic chemotherapy based on National
Edward B Maldonado, Scott Parsons, Emerson Y Chen, Alyson Haslam, Vinay Prasad   +4 more
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Structural Basis of 2-Phenylamino-4-phenoxyquinoline Derivatives as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors

Molecules, 2022
New target molecules, namely, 2-phenylamino-4-phenoxyquinoline derivatives, were designed using a molecular hybridization approach, which was accomplished by fusing the pharmacophore structures of three currently available drugs: nevirapine, efavirenz ...
Arthit Makarasen, Suwicha Patnin, Pongsit Vijitphan, Nanthawan Reukngam, Panita Khlaychan, Mayuso Kuno, Pakamas Intachote, Busakorn Saimanee, Suchada Sengsai, Supanna Techasakul   +9 more
doaj   +1 more source

Plumeria alba-Mediated Green Synthesis of Silver Nanoparticles Exhibits Antimicrobial Effect and Anti-Oncogenic Activity against Glioblastoma U118 MG Cancer Cell Line

Nanomaterials, 2022
Plumeria alba (P. alba) is a small laticiferous tree with promising medicinal properties. Green synthesis of nanoparticles is eco-friendly, cost-effective, and non-hazardous compared to chemical and physical synthesis methods.
Muthuraj Rudrappa, Hassan Ahmed Rudayni, Rasha Assad Assiri, Asmatanzeem Bepari, Dhanyakumara Shivapoojar Basavarajappa, Shashiraj Kariyellappa Nagaraja, Bidhayak Chakraborty, Pallavi Sathyanarayana Swamy, Shekappa Ningappa Agadi, Shaik Kalimulla Niazi, Sreenivasa Nayaka   +10 more
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Cytotoxic CD4 T cells in the mucosa and in cancer

Frontiers in Immunology, 2023
CD4 T cells were initially described as helper cells that promote either the cellular immune response (Th1 cells) or the humoral immune response (Th2 cells).
Hrishi Venkatesh, Hrishi Venkatesh, Sean I. Tracy, Sean I. Tracy, Michael A. Farrar, Michael A. Farrar   +5 more
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Unraveling the Potential of Organic Oregano and Tarragon Essential Oils: Profiling Composition, FT-IR and Bioactivities

Plants, 2023
Oregano and tarragon are widely cultivated culinary herbs used for food seasoning, having familiar characteristic aromas appreciated by the wide public.
Dan Vârban, Marius Zăhan, Ioana Crișan, Carmen Rodica Pop, Emese Gál, Răzvan Ștefan, Ancuța Mihaela Rotar, Adriana Sebastiana Muscă, Ștefania Dana Meseșan, Vasile Horga, Ioan Ladoși, Loredana Olar, Andrei Stoie, Rodica Vârban   +13 more
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Cytotoxicity of Dendrimers [PDF]

Biomolecules, 2019
Drug delivery systems are molecular platforms in which an active compound is packed into or loaded on a biocompatible nanoparticle. Such a solution improves the activity of the applied drug or decreases its side effects. Dendrimers are promising molecular platforms for drug delivery due to their unique properties.
Anna Janaszewska, Joanna Lazniewska, Przemysław Trzepiński, Monika Marcinkowska, Barbara Klajnert-Maculewicz   +4 more
openaire   +3 more sources

Triterpenes and Phenolic Compounds from the Fungus Fuscoporia torulosa: Isolation, Structure Determination and Biological Activity

Molecules, 2021
Investigation of the methanol extract of the poroid fungus Fuscoporia torulosa resulted in the isolation of a novel triterpene, fuscoporic acid (1), together with inoscavin A and its previously undescribed Z isomer (2 and 3), 3,4-dihydroxy-benzaldehide ...
Zoltán Béni, Miklós Dékány, András Sárközy, Annamária Kincses, Gabriella Spengler, Viktor Papp, Judit Hohmann, Attila Ványolós   +7 more
doaj   +1 more source

Chemical Analysis, Toxicity Study, and Free-Radical Scavenging and Iron-Binding Assays Involving Coffee (Coffea arabica) Extracts

Molecules, 2021
We aimed to analyze the chemical compositions in Arabica coffee bean extracts, assess the relevant antioxidant and iron-chelating activities in coffee extracts and instant coffee, and evaluate the toxicity in roasted coffee.
Nuntouchaporn Hutachok, Pimpisid Koonyosying, Tanachai Pankasemsuk, Pongsak Angkasith, Chaiwat Chumpun, Suthat Fucharoen, Somdet Srichairatanakool   +6 more
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