Results 101 to 110 of about 11,083,244 (410)
Anti-CD20 Therapy Acts via FcγRIIIA to Diminish Responsiveness of Human Natural Killer Cells [PDF]
, 2015 Natural killer (NK) immune cells mediate antibody-dependent cellular cytotoxicity (ADCC) by aggregating FcγRIIIA/CD16, contributing significantly to the therapeutic effect of CD20 monoclonal antibodies (mAb).
Capuano, Cristina +8 more
core +1 more source
Antimycobacterial and cytotoxicity activity of microcystins [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2015 The present work aimed to evaluate the antimycobacterial activity and cytotoxicity of Microcystis aeruginosa toxins, the MC-LR variant and purified extract of [D-Leu(1)] microcystin-LR.The antimicrobial activity of M. aeruginosa extract and microcystin was evaluated by resazurin microtiter assay against Mycobacterium tuberculosis, M.
Ramos, Daniela Fernandes +6 more
openaire +5 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Synthesis and cytotoxicity evaluation of thiosemicarbazones and their thiazole derivatives
Brazilian Journal of Pharmaceutical SciencesThe aims of this study were to synthesize a series of thiosemicarbazones and their thiazole derivatives, to investigate their cytotoxic activity against three human cancers and normal (Vero cells) cell lines, and to evaluate the pro-apoptotic potential ...
Saulo Feheiberg Pinto Braga +4 more
doaj +1 more source
Cytotoxic Activity of Some Azole Derivatives
Asian Pacific Journal of Cancer Biology, 2018 Azole derivatives are an important class of compounds in medicinal chemistry with a wide variety of biological activities. We previously described synthesis and antimicrobial evaluations of some new Azole derivatives.
Zeinab Faghih +4 more
doaj +1 more source
Antioxidant and Cytotoxic Activity of Hydroethanolic Extract from Jacaranda decurrens Leaves
PLoS ONE, 2014 Background and Purpose Leaves of Jacaranda decurrens are used in traditional Brazilian medicine to treat metabolic diseases related to increased reactive oxygen species.
Junior César Casagrande +12 more
semanticscholar +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Química Nova, 2016 Specimens of Leonotis nepetiflolia were obtained from cultivated and wild environments to verify their influences in chemical composition. Phytochemical analyses were conducted for the ethyl acetate phase obtained by partitioning the crude ethanol ...
Ana P. Oliveira +15 more
doaj +1 more source
Antioxidant and Cytotoxic Activities of Kudzu Roots and Soy Molasses against Pediatric Tumors and Phytochemical Analysis of Isoflavones Using HPLC-DAD-ESI-HRMS [PDF]
, 2022 Saied A. Aboushanab +7 more
openalex +1 more source
Gene Therapy for Pediatric Cancer: State of the Art and Future Perspectives [PDF]
, 2003 While modern treatments have led to a dramatic improvement in survival for pediatric malignancy, toxicities are high and a significant proportion of patients remain resistant.
Biagi, Ettore +3 more
core +5 more sources