Results 131 to 140 of about 602,582 (313)
Biological activities of ethanolic extracts from deep-sea antarctic marine sponges
, 2013 We report on the screening of ethanolic extracts from 33 deep-sea Antarctic marine sponges for different biological activities. We monitored hemolysis, inhibition of acetylcholinesterase, cytotoxicity towards normal and transformed cells and growth ...
Jerneja Avguštin +20 more
core +1 more source
, 2020 A family of original bis(artemisinin-NHC)gold(I) complexes have been synthesized. These hybrid molecules combine two biological active motifs, an artemisinin derivative (DHA) and a cationic bis(NHC)gold(I) unit.
Marie-Lise, Maddelein +10 more
core +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
Evidence of HIV-1 adaptation to HLA-restricted immune responses at a population level
, 2002 Selection of HIV-1 variants resistant to antiretroviral therapy is well documented. However, the selection in vivo of HIV-1 mutant species that can escape host immune system HLA class I restricted cytotoxic T-lymphocyte responses has, to date, only been ...
Moore, Corey Benjamin
core
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Cytotoxic Activity in Freshwater Sponges
, 2007 Cytotoxic compounds, presumably functioning in defense against predators, parasites, and infectious organisms, are produced or sequestered by a variety of invertebrate animals.
Bania, Buck
core
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Synthesis and cytotoxic activity of sulfur linked mono / bis heterocycles [PDF]
, 2018 1173-1178A variety of sulfur linked mono / bis heterocycles have been prepared and their cytotoxic activity on A549 lung adenocarcinoma cells studied. The imidazolyl and benzimidazolyl thiadiazoles (7c, 8c) display appreciable cytotoxic activity against ...
Padmavathi, Venkatapuram +4 more
core
Cytotoxic effects of selective species of Caryophyllaceae in Iran [PDF]
Research Journal of Pharmacognosy, 2014 Cancer is a major cause of death worldwide and causes serious problems in human life. It is developed by uncontrolled growth of a cell or a group of cells.
F. Naghibi +4 more
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