Results 11 to 20 of about 11,083,244 (410)
Cytotoxic activity in cutaneous leishmaniasis [PDF]
Memorias do Instituto Oswaldo Cruz, 2017 Cutaneous leishmaniasis (CL) is a chronic disease caused by species of the protozoan Leishmania and characterised by the presence of ulcerated skin lesions. Both parasite and host factors affect the clinical presentation of the disease.
Taís M Campos +3 more
doaj +3 more sources
Synthesis and biological activity of novel zingerone-thiohydantoin hybrids [PDF]
Journal of the Serbian Chemical Society, 2022 A series of zingerone–thiohydantoin hybrids were synthesized from O-alkyl zingerone derivatives by cyclocondensation with thiosemicarbazide in a two-step reaction. The obtained new potentially bioactive compounds were structurally characterized by IR and
Virijević Katarina D. +6 more
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In Vitro Cytotoxic Activity of African Plants: A Review
Molecules, 2022 In African countries, cancer not only is a growing problem, but also a challenge because available funding and resources are limited. Therefore, African medicinal plants play a significant role in folk medicine and some of them are traditionally used for
I. Canga +4 more
semanticscholar +1 more source
Journal of Enzyme Inhibition and Medicinal Chemistry, 2021 In the current study, new thienopyrimidine conjugates bearing 1,2,3-triazole core and different sugar moieties have been designed and synthesized by Cu(I)-catalysed click dipolar cycloaddition. The cytotoxic activity of the synthesised conjugates 2, 5, 7,
R. Khattab +7 more
semanticscholar +1 more source
Traditional varieties and wild pear from Serbia: a link among antioxidant, antidiabetic and cytotoxic activities of fruit peel and flesh [PDF]
Botanica Serbica, 2021 This study was aimed at evaluating the antioxidant and antidiabetic activities of methanolic extracts of peel, flesh and mixed peel, and flesh, as well as the cytotoxic activity of mixed peel and flesh extracts obtained from fruits of six traditional ...
Mariana Oalđe Pavlović +6 more
doaj +1 more source
Cytotoxic Activity of Orsellinates [PDF]
Zeitschrift für Naturforschung C, 2006 Abstract The series of 2,4-dihydroxy-6-methylbenzoates 2-10 (methyl to hexyl orsellinates) prepared by alcoholysis of lecanoric acid (1) - a natural product from the lichen Parmotrema tinctorum (Nyl.) Hale - was submitted to the brine shrimp lethality test (BST), which was also performed for 2,4-dihydroxy-6-methylbenzoic acid (11 ...
Alcir T, Gomes +4 more
openaire +2 more sources
In vitro assessment of the cytotoxic effects of novel RGD analogues [PDF]
BioDiscovery, 2012 The RGD sequence is present in many extracellular matrix proteins and intracellular proteins, including caspases. Synthetic RGD peptides may affect adhesion, migration and tumour metastasis, or directly induce apoptosis.
Anelia Balacheva +5 more
doaj +3 more sources
Fullerenyl-1,2,3-Triazoles: Synthesis and Cytotoxic Activity
Chemistry Proceedings, 2021 Through the reaction of fullerenylazide with terminal acetylenes, previously undescribed 1-butyl-2-triazolylfullerenes, in which the heterocyclic fragment was directly attached to the fullerene backbone, were synthesized for the first time. Water-soluble
Zarema R. Sadretdinova +5 more
doaj +1 more source
Materials, 2020 Natural carboxylic acids are plant-derived compounds that are known to possess biological activity. The aim of this review was to compare the effect of structural differences of the selected carboxylic acids (benzoic acid (BA), cinnamic acid (CinA), p ...
B. Godlewska-Żyłkiewicz +8 more
semanticscholar +1 more source
Molbank, 2023 An efficient method for the synthesis of 3-(1H-indol-3-yl)-2-(7,8,12,13-tetraoxa-10-azaspiro[5.7]tridecan-10-yl)propanoic acid) via condensation of 7,8,10,12,13-pentaoxaspiro[5.7]tridecane with tryptophan under the action of a catalyst based on Sm(NO3)3 ...
Nataliya N. Makhmudiyarova +3 more
doaj +1 more source