Results 11 to 20 of about 862,062 (313)

Cytotoxic activity in cutaneous leishmaniasis [PDF]

Memorias do Instituto Oswaldo Cruz, 2017
Cutaneous leishmaniasis (CL) is a chronic disease caused by species of the protozoan Leishmania and characterised by the presence of ulcerated skin lesions. Both parasite and host factors affect the clinical presentation of the disease.
Taís M Campos, Rúbia Costa, Sara Passos, Lucas P Carvalho   +3 more
doaj   +3 more sources

Synthesis and biological activity of novel zingerone-thiohydantoin hybrids [PDF]

Journal of the Serbian Chemical Society, 2022
A series of zingerone–thiohydantoin hybrids were synthesized from O-alkyl zingerone derivatives by cyclocondensation with thiosemicarbazide in a two-step reaction. The obtained new potentially bioactive compounds were structurally characterized by IR and
Virijević Katarina D., Stanić Petar B., Muškinja Jovana M., Katanić-Stanković Jelena S., Srećković Nikola, Živanović Marko N., Šmit Biljana M.   +6 more
doaj   +1 more source

Traditional varieties and wild pear from Serbia: a link among antioxidant, antidiabetic and cytotoxic activities of fruit peel and flesh [PDF]

Botanica Serbica, 2021
This study was aimed at evaluating the antioxidant and antidiabetic activities of methanolic extracts of peel, flesh and mixed peel, and flesh, as well as the cytotoxic activity of mixed peel and flesh extracts obtained from fruits of six traditional ...
Mariana Oalđe Pavlović, Ana Alimpić Aradski, Aleksandra Savić, Smiljana Janković, Milena Milutinović, Petar D. Marin, Sonja Duletić-Laušević   +6 more
doaj   +1 more source

Cytotoxic Activity of Orsellinates [PDF]

Zeitschrift für Naturforschung C, 2006
Abstract The series of 2,4-dihydroxy-6-methylbenzoates 2-10 (methyl to hexyl orsellinates) prepared by alcoholysis of lecanoric acid (1) - a natural product from the lichen Parmotrema tinctorum (Nyl.) Hale - was submitted to the brine shrimp lethality test (BST), which was also performed for 2,4-dihydroxy-6-methylbenzoic acid (11 ...
Alcir T, Gomes, Neli K, Honda, Fernanda M, Roese, Rozanna M, Muzzi, Leandro, Sauer   +4 more
openaire   +2 more sources

In vitro assessment of the cytotoxic effects of novel RGD analogues [PDF]

BioDiscovery, 2012
The RGD sequence is present in many extracellular matrix proteins and intracellular proteins, including caspases. Synthetic RGD peptides may affect adhesion, migration and tumour metastasis, or directly induce apoptosis.
Anelia Balacheva, Ivan Iliev, Roumyana Detcheva, Tatyana Dzimbova, Tamara Pajpanova, Evgeny Golovinsky   +5 more
doaj   +3 more sources

Fullerenyl-1,2,3-Triazoles: Synthesis and Cytotoxic Activity

Chemistry Proceedings, 2021
Through the reaction of fullerenylazide with terminal acetylenes, previously undescribed 1-butyl-2-triazolylfullerenes, in which the heterocyclic fragment was directly attached to the fullerene backbone, were synthesized for the first time. Water-soluble
Zarema R. Sadretdinova, Arslan R. Akhmetov, Lilya U. Dzhemileva, Vladimir A. D’yakonov, Airat Tuktarov, Usein Dzhemilev   +5 more
doaj   +1 more source

(3-(1H-Indol-3-yl)-2-(7,8,12,13-tetraoxa-10-azaspiro[5.7]tridecan-10-yl)propanoic acid) with Cytotoxic Activity

Molbank, 2023
An efficient method for the synthesis of 3-(1H-indol-3-yl)-2-(7,8,12,13-tetraoxa-10-azaspiro[5.7]tridecan-10-yl)propanoic acid) via condensation of 7,8,10,12,13-pentaoxaspiro[5.7]tridecane with tryptophan under the action of a catalyst based on Sm(NO3)3 ...
Nataliya N. Makhmudiyarova, Irina R. Ishmukhametova, Lilya U. Dzhemileva, Usein M. Dzhemilev   +3 more
doaj   +1 more source

Evaluation of analgesic, antioxidant and cytotoxic activities of ethanol extract of Clerodendrum viscosum Vent

Journal of Applied Pharmaceutical Research, 2021
Clerodendrum viscosum Vent. is a very common plant in Bangladesh which is locally familiar as “Bhat” or “Ghetu”. Here, the ethanol extract of whole plant part of C.
Sujan Chandra Das, Md. Ruhul Kuddus, Nazmul Qais, Choudhury M. Hasan   +3 more
doaj   +1 more source

Chemical modifications of a natural xanthone and antimicrobial activity against multidrug resistant Staphylococcus aureus and cytotoxicity against human tumor cell lines

Química Nova, 2011
A series of 15 ω-aminoalkoxylxanthones containing methyl, ethyl, propyl, tert-butylamino and piperidinyl moieties were synthesized from a natural xanthone isolated from a lichen species.
Ana Camila Micheletti, Neli Kika Honda, Dênis Pires de Lima, Adilson Beatriz, Maria Rita Sant'ana, Nadia Cristina Pereira Carvalho, Maria de Fatima Cepa Matos, Lyara Meira Marinho Queiróz, Danielle Bogo, José Roberto Zorzatto   +9 more
doaj   +1 more source

CD300LG improves the cytotoxic activity of CIK

Central European Journal of Immunology, 2017
To investigate the effect of CD300LG-γ induction on the cytotoxic activity of CIK. Eukaryotic expression plasmid hCD300LG-γ/pEGFP-C3, which can express human CD300LG-γ, was constructed and transfected into CHO cells by lipofectamine.
Qiuyue Wang, Yuqing Liu, Ying Chen, Ke Wang, Wensheng Xie, Dapeng Wei, Lijuan Hu   +6 more
doaj   +1 more source