Results 61 to 70 of about 11,083,244 (410)

Green Synthesis of Zinc Oxide Nanoparticles Using Aqueous Extract of Deverra tortuosa and their Cytotoxic Activities

Scientific Reports, 2020
In recent years, there is a growing interest towards the green synthesis of metal nanoparticles, particularly from plants; however, yet no published study on the synthesis of ZnO.NPs using the Deverra tortuosa extract.
Y. Selim, Maha A Azb, Islam Ragab, Mohamed H. M. Abd El-Azim   +3 more
semanticscholar   +1 more source

Phytochemical composition and cytotoxic activity of four Cousinia Species against human hepatocellular carcinoma (HepG2) cell line

Phytomedicine Plus, 2021
Background: Cousinia Cass. is one of the most diverse genus of Asteraceae family. According to previous studies some Cousinia species showed significant cytotoxic activity.
Leyla Paşayeva, Eren Demirpolat, Hanifa Fatullayev, Osman Tugay   +3 more
doaj   +1 more source

Role of surface charge and oxidative stress in cytotoxicity of organic monolayer-coated silicon nanoparticles towards macrophage NR8383 cells [PDF]

, 2010
Background - Surface charge and oxidative stress are often hypothesized to be important factors in cytotoxicity of nanoparticles. However, the role of these factors is not well understood.
Alink, G.M., Bhattacharjee, S., Evers, N.M., Haan, L.H.J., de, Jiang, X., Marcelis, A.T.M., Rietjens, I.M.C.M., Zuilhof, H.   +7 more
core   +2 more sources

New acetylenic derivatives of betulin and betulone, synthesis and cytotoxic activity

Medicinal Chemistry Research, 2016
Betulin 1 and its semisynthetic derivatives exhibit a cytotoxic activity toward various cancer cell lines. These compounds are a promising and potential anticancer candidates.
E. Bębenek, Monika Kadela-Tomanek, E. Chrobak, J. Wietrzyk, J. Sadowska, S. Boryczka   +5 more
semanticscholar   +1 more source

Cytotoxic Activities and Structure-Cytotoxic Relationships of Steroidal Saponins.

Biological and Pharmaceutical Bulletin, 2001
We have systematically examined the cytotoxic activities of the steroidal saponins mainly isolated from the Liliaceae plants against HL-60 human promyelocytic leukemia cells and found several structure-activity relationships. Some steroidal saponins evaluated in the assay system showed considerable cytotoxic activities, which were almost as potent as ...
Y, Mimaki, A, Yokosuka, M, Kuroda, Y, Sashida   +3 more
openaire   +3 more sources

Pazopanib Combined With Vincristine and Irinotecan in Relapsed Wilms Tumor: Encouraging Outcomes in a Heavily Pretreated Pediatric Cohort

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale, Alessandro Crocoli, Giuseppe Maria Milano, Pierluigi Di Paolo, Francesca Diomedi Camassei, Ida Russo, Annalisa Serra   +6 more
wiley   +1 more source

Cytotoxic Activity of Ascidian Eudistoma SP. From Mantehage Island Manado [PDF]

, 2014
Koloni Ascidian genus Eudistoma telah dikoleksi dari perairan Pulau Mantehage, Sulawesi Utara Indonesia. Ekstrak kasar metanolik dari Eudistoma sp. yang diuji sitotoksisitasnya terhadap koloni hamster China (V79) memperlihatkan aktivitas sitotoksik yang ...
Paruntu, C. P. (Carolus), Rotinsulu, H. (Henki), Rumampuk, N. D. (Natalie), Sumilat, D. A. (Deiske), Wewengkang, D. S. (Defny)   +4 more
core  

Natural killer cell response to chemotherapy-stressed cancer cells: Role in tumor immunosurveillance. [PDF]

, 2017
Natural killer (NK) cells are innate cytotoxic lymphoid cells that actively prevent neoplastic development, growth, and metastatic dissemination in a process called cancer immunosurveillance.
Borrelli, Cristiana, Cippitelli, Marco, Fionda, Cinzia, Santoni, Angela, Soriani, Alessandra, Zingoni, Alessandra   +5 more
core   +1 more source

Flavonoid Compounds from the Leaves of Kalanchoe prolifera and Their Cytotoxic Activity against P-388 Murine Leukimia Cells

, 2017
− Seven flavonoid compounds, kaempferol (1), quercetin (2), quercetin-3-O-β-D-glucopyranoside (3), kaempferol-3-O-β-D-glucopyranoside (4), kaempferol-3-O-α-L-rhamnoside (5), quercetin-3-O-sophoroside (6) and quercetin-3-O-rutinoside (7), were isolated ...
L. Aisyah, Y. Yun, T. Herlina, E. Julaeha, A. Zainuddin, Ida Nurfarida, A. Hidayat, U. Supratman, Y. Shiono   +8 more
semanticscholar   +1 more source

Axitinib induces senescence-associated cell death and necrosis in glioma cell lines: The proteasome inhibitor, bortezomib, potentiates axitinib-induced cytotoxicity in a p21(Waf/Cip1) dependent manner. [PDF]

, 2017
Glioblastoma is associated with a poor overall survival despite new treatment advances. Antiangiogenic strategies targeting VEGF based on tyrosine kinase inhibitors (TKIs) are currently undergoing extensive research for the treatment of glioma.
Amantini, C, BERNARDINI, Giovanni, CARDINALI, CLAUDIO, MORELLI, MARIA BEATRICE, Nabissi, M, SANTONI, Angela, Santoni, G., Santoni, M   +7 more
core   +1 more source