Results 1 to 10 of about 710,484 (321)
Cell, 1993 Much of immunology is concerned with the nature and consequences of interactions between cells. The T lymphocyte effecters of cell-mediated immunity (CMI) are highly motile, do not maintain stable anatomical relationships, and express an enormous range of cell-surface receptors that determine (among other functions) both antigen specificity and ...
openaire +2 more sources
Effects of space structure and combination therapies on phenotypic heterogeneity and drug resistance in solid tumors [PDF]
arXiv, 2013 Histopathological evidence supports the idea that the emergence of phenotypic heterogeneity and resistance to cytotoxic drugs can be considered as a process of adaptation, or evolution, in tumor cell populations. In this framework, can we explain intra-tumor heterogeneity in terms of cell adaptation to local conditions?
arxiv
Cytotoxic T cells: Lyt phenotype and blocking of killing activity by Lyt antisera [PDF]
, 1979 Eiichi Nakayama +4 more
openalex +1 more source
Role of viral infectivity in the induction of influenza virus-specific cytotoxic T cells. [PDF]
, 1978 T J Braciale, K. L. Yap
openalex +1 more source
Immune-Mediated Cytotoxicity in Inflammatory Bowel Disease
Canadian Journal of Gastroenterology, 1990 Thirty years of research on the role of immune-mediated cytotoxic activity in the tissue injury of inflammatory bowel disease (IBD) has yielded only inconclusive data on the relevance of cytotoxic mechanisms. Two hypotheses have been advanced.
Stephan R Targan +2 more
doaj +1 more source
cell surface glycoproteins of murine cytotoxic T lymphocytes. I. T 145, a new cell surface glycoprotein selectively expressed on Ly 1-2(+) cytotoxic T lymphocytes [PDF]
, 1978 AK Kimura, Hans Wigzell
openalex +1 more source
Assessment of immune response in ICU admitted SARS-CoV-2 patients from Kashmir, North India [PDF]
Journal of Research in Applied and Basic Medical SciencesBackground & Aims: The present study aimed to investigate the lymphocyte subpopulation counts (Th, Tc, B-cell, and NK cell) in SARS-CoV-2 patients (admitted to the ICU) to gain greater insight into the dysregulated immune response found in COVID-19 ...
Iqra Farooq +8 more
doaj
Сеченовский вестникAim. To evaluate the antitumor efficacy of our developed drug based on cytotoxic T lymphocytes genetically modified with a chimeric antigen receptor (CAR) specific to the CA125 antigen in relation to both CA125-positive and CA125negative cell cultures ...
T. M. Kulinich +7 more
doaj +1 more source
Immune dysregulation in immunoglobulin G4–related disease
Japanese Dental Science Review, 2023 (IgG4-RD) is an immune-mediated fibrotic disorder characterized by severe resolution of inflammation and dysregulation of wound healing. IgG4-RD has been considered a unique disease since 2003, and significant progress has been achieved in the ...
Takashi Maehara +2 more
doaj
OncoImmunologyChimeric antigen receptor (CAR) T cells have demonstrated outstanding therapeutic success in hematological malignancies. Yet, their efficacy against solid tumors remains constrained due to inadequate infiltration of cytotoxic T and CAR-T cells in the ...
Siyue Nie +8 more
doaj +1 more source