The lncRNA <i>Malat1</i> inhibits miR-15/16 to enhance cytotoxic T cell activation and memory cell formation. [PDF]
Wheeler BD +10 more
europepmc +1 more source
Cytotoxic T cells clear virus but augment lung pathology in mice infected with respiratory syncytial virus. [PDF]
Martin J. Cannon +2 more
openalex +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Macrophages foster anti-tumor immunity by ZEB1-dependent cytotoxic T cell chemoattraction. [PDF]
Fuchs K +31 more
europepmc +1 more source
Measles virus-specific T4+ human cytotoxic T cell clones are restricted by class II HLA antigens. [PDF]
Steven Jacobson +5 more
openalex +1 more source
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins +2 more
wiley +1 more source
SLAMF7 (CD319) enhances cytotoxic T-cell differentiation and sensitizes CD8<sup>+</sup> T cells to immune checkpoint blockade. [PDF]
Sander JE +8 more
europepmc +1 more source
Probable Primary Cutaneous CD8+ Aggressive Epidermotropic Cytotoxic T-cell Lymphoma: A Case Report of a Diagnostic Challenge. [PDF]
Velarde Loya M +3 more
europepmc +1 more source

