Results 201 to 210 of about 518,936 (262)

Primary cutaneous aggressive epidermotropic CD8+ cytotoxic T-cell lymphoma with aberrant CD56 expression: a rare case report. [PDF]

Postepy Dermatol Alergol
Luo S, Chen Y, Zhang G.
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Characterization of natural killer and cytotoxic T-cell immune infiltrates in pancreatic ductal adenocarcinoma. [PDF]

J Surg Oncol
Persky J, Cruz SM, Darrow MA, Judge SJ, Li Y, Bold RJ, Karnezis AN, Matsukuma KE, Qi L, Canter RJ.   +9 more
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Bispecific antibody simultaneously targeting AGR2 and PD1 mediates cytotoxic T-cell-induced antitumor response in AGR2-dependent manner and inhibits AGR2-induced PDL1 upregulation. [PDF]

Sci Rep
Roy D, He Y, Wang Y, Xu P, Jin B, Xiao H, Li D, Zhao B.   +7 more
europepmc   +1 more source

Engineering Proteus mirabilis improves antitumor efficacy via enhancing cytotoxic T cell responses. [PDF]

Mol Ther Oncol
Zhang H, Luo Y, Zhao X, Liu X.
europepmc   +1 more source

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Cytotoxic T cells and immunotherapy

Pediatric Radiology, 1998
Promising immunotherapies for viral infections and malignancies reflect the successful, rapid translation of laboratory findings into clinical practice. Fletcher et al. [1] present imaging studies of Epstein-Barr virus (EBV)-associated lymphomas before and after immunotherapy.
G R, Kitchingman, C, Rooney
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Teleost cytotoxic T cells

Fish & Shellfish Immunology, 2019
Cell-mediated cytotoxicity is one of the major mechanisms by which vertebrates control intracellular pathogens. Two cell types are the main players in this immune response, natural killer (NK) cells and cytotoxic T lymphocytes (CTL). While NK cells recognize altered target cells in a relatively unspecific manner CTLs use their T cell receptor to ...
Takuya Yamaguchi, Fumio Takizawa, Mitsuru Furihata, Veronica Soto-Lampe, Johannes M. Dijkstra, Uwe Fischer   +5 more
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Alloreactive cytotoxic T cells. I. Alloreactive and allorestricted cytotoxic T cells

European Journal of Immunology, 1985
AbstractNylon wool‐nonadherent spleen cells from three inbred mouse strains of H‐2k (CBA), H‐2d (BALB/c) and H‐2b (C57BL/6) haplotype were co‐cultured with 2,4,6‐ trinitro‐ phenyl (TNP)‐ modified or nonmodified allogeneic stimulator cells in a limiting dilution system.
J, Reimann, K, Heeg, R G, Miller, H, Wagner   +3 more
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Sensitivity of cytotoxic T cells to T-cell mediated cytotoxicity

Nature, 1974
LYMPHOID cells sensitised against alloantigens can lyse in vitro target cells bearing these alloantigens1,2. In most of the experimental systems using in vivo sensitised cells, T cells (thymus-dependent lymphocytes) are both necessary3 and sufficient4,5 for induction of target cell lysis.
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T-cell-mediated cytotoxicity

Current Opinion in Immunology, 1991
There are two competing theories to explain the mechanism(s) by which cytolytic T lymphocytes kill target cells: granule exocytosis of a pore-forming protein, and contact-induced internal disintegration. Accumulated evidence supports alternative pathways in lymphocytoxicity, possibly reflecting distinct effector functions expressed by different killer ...
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Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells

Nature, 1994
It has been suggested that mutations within immunodominant cytotoxic T-lymphocyte (CTL) epitopes may be exploited by viruses to evade protective immune responses critical for clearance. Viral escape could originate from passive mechanisms, such as mutations within crucial CTL epitopes, either affecting major histocompatibility complex binding or T-cell
Bertoletti, A, Sette, A, Chisari, F. V, Penna, A, Levrero, M, De Carli, M, Fiaccadori, F, FERRARI, Carlo   +7 more
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