Results 201 to 210 of about 831,286 (305)

Parallel 3D Bioprinting on SLIPS‐Microarrays

Advanced Functional Materials, EarlyView.
This work introduces the first truly parallel 3D bioprinting method, enabling both the simultaneous fabrication of hundreds of cell laden hydrogel 3D structures and their HTS in individual liquid compartments. By integrating Digital Light Processing (DLP) stereolithography with functional micropatterns, the platform decouples printing time from array ...
Julius von Padberg, Julian A. Serna, Maike Schliephake, Pavel A. Levkin   +3 more
wiley   +1 more source

<i>In silico</i> prediction of cytotoxic T-cell epitopes from <i>Helicobacter pylori</i> virulence factors using an immunoinformatics approach. [PDF]

BioTechnologia (Pozn)
Chacon DV, Co KA, Enriquez DN, Labarda AL, Manongsong RE, Bragais EK.   +5 more
europepmc   +1 more source

Light Activated Induction of Cuproptosis in Resistant Cancer Cells Using Polymeric BODIPY Nanoparticles for Photoactivated Chemotherapy

Advanced Functional Materials, EarlyView.
This article presents a photo‐responsive nanoparticle platform that precisely triggers copper‐dependent cuproptotic cell death in (drug‐resistant) cancer cells. The system remains stable and inactive in the dark but releases cytotoxic species upon red‐light irradiation, achieving potent activity in drug‐resistant breast cancer cells.
Ricarda Zimmermann, Nicolás Montesdeoca, Johannes Karges   +2 more
wiley   +1 more source

Primary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma initially demonstrating near-complete metabolic response to BV-CHEP. [PDF]

J Dtsch Dermatol Ges
Ng TTW, Frederiks AJ, Iacobelli JF, Chuah HS, Radeski D, Delaney TA.   +5 more
europepmc   +1 more source

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source

Primary Cutaneous CD8-positive Aggressive Epidermotropic Cytotoxic T-cell Lymphoma Complicated by Paraneoplastic Encephalitis. [PDF]

Intern Med
Inoue Y, Tsukamoto T, Mizuhara K, Maekura C, Nakamura T, Okamoto H, Fujino T, Mizutani S, Shimura Y, Maruyama A, Nakanishi M, Tanaka E, Nishida Y, Ishii K, Sonobe Y, Miyagawa-Hayashino A, Kuroda J.   +16 more
europepmc   +1 more source

Photon Avalanching Nanoparticles: The Next Generation of Upconverting Nanomaterials?

Advanced Functional Materials, EarlyView.
This Perspective outlines the mechanistic foundations that enable photon‐avalanche (PA) behavior in lanthanide nanomaterials and contrasts them with emerging application spaces and forward‐looking design strategies. By bridging threshold engineering, energy‐transfer dynamics, and materials engineering, we provide a coherent roadmap for advancing the ...
Kimoon Lee, Yunseo Kim, Hyeong‐ku Jo, Dongjoon Yoon, Byeonghyeok Im, WonJeong Yu, Eui‐Rim On, Changhwan Lee   +7 more
wiley   +1 more source

BH3 mimetics augment cytotoxic T cell killing of acute myeloid leukemia via mitochondrial apoptotic mechanism. [PDF]

Cell Death Discov
Saxena K, Hung SH, Ryu E, Singh S, Zhang Tatarata Q, Zeng Z, Wang Z, Konopleva MY, Yee C.   +8 more
europepmc   +1 more source

Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers

Advanced Functional Materials, EarlyView.
A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley   +1 more source

GP73 reinforces cytotoxic T-cell function by regulating HIF-1α and increasing antitumor efficacy. [PDF]

J Immunother Cancer
Liu J, Feng C, Zhao R, Song H, Huang L, Jiang N, Yang X, Liu L, Duan C, Wan L, Gao Q, Sun L, Hou X, Liu M, Zhang Y, Zhang X, Zhang D, Wang Y, Li Y, Ma X, Zhong H, Min M, Wei C, Cao Y, Yang X.   +24 more
europepmc   +1 more source