Results 221 to 230 of about 2,716,407 (409)

Inhibition of cytotoxic T cell lysis by anti-CD8 monoclonal antibodies: studies with CD3-targeted cytolysis of nominal antigen-negative targets. [PDF]

, 1989
Ralph Quinones, David M. Segal, Pierre A. Henkart, Pilar Pérez, Richard E. Gress   +4 more
openalex   +1 more source

Double‐Stranded DNA Reduces dsRNA Degradation in the Saliva and Significantly Enhanced RNAi‐Mediated Gene Silencing in Halyomorpha halys

Advanced Biology, EarlyView.
The invasive pest Halyomorpha halys causes significant crop losses requiring innovative pest control strategies such as RNA interference (RNAi). However, oral RNAi is largely ineffective in H. halys. This study shows that double‐stranded DNA (dsDNA) stabilizes dsRNA in saliva by inhibiting a highly expressed nuclease.
Venkata Partha Sarathi Amineni, Georg Petschenka, Aline Koch   +2 more
wiley   +1 more source

SLAMF7 (CD319) enhances cytotoxic T-cell differentiation and sensitizes CD8⁺ T cells to immune checkpoint blockade. [PDF]

Front Immunol
Sander JE, Han I, Fickenscher L, Schmidt JP, Kroll H, Vosikova T, Durisin M, Lingel H, Brunner-Weinzierl MC.   +8 more
europepmc   +1 more source

Cell-Mediated Lympholysis of Fluorescein Isothiocyanate-Conjugated Autologous Human Cells: Evidence for Hapten-Specific Altered-Self Reactive Human Cytotoxic T Lymphocytes

, 1979
Steven Friedman, O H Irigoyen, Janet Kuhns, Leonard Chess   +3 more
openalex   +1 more source

Antigen specific and MHC nonrestricted cytotoxicity of T cell receptor alpha beta+ and gamma delta+ human T cell clones isolated in IL-4. [PDF]

, 1989
Xavier Paliard, Hans Yssel, Dominique Blanchard, J A Waitz, J Devriès, Hergen Spits   +5 more
openalex   +1 more source

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source

Influenza A virus disruption of dendritic cell-natural killer cell crosstalk impacts activation of naïve helper and cytotoxic T cell subsets. [PDF]

Immunohorizons
Morson CA, Uppalapati CK, Lopez BS, Kronstad LM.   +3 more
europepmc   +1 more source

Neoadjuvant chemotherapy remodels the tumor immune microenvironment by increasing activated and cytotoxic T cell, decreasing B cells and macrophages in small cell lung cancer. [PDF]

J Transl Med, 2023
Shang X, Zhang C, Wang K, Wang H.
europepmc   +1 more source

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

Advanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins, Ah Joung Yu, Cheryl T. Gomillion   +2 more
wiley   +1 more source

Primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma with novel FGFR1 fusion treated with pemigatinib. [PDF]

Blood Adv
Torres-Cabala CA, Yescas JA, Zhang Y, Huen A, Sumit G, Tefft K, Tang G, Curry JL, Gunther J, Dabaja B, Iyer S, Miranda RN, Choi J, Nardi V.   +13 more
europepmc   +1 more source