Results 271 to 280 of about 2,965,907 (391)

Vaccination with Tumor Lysate-Pulsed Dendritic Cells Elicits Antigen-Specific, Cytotoxic T-Cells in Patients with Malignant Glioma

Cancer Research, 2004
John S. Yu, Gentao Liu, H. Ying, W. Yong, K. Black, C. Wheeler   +5 more
semanticscholar   +1 more source

Light Activated Induction of Cuproptosis in Resistant Cancer Cells Using Polymeric BODIPY Nanoparticles for Photoactivated Chemotherapy

Advanced Functional Materials, EarlyView.
This article presents a photo‐responsive nanoparticle platform that precisely triggers copper‐dependent cuproptotic cell death in (drug‐resistant) cancer cells. The system remains stable and inactive in the dark but releases cytotoxic species upon red‐light irradiation, achieving potent activity in drug‐resistant breast cancer cells.
Ricarda Zimmermann, Nicolás Montesdeoca, Johannes Karges   +2 more
wiley   +1 more source

Tumor cell spheroid-induced suppression of primary human cytotoxic T cells as a scalable <i>in vitro</i> model of exhaustion. [PDF]

Immunother Adv
Alsubaiti A, Alamir H, Huynh L, Grant T, Aljohani A, Chou PH, Shi Y, Alismail M, Mason LR, Herman A, Bridgeman JS, Holland CJ, Wülfing C.   +12 more
europepmc   +1 more source

Tumor mRNA?loaded dendritic cells elicit tumor-specific CD8+ cytotoxic T cells in patients with malignant glioma

, 2003
Tsutomu Kobayashi, Ryuya Yamanaka, Junpei Homma, Naoto Tsuchiya, Naoki Yajima, Seiichi Yoshida, Ryuichi Tanaka   +6 more
openalex   +2 more sources

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source

CD19-ReTARG^TPR: A Novel Fusion Protein for Physiological Engagement of Anti-CMV Cytotoxic T Cells Against CD19-Expressing Malignancies. [PDF]

Cancers (Basel)
van Wijngaarden AP, Britsch I, Peipp M, Samplonius DF, Helfrich W.   +4 more
europepmc   +1 more source

Photon Avalanching Nanoparticles: The Next Generation of Upconverting Nanomaterials?

Advanced Functional Materials, EarlyView.
This Perspective outlines the mechanistic foundations that enable photon‐avalanche (PA) behavior in lanthanide nanomaterials and contrasts them with emerging application spaces and forward‐looking design strategies. By bridging threshold engineering, energy‐transfer dynamics, and materials engineering, we provide a coherent roadmap for advancing the ...
Kimoon Lee, Yunseo Kim, Hyeong‐ku Jo, Dongjoon Yoon, Byeonghyeok Im, WonJeong Yu, Eui‐Rim On, Changhwan Lee   +7 more
wiley   +1 more source

Required minimal protein domain of flower for synaptobrevin2 endocytosis in cytotoxic T cells. [PDF]

Cell Mol Life Sci
Ravichandran K, Schirra C, Urbansky K, Tu SM, Alawar N, Mannebach S, Krause E, Stevens D, Lancaster CRD, Flockerzi V, Rettig J, Chang HF, Becherer U.   +12 more
europepmc   +1 more source

Poliovirus vaccine vectors elicit antigen-specific cytotoxic T cells and protect mice against lethal challenge with malignant melanoma cells expressing a model antigen

, 1998
Stefanie Mandl, Luis J. Sigal, Kenneth L. Rock, Raul Andino   +3 more
openalex   +1 more source

Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers

Advanced Functional Materials, EarlyView.
A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley   +1 more source