Results 331 to 340 of about 906,600 (363)
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Cytotoxicity and Immunological Response of Gold and Silver Nanoparticles of Different Sizes

Small, 2009
AbstractThe immunological response of macrophages to physically produced pure Au and Ag nanoparticles (NPs) (in three different sizes) is investigated in vitro. The treatment of either type of NP at ≥10 ppm dramatically decreases the population and increases the size of the macrophages.
Ching-Lin Tsai   +2 more
openaire   +3 more sources

DIFFERENTIATION OF IMMUNOLOGICALLY SPECIFIC CYTOTOXIC MACROPHAGES INTO TWO TYPES ON THE BASIS OF RADIOSENSITIVITY

Transplantation, 1974
SUMMARY Macrophages which are cytotoxic in vitro to tumour cells in an immunologically specific manner can be classified into (1) radiosensitive, cytotoxicity totally abolished by 500 R of X-rays; and (2) radioresistant, cytotoxicity unaffected by 500 R but partially ablated by 1,000 R.
Den, Otter W, Evans, R, Alexander, P
openaire   +3 more sources

Human tumor necrosis factor potentiates human interleukin 1-mediated rat pancreatic beta-cell cytotoxicity.

Journal of Immunology, 1987
Previous studies have established that the cytokine interleukin 1 (IL-1) is selectively cytotoxic for isolated human and rat pancreatic beta-cells.
T. Mandrup-Poulsen   +3 more
semanticscholar   +1 more source

Failure of infiltrating precursor cytotoxic T cells to acquire direct cytotoxic function in immunologically privileged sites.

The Journal of Immunology, 1990
Abstract Minor H incompatible P815 tumor cells inoculated into the anterior chamber (AC) of the eyes of BALB/c mice grow progressively, revealing this to be an immunologically privileged site. By contrast, a similar inoculation of tumor cells is rapidly rejected from nonprivileged ocular sites (subconjunctiva).
B R, Ksander, J W, Streilein
openaire   +2 more sources

Viral-bacterial pneumonia in calves: effect of bovine herpesvirus-1 on immunologic functions.

Journal of Infectious Diseases, 1985
The temporal relation between a lung infection with bovine herpesvirus-1, suppression of some immune functions, and susceptibility to secondary bacterial infection resulting in fibrinous pneumonia prompted a study to determine the mechanism(s) involved ...
H. Bielefeldt Ohmann, L. Babiuk
semanticscholar   +1 more source

Overview: Biologicals & Immunologicals: Cytotoxic lymphocytes in the treatment and prevention of AIDS

Expert Opinion on Therapeutic Patents, 1994
At present it seems that the vast majority if not all HIV infections eventually progress to ADS, with inevitable mortality from characteristic infections, neoplasia or more direct central nervous system effects of the virus. This apparently new virus has been strikingly successful in evolutionary terms because of clinical latency and effective ...
TJ Blanchard, Kpwj McAdam
openaire   +2 more sources

Studies on the mechanism of antibody-dependent polymorphonuclear leukocyte-mediated cytotoxicity.

Journal of Immunology, 1977
Human polymorphonuclear leukocytes (PMN) were cytotoxic to mammalian tumor cells (LSTRA) in the presence of anti-LSTRA serum as determined by a 51Cr release assay.
R. Clark, S. Klebanoff
semanticscholar   +1 more source

A longitudinal study of immunological parameters in multiple sclerosis

Journal of the Neurological Sciences, 1979
Complement-dependent gliotoxic antibody activity was determined in 22 patients with multiple sclerosis (MS) and 19 normal control persons. Peripheral blood serum was collected from MS patients at about 4-week intervals for one year, and the results of cytotoxicity tests correlated with the course of disease.
Toni Gradl, Pearl Mar, Christa Dörner
openaire   +3 more sources

An immunological suppressor cell inactivating cytotoxic T-lymphocyte precursor cells recognizing it

Nature, 1980
The immune system does not normally react against self components. Originally, it was postulated that self-reactive cells were somehow deleted or blocked. More recent thinking is that such cells are suppressed by regulatory networks similar to those limiting the immune response against non-self determinants. Both mechanisms may exist. I describe here a
openaire   +3 more sources

Immunologically Mediated Cytotoxicity against Human Eye Muscle Cells in Graves’ Ophthalmopathy*

The Journal of Clinical Endocrinology & Metabolism, 1986
The possible roles of antibody-mediated complement-dependent cytotoxicity (AMC), antibody-dependent killer (K) cell-mediated cytotoxicity (ADCC), and spontaneous, natural killer (NK) cell-mediated cytotoxicity (NKC) against human eye muscle cells in the pathogenesis of Graves' ophthalmopathy were investigated, using as targets human eye muscle cells ...
J. How   +5 more
openaire   +2 more sources

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