Results 61 to 70 of about 34,355 (311)
Table_2_Impaired Antibody-Dependent Cellular Cytotoxicity in a Spanish Cohort of Patients With COVID-19 Admitted to the ICU.docx [PDF]
, 2021 SARS-CoV-2 infection causes COVID-19, ranging from mild to critical disease in symptomatic subjects. It is essential to better understand the immunologic responses occurring in patients with the most severe outcomes.
Miguel Cervero (5154848) +15 more
core +1 more source
Immunity to pathogens taught by specialized human dendritic cell subsets.
Frontiers in Immunology, 2015 Dendritic cells (DC) are specialized antigen-presenting cells (APC) that have a key role in immune responses, because they bridge the innate and adaptive arms of the immune system.
Jens A. E. Geginat +7 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Immunologic principles of allergic disease [PDF]
, 2022 S.1015-1027Allergy either results from a pathological excessive immune reaction, or from the defective induction of tolerance to otherwise harmless antigens. Allergic reactions are mounted by mechanisms of innate and adaptive immunity. The development of
Treudler, Regina +4 more
core +1 more source
Iranian Journal of Allergy, Asthma and Immunology, 2006 It has been recognized that acute and chronic stress has an impact on the immune system. Acute stress may have a stimulating effect on the immune system, while in the case of chronic stress specially depression, the immune system could be down-regulated.
Alireza alib +4 more
doaj
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Evaluation of whole blood as effector for antibody-dependent cellular cytotoxicity against autologous targets [PDF]
, 1980 An assay for antibody-dependent cell-mediated cytotoxicity which uses whole blood as effector and autologous lymphocytes sensitized with rabbit anti-human lymphocyte serum as targets is assessed. Comparison with performances of purified lymphocytes shows
Dupont, Elisabeth
core
BMC Oral HealthBackground/Purpose This retrospective immunohistological pilot study aimed to investigate the influence of natural killer group 2, member D (NKG2D) ligand expression on ameloblastoma recurrence after surgical resection.
Mee-seon Kim +8 more
doaj +1 more source