Gold nanoparticle surface chemistry affects multiple parameters of cytotoxicity in an ovarian cancer model [PDF]
, 2020 Ovarian cancer is one of the deadliest types of cancer, and traditional treatments such as chemotherapy and radiation therapy cause harmful side effects to healthy tissue.
MacDougall, Rachel M.
core +1 more source
Evidence for Immunologic Mechanisms in Human Vitiligo: Patients' Sera Induce Damage to Human Melanocytes In Vitro by Complement-Mediated Damage and Antibody-Dependent Cellular Cytotoxicity [PDF]
, 1988 Human vitiligo is a common depigmenting disorder that is often associated with polyendocrinopathies. The etiology of vitiligo is unknown although there is indirect evidence of a strong association between antimelanocyte antibodies in animal and human ...
David A. Norris +7 more
core +1 more source
Image_1_Impaired Antibody-Dependent Cellular Cytotoxicity in a Spanish Cohort of Patients With COVID-19 Admitted to the ICU.tif [PDF]
, 2021 SARS-CoV-2 infection causes COVID-19, ranging from mild to critical disease in symptomatic subjects. It is essential to better understand the immunologic responses occurring in patients with the most severe outcomes.
Miguel Cervero (5154848) +15 more
core +1 more source
In vitro bio-immunological and cytotoxicity studies of poly(2-oxazolines)
Journal of Materials Science: Materials in Medicine, 2011 Poly(2-oxazolines) with varying alkyl chain lengths (e.g., methyl, ethyl, aryl) and molar masses have been tested for cell cytotoxicity in vitro. A standard 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay was used for the estimation of cell viability.
Juraj, Kronek +5 more
openaire +2 more sources
Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review
Pediatric Blood &Cancer, EarlyView.ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean +7 more
wiley +1 more source
Immunological aspects of persistent hepatitis B in children [PDF]
, 2001 We studied the immunological status of 203 children having persistence Hepatitis B (positive HBsAg) ranging in age from 6 to 14 years in Semarang Municipality.
Notoatmojo, Harsoyo
core
Epstein-Barr virus infection and immunologic dysfunction in patients with aqueous tear deficiency [PDF]
, 1990 The authors tested their hypothesis that Epstein-Barr virus (EBV) infection is a risk factor for aqueous tear deficiency (ATD) by evaluating 38 ATD patients and 17 controls for serologic evidence of EBV infection.
Stephen C. Pflugfelder +17 more
core +1 more source
Natural Killer cells and liver fibrosis
Frontiers in Immunology, 2016 In the 40 years since the discovery of Natural Killer (NK) cells it has been well established that these innate lymphocytes are important for early and effective immune responses against transformed cells and infections with different pathogens.
Frank eFasbender +3 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Association between cetuximab response and differential immunologic gene expression signatures in colorectal cancer metastases. [PDF]
, 2016 558 Background: Different immune cell infiltrates into colorectal cancer (CRC) tumors are associated with different prognoses. Tumor-associated macrophages contribute to immune evasion and accelerated tumor progression.
Autumn Jackson McRee +3 more
core +1 more source