Results 31 to 40 of about 288,657 (306)

SDF-1α Reduces Human Natural Killer Cell Cytotoxicity against Chronic Myelogenous Leukemia K562 Cells

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2019
Stromal cell-derived factor-1 alpha (SDF-1α) has been shown to be up-regulated in a variety of malignancies. So that, its expression is associated with poor prognosis and invasiveness.
Alireza Mardomi   +4 more
doaj   +1 more source

Fibril Fragmentation Enhances Amyloid Cytotoxicity [PDF]

open access: yes, 2009
Fibrils associated with amyloid disease are molecular assemblies of key biological importance, yet how cells respond to the presence of amyloid remains unclear. Cellular responses may not only depend on the chemical composition or molecular properties of
Xue, Wei-Feng   +5 more
core   +1 more source

Tim-3 Is Upregulated in NK Cells during Early Pregnancy and Inhibits NK Cytotoxicity toward Trophoblast in Galectin-9 Dependent Pathway. [PDF]

open access: yesPLoS ONE, 2016
NK cells accumulate at the maternal-fetal interface (MFI) and play essential roles in maintaining immune tolerance during pregnancy. The mechanisms that facilitate NK cells tolerance to fetal tissue are largely unknown.
Jintang Sun   +9 more
doaj   +1 more source

Cytotoxicity of polycarbonate orthodontic brackets

open access: yesBrazilian Journal of Oral Sciences, 2015
Aim: To assess the cytotoxicity of polycarbonate orthodontic brackets. Methods: Polycarbonate brackets from two different manufacturers, namely, Composite bracket (Morelli™) and Silkon Plus bracket (American Orthodontics™), were assessed.
Matheus Melo Pithon   +6 more
doaj   +1 more source

Cytotoxicity of Reparative Endodontic Cements on Human Periodontal Ligament Stem Cells

open access: yesPesquisa Brasileira em Odontopediatria e Clínica Integrada, 2022
Objective: To compare the cytotoxicity of commercial reparative endodontic cements on human periodontal ligament stem cells (hPDLSCs). Material and Methods: The culture of hPDLSCs was established.
Marlus da Silva Pedrosa   +4 more
doaj  

In vitro Cytotoxicity in Delayed-Type Hypersensitivity and Immunologic Tolerance.

open access: yesExperimental Biology and Medicine, 1964
SummaryPicryl chloride was found to exert a lethal effect in vitro on leukocytes, principally lymphocytes, from guinea pigs exhibiting delayed-type skin reactivity to this hapten in the absence of antibody and complement. This reaction was found to be immunologically specific.
D M, LUBAROFF, R E, RITTS
openaire   +2 more sources

The Biological Influence and Clinical Relevance of Polymorphism Within the NKG2D Ligands

open access: yesFrontiers in Immunology, 2018
NKG2D is a major regulator of the activity of cytotoxic cells and interacts with eight different ligands (NKG2DL) from two families of MIC and ULBP proteins.
Jianmin Zuo, Fiyaz Mohammed, Paul Moss
doaj   +1 more source

Genetic Modification of Limbal Stem Cells to Decrease Allogeneic Immune Responses

open access: yesFrontiers in Immunology, 2021
Limbal stem cell (LSC) transplantation is the only efficient treatment for patients affected by LSC deficiency (LSCD). Allogeneic LSC transplantation is one of the most successful alternative for patients with bilateral LSCD.
Emilio Valdivia   +9 more
doaj   +1 more source

Mac-1 (CD11b/CD18) is essential for Fc receptor-mediated neutrophil cytotoxicity and immunologic synapse formation.

open access: yes, 2001
Contains fulltext : 121093.pdf (Publisher’s version ) (Open Access)Receptors for human immunoglobulin (Ig)G and IgA initiate potent cytolysis of antibody (Ab)-coated targets by polymorphonuclear leukocytes (PMNs).
Jan G. J. van de Winkel   +13 more
core   +1 more source

Phosphorylation of the myosin IIA tailpiece regulates single myosin IIA molecule association with lytic granules to promote NK-cell cytotoxicity

open access: yes, 2011
Natural killer (NK) cells are innate immune lymphocytes that provide critical defense against virally infected and transformed cells. NK-cell cytotoxicity requires the formation of an F-actin rich immunologic synapse (IS), as well as the polarization of ...
Emily M. Mace   +8 more
core   +2 more sources

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