Results 31 to 40 of about 34,355 (311)

Genetic Modification of Limbal Stem Cells to Decrease Allogeneic Immune Responses

Frontiers in Immunology, 2021
Limbal stem cell (LSC) transplantation is the only efficient treatment for patients affected by LSC deficiency (LSCD). Allogeneic LSC transplantation is one of the most successful alternative for patients with bilateral LSCD.
Emilio Valdivia, Marina Bertolin, Claudia Breda, Marco Carvalho Oliveira, Anna Katharina Salz, Nicola Hofmann, Martin Börgel, Rainer Blasczyk, Stefano Ferrari, Constanca Figueiredo   +9 more
doaj   +1 more source

Lycium barbarum Polysaccharide Promotes Maturation of Dendritic Cell via Notch Signaling and Strengthens Dendritic Cell Mediated T Lymphocyte Cytotoxicity on Colon Cancer Cell CT26-WT [PDF]

, 2018
Lycium barbarum polysaccharide (LBP) is the major function component of Lycium barbarum L. and has been previously reported to induce the phenotypic and functional maturation of dendritic cells (DCs) as well as activating T lymphocytes.
Hongzhi Sun, Guang Bai, Feng Ding, Mingxing Liu, Tao Yang, Yang Wang, Wei Wang, Dongsheng Li, Qing Li   +8 more
core   +1 more source

In Vitro Analysis of the Proliferation of HaCaT Cells Stimulated by Pigments Used for Maxillofacial Prostheses

Journal of Orofacial Sciences, 2019
Introduction: Although physical and mechanical properties are extremely important for the effectiveness of prosthetic treatment, materials used for facial rehabilitation should be biocompatible, as the maxillofacial prosthesis is in close contact with ...
Marcelo Coelho Goiato, Adhara Smith Nobrega, Estefania Marrega Malavazi, Aline Satie Takamiya, Sandra Helena Penha de Oliveira   +4 more
doaj   +1 more source

Negative Regulation and Protective Function of Natural Killer Cells in HIV Infection: Two Sides of a Coin

Frontiers in Immunology, 2022
Natural killer (NK) cells play an important immunologic role, targeting tumors and virus-infected cells; however, NK cells do not impede the progression of human immunodeficiency virus (HIV) infection.
Yu Sun, Jie Zhou, Yongjun Jiang
doaj   +1 more source

Cytotoxic Isoantibodies and Immunologic Enhancement in Mice.

Experimental Biology and Medicine, 1966
Summary1. Cytotoxic isoantibodies and hemagglutinins are stimulated in response to H-2 isoantigenic differences between graft and host in mice. 2. This study offers data correlating cytotoxic isoantibody and immunological enhancement. 3. The mechanism of immunological enhancement has been shown to be associated with peripheral as well as central ...
openaire   +2 more sources

Effect of immunization with fetal cells on adenovirus-12 oncogenesis [PDF]

, 1974
The effect of immunization with hamster fetal cells on the tumor induction by adnovirus type 12 was studied by in vivo and in vitro. The immunization with lO-day old fetal cells showed a recognizable inhibition on the tumor induction by adenovirus type ...
Abe, Shinji
core   +1 more source

NKp46 clusters at the immune synapse and regulates NK cell polarization

Frontiers in Immunology, 2015
Natural killer cells play an important role in first-line defense against tumor and virus-infected cells. The activity of NK cells is tightly regulated by a repertoire of cell-surface expressed inhibitory and activating receptors.
Uzi eHadad, Uzi eHadad, Timothy J Thauland, Olivia M Martinez, Manish J Butte, Angel ePorgador, Sheri M Krams   +6 more
doaj   +1 more source

Immune modulation of i.v. immunoglobulin in women with reproductive failure

Reproductive Medicine and Biology, 2018
Background The mechanism of maternal immune tolerance of the semi‐allogenic fetus has been explored extensively. The immune reaction to defend from invasion by pathogenic microorganisms should be maintained during pregnancy.
Ae R. Han, Sung K. Lee
doaj   +1 more source

Cx43-Gap Junctions Accumulate at the Cytotoxic Immunological Synapse Enabling Cytotoxic T Lymphocyte Melanoma Cell Killing [PDF]

International Journal of Molecular Sciences, 2019
Upon tumor antigen recognition, cytotoxic T lymphocytes (CTLs) and target cells form specialized supramolecular structures, called cytotoxic immunological synapses, which are required for polarized delivery of cytotoxic granules. In previous reports, we described the accumulation of connexin 43 (Cx43)-formed gap junctions (GJs) at natural killer (NK ...
Francisca Hofmann, Mariela Navarrete, Javiera Álvarez, Israel Guerrero, María Alejandra Gleisner, Andrés Tittarelli, Flavio Salazar-Onfray   +6 more
openaire   +2 more sources

Association Between Dinutuximab Beta Exposure and Post‐End‐of‐Treatment Survival in Neuroblastoma: A Weighted Patient‐Level Analysis of Three Clinical Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives The association between exposure to dinutuximab beta (DB) and event‐free survival (EFS) or overall survival (OS) of neuroblastoma patients was assessed using data collected during three clinical trials (five cohorts). Methods A systematic review (March 2026) was conducted to identify relevant studies (prospective; registered DB ...
Przemysław Holko, Holger N. Lode, Alberto Garaventa, Carla Manzitti, Roberto Luksch, Dominique Valteau‐Couanet, Marion Gambart, John Anderson, Juliet Gray, Adela Canete, Lucas Moreno, Aleksandra Wieczorek, Cormac Owens, Shifra Ash, Isaac Yaniv, Genevieve Laureys, Hans Loibner, Katarzyna Śladowska, Ruth Ladenstein, Paweł Kawalec   +19 more
wiley   +1 more source